![Philip Pallmann](https://profiles-cardiff.imgix.net/attachments/3624?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Philip Pallmann
- Ar gael fel goruchwyliwr ôl-raddedig
Timau a rolau for Philip Pallmann
Prif Gymrawd Ymchwil - Ystadegau
Ymchwil Canolfan Treialon
Trosolwyg
Rwy'n Brif Gymrawd Ymchwil yn y Ganolfan Treialon Ymchwil lle rwy'n gweithio fel ystadegydd meddygol ar ddylunio, ymddygiad, dadansoddi ac adrodd ar hapdreialon rheoledig ac astudiaethau eraill a gynlluniwyd yn dda.
Mae fy nghefndir mewn ystadegau cymhwysol, ond rwy'n gweithio ar draws ystod eang o feysydd clinigol gan gynnwys heintiau, clefydau niwroddirywiol ac iechyd y boblogaeth, yn ogystal ag ar hyrwyddo methodoleg treialon clinigol, yn enwedig dulliau dylunio effeithlon fel dyluniadau addasol.
Rwy'n cyd-arwain Gweithgor Dyluniadau Addasol Partneriaeth Ymchwil Methodoleg Treialon MRC-NIHR, ynghyd â Sofía Villar.
Rwy'n aelod o bwyllgor cyllido MRC-NIHR Effeithiolrwydd a Gwerthuso Mecanwaith (EME).
Rwy'n Olygydd Cyswllt ar gyfer y cyfnodolyn a adolygir gan gymheiriaid Trials.
Cyhoeddiad
2025
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9(2), pp. 121-130. (10.1016/S2352-4642(24)00306-7)
- Bell, S. F., Taylor, H., Pallmann, P., Collins, P. and the OBS Cymru collaborators (online Supporting Information Appen, . 2025. Relationship between the dual platelet‐inhibited ROTEM ® Sigma FIBTEM assay and Clauss fibrinogen during postpartum haemorrhage. Anaesthesia: Peri-operative medicine, critical care and pain 80(1), pp. 104-106. (10.1111/anae.16455)
- Busse-Morris, M. et al. 2025. Effectiveness of a personalised self-management intervention for people living with long covid (Listen trial): pragmatic, multicentre, parallel group, randomised controlled trial. BMJ Medicine 4(1), article number: e001068. (10.1136/bmjmed-2024-001068)
- Naseem, R., Howe, N., Pretorius, S., Williams, C., Lendrem, C., Pallmann, P. and Carrol, E. D. 2025. Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection. NIHR Open Research 4, article number: 35. (10.3310/nihropenres.13568.2)
2024
- Williams-Thomas, R. et al. 2024. Sexual health and healthy relationships for Further Education (SaFE) in Wales and England: results from a pilot cluster randomised controlled trial. BMJ Open 14, article number: e091355. (10.1136/bmjopen-2024-091355)
- Barry, T. D., Hester, Y., Pallmann, P., Thomas-Jones, E., Underwood, J., Backx, M. and Barry, S. M. 2024. The role of nurses in national TB control programs: qualitative insights from TB cohort review in Wales. Medical Research Archives 12(12) (10.18103/mra.v12i12.6063)
- Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79(11), pp. 2792-2800., article number: dkae246. (10.1093/jac/dkae246)
- Schroeder, E. et al. 2024. The cost-effectiveness and cost-consequences of a school-based social worker intervention: a within-trial economic evaluation. Children and Youth Services Review 166, article number: 107928. (10.1016/j.childyouth.2024.107928)
- Robertson, D. S., Burnett, T., Choodari-Oskooei, B., Dimairo, M., Grayling, M., Pallmann, P. and Jaki, T. 2024. Confidence intervals for adaptive trial designs I: a methodological review. [Online]. arXiv: Cornell University. (10.48550/arXiv.2411.08495) Available at: https://doi.org/10.48550/arXiv.2411.08495
- Robertson, D. S., Burnett, T., Choodari-Oskooei, B., Dimairo, M., Grayling, M., Pallmann, P. and Jaki, T. 2024. Confidence intervals for adaptive trial designs II: case study and practical guidance. [Online]. arXiv: Cornell University. (10.48550/arXiv.2411.08771) Available at: https://doi.org/10.48550/arXiv.2411.08771
- Jarvis, R. C., Pallmann, P., Clements, C. and Joshi, H. 2024. Development and preliminary validation of a diagnostic prediction model to optimise outpatient management of patients with urolithiasis using Urinary Stones and Intervention Quality of Life (USIQoL) measure. Quality of Life Research 33, pp. 2809–2818. (10.1007/s11136-024-03733-w)
- Bennett, V. et al. 2024. Student perspectives on school-based social workers: A mixed-methods study. Journal of Children's Services 19(3), pp. 189-221. (10.1108/JCS-04-2023-0021)
- Smith, E. E., Gwilym, B. L., Pallmann, P. and Bosanquet, D. C. 2024. Comment on: "Integrating human intuition into prediction algorithms for improved surgical risk stratification". Annals of Surgery Open 5(3), article number: e485. (10.1097/AS9.0000000000000485)
- Elsmore, A. et al. 2024. The OBS UK Dashboard: an interactive tool for representative trial site selection to facilitate equality and diversity in maternity research. Trials 25, article number: 629. (10.1186/s13063-024-08487-x)
- Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25, article number: 557. (10.1186/s13063-024-08380-7)
- Wood, S. et al. 2024. Family group conference provision in UK local authorities and associations with children looked after rates. The British Journal of Social Work 54(5), pp. 2045-2066. (10.1093/bjsw/bcae019)
- Ioakeimidis, V. et al. 2024. Protocol for a randomised controlled unblinded feasibility trial of HD-DRUM, a rhythmic movement training application for cognitive and motor symptoms in people with Huntington’s disease. BMJ Open 14(7), article number: e082161. (10.1136/bmjopen-2023-082161)
- Naseem, R., Howe, N., Pretorius, S., Williams, C., Lendrem, C., Pallmann, P. and Carrol, E. D. 2024. Mapping decision-making pathways: determination of intervention entry points for diagnostic tests in suspected serious infection. NIHR Open Research 4, article number: 35. (10.3310/nihropenres.13568.1)
- Scourfield, J. et al. 2024. Family group conferencing for children and families: Evaluation of implementation, context and effectiveness (Family VOICE). Study protocol. PLoS ONE 19(6), article number: e0300834. (10.1371/journal.pone.0300834)
- Webb, E. J. D. et al. 2024. Evidence of quality of life for hospitalised patients with COVID-19: a scoping review. Health Technology Assessment (10.3310/ATPR4281)
- Schroeder, E. et al. 2024. The cost-effectiveness and cost-consequences of a school-based social worker intervention: a within-trial economic evaluation. [Online]. SSRN. (10.2139/ssrn.4776734)
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8(1), article number: zrad135. (10.1093/bjsopen/zrad135)
- Kumwenda, M. et al. 2024. Identifying critically ill children in Malawi: A modified qSOFA score for low-resource settings. PLOS Global Public Health 4(1), article number: e0002388. (10.1371/journal.pgph.0002388)
2023
- Dimairo, M., Bradburn, M., Flight, L., Jaki, T., Pallmann, P., Wheeler, G. M. and Cooper, C. 2023. A practical adaptive designs toolkit: making adaptive designs more accessible. Presented at: Society for Clinical Trials 44th Annual Meeting, Baltimore, 21-24 May 2023, Vol. 20. Vol. CP7-2. SAGE Publications pp. 37-37., (10.1177/17407745231210703)
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13(12), article number: e077117. (10.1136/bmjopen-2023-077117)
- Ioakeimidis, V. et al. 2023. Protocol for a randomised controlled feasibility trial of HD-DRUM, a rhythmic movement training application for cognitive and motor symptoms in people with Huntington's disease. [Online]. medRxiv: medRxiv. (10.1101/2023.11.15.23298581) Available at: https://doi.org/10.1101/2023.11.15.23298581
- Metzler-Baddeley, C., Busse-Morris, M., Drew, C., Pallmann, P., Cantera Gomez, J., Ioakeimidis, V. and Rosser, A. 2023. HD-DRUM, a tablet-based drumming training App intervention for people with Huntington Disease: App development study. Journal of Medical Internet Research 2023(7), article number: e48395. (10.2196/48395)
- Law, M. et al. 2023. Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing. Trials 24, article number: 640. (10.1186/s13063-023-07576-7)
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse, M., Godley, M. D. and Griffin, B. A. 2023. A tutorial comparing different covariate balancing methods with an application evaluating the causal effects of substance use treatment programs for adolescents. Health Services and Outcomes Research Methodology 23, pp. 115-148. (10.1007/s10742-022-00280-0)
- Robertson, D. S., Choodari-Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2023. Point estimation for adaptive trial designs II: practical considerations and guidance. Statistics in Medicine 42(14), pp. 2496-2520. (10.1002/sim.9734)
- Karanja, J., Pallmann, P. and Poehling, H. 2023. Systemic slow-release neem formulations: the future of cabbage aphids, Brevicoryne brassicae control. Open Access Library Journal 10, article number: e10158. (10.4236/oalib.1110158)
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
- Metzler-Baddeley, C., Busse, M., Drew, C., Pallmann, P., Cantera Gomez, J., Ioakeimidis, V. and Rosser, A. E. 2023. Applying an integrated knowledge translation framework approach to develop a tablet-based rhythmic movement training intervention for people with Huntington’s disease. [Online]. JMIR Preprints. (10.2196/preprints.48395) Available at: https://preprints.jmir.org/preprint/48395
- Adara, L. et al. 2023. The Social Workers in Schools Trial: An evaluation of school based social work.. Project Report. Early Intervention Foundation.
- Potter, C. et al. 2023. Effectiveness and cost-effectiveness of a personalised self-management intervention for living with long covid: protocol for the listen randomised controlled trial. Trials 24, article number: 75. (10.1186/s13063-023-07090-w)
2022
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Wood, S. et al. 2022. A UK-wide survey of family group conference provision. Project Report. Cardiff: CASCADE.
- Llewelyn, M. J., West, R. M., Carrol, E. D., Pallmann, P. and Sandoe, J. A. T. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data - authors' response. Journal of Antimicrobial Chemotherapy 77(11), pp. 3211-3212., article number: dkac315. (10.1093/jac/dkac315)
- Kumwenda, M. et al. 2022. Identifying critically ill children at risk of dying during hospital admission in Malawi: prognostic accuracy of a modified qSOFA score for low-resource settings. Presented at: 11th World Congress on Pediatric Intensive and Critical Care, Virtual, 12-16 July 2022, Vol. 23. Vol. OP044., (10.1097/01.pcc.0000899856.14238.94)
- Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2022. Point estimation for adaptive trial designs I: A methodological review. Statistics in Medicine (10.1002/sim.9605)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Metzler-Baddeley, C., Busse, M. E., Drew, C. J., Pallmann, P., Jones, D. K. and Rosser, A. 2022. HD-DRUM – a novel computerised drumming training for movement and cognitive abilities in people with Huntington’s disease – app development and protocol of a randomised controlled feasibility study. Presented at: EHDN 2022 Plenary Meeting, Bologna, Italy, 16-18 September 2022, Vol. 93. Vol. S1. pp. A100-A101., (10.1136/jnnp-2022-ehdn.267)
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2022. Covariate balancing & weighting web app (COBWEB): an online tool simplifying robust causal inference in observational studies. Journal of Neurology, Neurosurgery and Psychiatry 93(S1), article number: A44. (10.1136/jnnp-2022-ehdn.114)
- Markoulidakis, A., Busse, M., Doheny, E., Drew, C., Kirby, N. and Pallmann, P. 2022. Lifestyle index for individuals with HD (LifeHD): an aggregated measure that characterises the lifestyle habits of individuals with HD. Presented at: EHDN 2022 Plenary Meeting, Bologna, Italy, 16-18 September, Vol. 93. Vol. S1., (10.1136/jnnp-2022-ehdn.111)
- Love, S. B. et al. 2022. Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units. Trials 23, article number: 757. (10.1186/s13063-022-06680-4)
- Westlake, D. et al. 2022. Evaluating a school-based intervention through routine local authority data and national school data: challenges and opportunities. Presented at: International Population Data Linkage Conference 2022, 7 - 9 September 2022, Vol. 7. Vol. 3., (10.23889/ijpds.v7i3.1886)
- Wason, J. M. S. et al. 2022. Practical guidance for planning resources required to support publicly‑funded adaptive clinical trials. BMC Medicine 20, article number: 254. (10.1186/s12916-022-02445-7)
- Morgan-Jones, P. et al. 2022. Monitoring and managing lifestyle behaviours using wearable activity trackers: a mixed methods study of views from the Huntington's disease community. JMIR Formative Research 6(6), article number: e36870. (10.2196/36870)
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Westlake, D. et al. 2022. The SWIS trial: protocol of a pragmatic cluster randomised controlled trial of school based social work. PLoS ONE 17(6), article number: e0265354. (10.1371/journal.pone.0265354)
- Llewelyn, M. J. et al. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77(4), pp. 1189-1196. (10.1093/jac/dkac017)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
- Powell, E., James, D., Collis, R., Collins, P., Pallmann, P. and Bell, S. 2022. Introduction of standardized, cumulative quantitative measurement of blood loss into routine maternity care. Journal of Maternal-Fetal and Neonatal Medicine 35(8), pp. 1491-1497. (10.1080/14767058.2020.1759534)
- Dimairo, M. et al. 2022. PANDA: a practical adaptive and novel designs and analysis toolkit. [Online]. University of Sheffield. Available at: https://panda.shef.ac.uk/
2021
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. CoBWeb: a user-friendly web application to estimate causal treatment effects from observational data using multiple algorithms. [Online]. Cornell University. Available at: https://arxiv.org/abs/2112.05035
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
- Wilson, N. et al. 2021. Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project. BMC Medicine 19, article number: 251. (10.1186/s12916-021-02124-z)
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. Examining the effect of exercise on the progression and severity of Huntington's disease using different covariate balancing methods and simulated data derived from the PACE-HD study. Presented at: Huntington Study Group 2020: HD in Focus, 29-31 October 2020, Vol. 92. Vol. 1. BMJ Publishing Group, (10.1136/jnnp-2021-EHDN.74)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Romaine, S. T. et al. 2021. Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open 11(5), article number: e044091. (10.1136/bmjopen-2020-044091)
- Robertson, D. S., Choodari-Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2021. Point estimation for adaptive trial designs. [Online]. Cornell University. Available at: https://arxiv.org/abs/2105.08836
- Bell, S. F. et al. 2021. Reduction in massive postpartum haemorrhage and red blood cell transfusion during a national quality improvement project, Obstetric Bleeding Strategy for Wales, OBS Cymru: an observational study. BMC Pregnancy and Childbirth 21, article number: 377. (10.1186/s12884-021-03853-y)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
- Bell, S. F. et al. 2021. Reduction in massive postpartum haemorrhage and red blood cell transfusion during a national quality improvement project, Obstetric Bleeding Strategy for Wales, OBS Cymru: an observational study (October 11, 2020). Working paper. SSRN: SSRN. Available at: http://doi.org/10.2139/ssrn.3746928
- Wheeler, M., Powell, E. and Pallmann, P. 2021. Use of high-fidelity simulation training for radiology healthcare professionals in the management of acute medical emergencies. British Journal of Radiology 94(1117), article number: 20200520. (10.1259/bjr.20200520)
- Drew, C. et al. 2021. Protocol for an open label, phase I trial within a cohort of fetal cell transplants in people with Huntington’s disease. Brain Communications 3(1), article number: fcaa230. (10.1093/braincomms/fcaa230)
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. How balance and sample size impact bias in the estimation of causal treatment effects: a simulation study. [Online]. Cornell University. Available at: https://arxiv.org/abs/2107.09009
2020
- Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. and Jaki, T. 2020. Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs. BMC Medicine 18, article number: 352. (10.1186/s12916-020-01808-2)
- Romaine, S. T. et al. 2020. Accuracy of a modified qSOFA score for predicting critical care admission in febrile children. Pediatrics 146(4), article number: e20200782. (10.1542/peds.2020-0782)
- Dimairo, M. et al. 2020. The Adaptive designs CONSORT Extension (ACE) Statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ 369, article number: m115. (10.1136/bmj.m115)
- Dimairo, M. et al. 2020. The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 21, article number: 528. (10.1186/s13063-020-04334-x)
- Parkes, M., Lunt, M., Pallmann, P. and Felson, D. 2020. Futility of the treatment, rather than futility of the trial, as the primary focus of interim analyses in clinical trials. Presented at: Society for Clinical Trials (SCT) 40th Annual Meeting, New Orleans, LA, US, 19-22 May 2019, Vol. 17. Vol. 1_Supp. SAGE Publications (UK and US) pp. 62., (10.1177/1740774520907457)
- Pallmann, P. et al. 2020. Designing and evaluating dose-escalation studies made easy: the MoDEsT web app. Clinical Trials 17(2), pp. 147-156. (10.1177/1740774519890146)
- Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. and Jaki, T. 2020. Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs. [Online]. arXiv. Available at: https://arxiv.org/abs/2006.12811
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse-Morris, M. and Griffin, B. A. 2020. A tutorial comparing different covariate balancing methods with an application evaluating the causal effect of exercise on the progression of Huntington’s disease. [Online]. arXiv. Available at: https://arxiv.org/abs/2010.09563
2019
- Dimairo, M. et al. 2019. Introducing the Adaptive designs CONSORT Extension (ACE) Statement to improve reporting of randomised trials that use an adaptive design (P-7). Presented at: 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK, 6-9 October 2019. BioMed Central pp. -., (10.1186/s13063-019-3688-6)
- Hornbacher, J., Rumlow, A., Pallmann, P., Turcios, A. E., Riemenschneider, A. and Papenbrock, J. 2019. The levels of sulfur-containing metabolites in Brassica napus are not influenced by the circadian clock but diurnally. Journal of Plant Biology 62(5), pp. 359-373. (10.1007/s12374-019-0143-x)
- Drew, C. J. G. et al. 2019. A protocol for a randomised controlled, double-blind feasibility trial investigating fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetine, Learning and Memory in Epilepsy (FLAME trial). Pilot and Feasibility Studies 5(1), article number: 87. (10.1186/s40814-019-0474-x)
- Jansen, J. O., Pallmann, P., MacLennan, G. and Campbell, M. K. 2019. Bayesian clinical trial designs another option for trauma trials? Erratum. Journal of Trauma and Acute Care Surgery 86(4), pp. 760. (10.1097/TA.0000000000002236)
- Jaki, T., Pallmann, P. and Magirr, D. 2019. The R package MAMS for designing multi-arm multi-stage clinical trials. Journal of Statistical Software 88(4)
2018
- Dimairo, M. et al. 2018. Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design. BMC Medicine 16(1), article number: 210. (10.1186/s12916-018-1196-2)
- Pallmann, P., Ritz, C. and Hothorn, L. A. 2018. Simultaneous small-sample comparisons in longitudinal or multi-endpoint trials using multiple marginal models. Statistics in Medicine 37(9), pp. 1562-1576. (10.1002/sim.7610)
- Pallmann, P. et al. 2018. Adaptive designs in clinical trials: why use them, and how to run and report them. BMC Medicine 16, article number: 29. (10.1186/s12916-018-1017-7)
2017
- Pallmann, P. and Jaki, T. 2017. Simultaneous confidence regions for multivariate bioequivalence. Statistics in Medicine 36(29), pp. 4585-4603. (10.1002/sim.7446)
- Pallmann, P., Pretorius, M. and Ritz, C. 2017. Simultaneous comparisons of treatments at multiple time points: Combined marginal models versus joint modeling. Statistical Methods in Medical Research 26(6), pp. 2633-2648. (10.1177/0962280215603743)
- Jansen, J. O., Pallmann, P., MacLennan, G. and Campbell, M. K. 2017. Bayesian clinical trial designs: Another option for trauma trials?. Journal of Trauma and Acute Care Surgery 83(4), pp. 736-741. (10.1097/TA.0000000000001638)
- Parkes, M., Lunt, M., Pallmann, P. and Felson, D. T. 2017. The two-stage treatment selection (TSTS) design: a novel approach to treatment selection in clinical trials. Trials 18(S1), pp. 166., article number: P440. (10.1186/s13063-017-1902-y)
- Otieno, J. A., Pallmann, P. and Poehling, H. 2017. Additive and synergistic interactions amongst Orius laevigatus (Heteroptera: Anthocoridae), entomopathogens and azadirachtin for controlling western flower thrips (Thysanoptera: Thripidae). BioControl 62(1), pp. 85-95. (10.1007/s10526-016-9767-7)
- Pallmann, P. 2017. Sample size determination in clinical trials with multiple endpoints. T. Sozu, R. Sugimoto, T. Hamasaki, and S. R. Evans (2015). New York, NY: Springer. 95 pages, ISBN: 978-3-319-22004-8. Biometrical Journal 59(1), pp. 218. (10.1002/bimj.201600135)
2016
- Rumlow, A., Keunen, E., Klein, J., Pallmann, P., Riemenschneider, A., Cuypers, A. and Papenbrock, J. 2016. Quantitative expression analysis in brassica napus by northern blot analysis and reverse transcription-quantitative PCR in a complex experimental setting. PLoS ONE 11(9), article number: e0163679. (10.1371/journal.pone.0163679)
- Pallmann, P. and Hothorn, L. A. 2016. Boxplots for grouped and clustered data in toxicology. Archives of Toxicology 90(7), pp. 1631-1638. (10.1007/s00204-015-1608-4)
- Otieno, J. A., Pallmann, P. and Poehling, H. -. 2016. The combined effect of soil-applied azadirachtin with entomopathogens for integrated management of western flower thrips. Journal of Applied Entomology 140(3), pp. 174-186. (10.1111/jen.12242)
- Pallmann, P. and Hothorn, L. A. 2016. Analysis of means: a generalized approach using R. Journal of Applied Statistics 43(8), pp. 1541-1560. (10.1080/02664763.2015.1117584)
- Pallmann, P. and Schaarschmidt, F. 2016. Common pitfalls when testing additivity of treatment mixtures with chi-square analyses. Journal of Applied Entomology 140(1-2), pp. 135-141. (10.1111/jen.12258)
2015
- Pallmann, P. 2015. Simultaneous Statistical Inference: With Applications in the Life Sciences. T.Dickhaus (2014). Heidelberg: Springer. 180 pages, ISBN: 978-3-642-45181-2.. Biometrical Journal 57(6), pp. 1151-1152. (10.1002/bimj.201500129)
- Pallmann, P. 2015. Analyzing baseball data with R [book review]. Journal of the Royal Statistical Society Series A (Statistics in Society) 178(4), pp. 1099-1099. (10.1111/rssa.3_12138)
- Karanja, J., Poehling, H. and Pallmann, P. 2015. Efficacy and dose response of soil-applied neem formulations in substrates with different amounts of organic matter, in the control of whiteflies, aleyrodes proletella and trialeurodes vaporariorum (hemiptera: aleyrodidae). Journal of Economic Entomology 108(3), pp. 1182-1190. (10.1093/jee/tov047)
- Weese, A., Pallmann, P., Papenbrock, J. and Riemenschneider, A. 2015. Brassica napus L. cultivars show a broad variability in their morphology, physiology and metabolite levels in response to sulfur limitations and to pathogen attack. Frontiers in Plant Science 6, article number: 9. (10.3389/fpls.2015.00009)
2014
- Pallmann, P., Hothorn, L. A. and Djira, G. D. 2014. A Levene-type test of homogeneity of several variances against ordered alternatives. Computational Statistics 29, pp. 1593-1608. (10.1007/s00180-014-0508-z)
- Pallmann, P. 2014. Applied meta-analysis with R. Journal of Applied Statistics 42(4), pp. 914-915. (10.1080/02664763.2014.989464)
2013
- Jaki, T., Pallmann, P. and Wolfsegger, M. J. 2013. Estimation in AB/BA crossover trials with application to bioequivalence studies with incomplete and complete data designs. Statistics in Medicine 32(30), pp. 5469-5483. (10.1002/sim.5886)
- Jaki, T., Pallmann, P. and Wolfsegger, M. J. 2013. Authors' reply to Comments on 'Estimation in AB/BA crossover trials with application to bioequivalence studies with incomplete and complete data designs'. Statistics in Medicine 32(30), pp. 5487-5488. (10.1002/sim.6000)
2012
- Pallmann, P., Schaarschmidt, F., Hothorn, L. A., Fischer, C., Nacke, H., Priesnitz, K. U. and Schork, N. J. 2012. Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices. Molecular Ecology Resources 12(6), pp. 1068-1078. (10.1111/1755-0998.12004)
Cynadleddau
- Dimairo, M., Bradburn, M., Flight, L., Jaki, T., Pallmann, P., Wheeler, G. M. and Cooper, C. 2023. A practical adaptive designs toolkit: making adaptive designs more accessible. Presented at: Society for Clinical Trials 44th Annual Meeting, Baltimore, 21-24 May 2023, Vol. 20. Vol. CP7-2. SAGE Publications pp. 37-37., (10.1177/17407745231210703)
- Kumwenda, M. et al. 2022. Identifying critically ill children at risk of dying during hospital admission in Malawi: prognostic accuracy of a modified qSOFA score for low-resource settings. Presented at: 11th World Congress on Pediatric Intensive and Critical Care, Virtual, 12-16 July 2022, Vol. 23. Vol. OP044., (10.1097/01.pcc.0000899856.14238.94)
- Metzler-Baddeley, C., Busse, M. E., Drew, C. J., Pallmann, P., Jones, D. K. and Rosser, A. 2022. HD-DRUM – a novel computerised drumming training for movement and cognitive abilities in people with Huntington’s disease – app development and protocol of a randomised controlled feasibility study. Presented at: EHDN 2022 Plenary Meeting, Bologna, Italy, 16-18 September 2022, Vol. 93. Vol. S1. pp. A100-A101., (10.1136/jnnp-2022-ehdn.267)
- Markoulidakis, A., Busse, M., Doheny, E., Drew, C., Kirby, N. and Pallmann, P. 2022. Lifestyle index for individuals with HD (LifeHD): an aggregated measure that characterises the lifestyle habits of individuals with HD. Presented at: EHDN 2022 Plenary Meeting, Bologna, Italy, 16-18 September, Vol. 93. Vol. S1., (10.1136/jnnp-2022-ehdn.111)
- Westlake, D. et al. 2022. Evaluating a school-based intervention through routine local authority data and national school data: challenges and opportunities. Presented at: International Population Data Linkage Conference 2022, 7 - 9 September 2022, Vol. 7. Vol. 3., (10.23889/ijpds.v7i3.1886)
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. Examining the effect of exercise on the progression and severity of Huntington's disease using different covariate balancing methods and simulated data derived from the PACE-HD study. Presented at: Huntington Study Group 2020: HD in Focus, 29-31 October 2020, Vol. 92. Vol. 1. BMJ Publishing Group, (10.1136/jnnp-2021-EHDN.74)
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
- Parkes, M., Lunt, M., Pallmann, P. and Felson, D. 2020. Futility of the treatment, rather than futility of the trial, as the primary focus of interim analyses in clinical trials. Presented at: Society for Clinical Trials (SCT) 40th Annual Meeting, New Orleans, LA, US, 19-22 May 2019, Vol. 17. Vol. 1_Supp. SAGE Publications (UK and US) pp. 62., (10.1177/1740774520907457)
- Dimairo, M. et al. 2019. Introducing the Adaptive designs CONSORT Extension (ACE) Statement to improve reporting of randomised trials that use an adaptive design (P-7). Presented at: 5th International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK, 6-9 October 2019. BioMed Central pp. -., (10.1186/s13063-019-3688-6)
Erthyglau
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9(2), pp. 121-130. (10.1016/S2352-4642(24)00306-7)
- Bell, S. F., Taylor, H., Pallmann, P., Collins, P. and the OBS Cymru collaborators (online Supporting Information Appen, . 2025. Relationship between the dual platelet‐inhibited ROTEM ® Sigma FIBTEM assay and Clauss fibrinogen during postpartum haemorrhage. Anaesthesia: Peri-operative medicine, critical care and pain 80(1), pp. 104-106. (10.1111/anae.16455)
- Busse-Morris, M. et al. 2025. Effectiveness of a personalised self-management intervention for people living with long covid (Listen trial): pragmatic, multicentre, parallel group, randomised controlled trial. BMJ Medicine 4(1), article number: e001068. (10.1136/bmjmed-2024-001068)
- Naseem, R., Howe, N., Pretorius, S., Williams, C., Lendrem, C., Pallmann, P. and Carrol, E. D. 2025. Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection. NIHR Open Research 4, article number: 35. (10.3310/nihropenres.13568.2)
- Williams-Thomas, R. et al. 2024. Sexual health and healthy relationships for Further Education (SaFE) in Wales and England: results from a pilot cluster randomised controlled trial. BMJ Open 14, article number: e091355. (10.1136/bmjopen-2024-091355)
- Barry, T. D., Hester, Y., Pallmann, P., Thomas-Jones, E., Underwood, J., Backx, M. and Barry, S. M. 2024. The role of nurses in national TB control programs: qualitative insights from TB cohort review in Wales. Medical Research Archives 12(12) (10.18103/mra.v12i12.6063)
- Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79(11), pp. 2792-2800., article number: dkae246. (10.1093/jac/dkae246)
- Schroeder, E. et al. 2024. The cost-effectiveness and cost-consequences of a school-based social worker intervention: a within-trial economic evaluation. Children and Youth Services Review 166, article number: 107928. (10.1016/j.childyouth.2024.107928)
- Jarvis, R. C., Pallmann, P., Clements, C. and Joshi, H. 2024. Development and preliminary validation of a diagnostic prediction model to optimise outpatient management of patients with urolithiasis using Urinary Stones and Intervention Quality of Life (USIQoL) measure. Quality of Life Research 33, pp. 2809–2818. (10.1007/s11136-024-03733-w)
- Bennett, V. et al. 2024. Student perspectives on school-based social workers: A mixed-methods study. Journal of Children's Services 19(3), pp. 189-221. (10.1108/JCS-04-2023-0021)
- Smith, E. E., Gwilym, B. L., Pallmann, P. and Bosanquet, D. C. 2024. Comment on: "Integrating human intuition into prediction algorithms for improved surgical risk stratification". Annals of Surgery Open 5(3), article number: e485. (10.1097/AS9.0000000000000485)
- Elsmore, A. et al. 2024. The OBS UK Dashboard: an interactive tool for representative trial site selection to facilitate equality and diversity in maternity research. Trials 25, article number: 629. (10.1186/s13063-024-08487-x)
- Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25, article number: 557. (10.1186/s13063-024-08380-7)
- Wood, S. et al. 2024. Family group conference provision in UK local authorities and associations with children looked after rates. The British Journal of Social Work 54(5), pp. 2045-2066. (10.1093/bjsw/bcae019)
- Ioakeimidis, V. et al. 2024. Protocol for a randomised controlled unblinded feasibility trial of HD-DRUM, a rhythmic movement training application for cognitive and motor symptoms in people with Huntington’s disease. BMJ Open 14(7), article number: e082161. (10.1136/bmjopen-2023-082161)
- Naseem, R., Howe, N., Pretorius, S., Williams, C., Lendrem, C., Pallmann, P. and Carrol, E. D. 2024. Mapping decision-making pathways: determination of intervention entry points for diagnostic tests in suspected serious infection. NIHR Open Research 4, article number: 35. (10.3310/nihropenres.13568.1)
- Scourfield, J. et al. 2024. Family group conferencing for children and families: Evaluation of implementation, context and effectiveness (Family VOICE). Study protocol. PLoS ONE 19(6), article number: e0300834. (10.1371/journal.pone.0300834)
- Webb, E. J. D. et al. 2024. Evidence of quality of life for hospitalised patients with COVID-19: a scoping review. Health Technology Assessment (10.3310/ATPR4281)
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8(1), article number: zrad135. (10.1093/bjsopen/zrad135)
- Kumwenda, M. et al. 2024. Identifying critically ill children in Malawi: A modified qSOFA score for low-resource settings. PLOS Global Public Health 4(1), article number: e0002388. (10.1371/journal.pgph.0002388)
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13(12), article number: e077117. (10.1136/bmjopen-2023-077117)
- Metzler-Baddeley, C., Busse-Morris, M., Drew, C., Pallmann, P., Cantera Gomez, J., Ioakeimidis, V. and Rosser, A. 2023. HD-DRUM, a tablet-based drumming training App intervention for people with Huntington Disease: App development study. Journal of Medical Internet Research 2023(7), article number: e48395. (10.2196/48395)
- Law, M. et al. 2023. Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing. Trials 24, article number: 640. (10.1186/s13063-023-07576-7)
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse, M., Godley, M. D. and Griffin, B. A. 2023. A tutorial comparing different covariate balancing methods with an application evaluating the causal effects of substance use treatment programs for adolescents. Health Services and Outcomes Research Methodology 23, pp. 115-148. (10.1007/s10742-022-00280-0)
- Robertson, D. S., Choodari-Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2023. Point estimation for adaptive trial designs II: practical considerations and guidance. Statistics in Medicine 42(14), pp. 2496-2520. (10.1002/sim.9734)
- Karanja, J., Pallmann, P. and Poehling, H. 2023. Systemic slow-release neem formulations: the future of cabbage aphids, Brevicoryne brassicae control. Open Access Library Journal 10, article number: e10158. (10.4236/oalib.1110158)
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
- Potter, C. et al. 2023. Effectiveness and cost-effectiveness of a personalised self-management intervention for living with long covid: protocol for the listen randomised controlled trial. Trials 24, article number: 75. (10.1186/s13063-023-07090-w)
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Llewelyn, M. J., West, R. M., Carrol, E. D., Pallmann, P. and Sandoe, J. A. T. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data - authors' response. Journal of Antimicrobial Chemotherapy 77(11), pp. 3211-3212., article number: dkac315. (10.1093/jac/dkac315)
- Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2022. Point estimation for adaptive trial designs I: A methodological review. Statistics in Medicine (10.1002/sim.9605)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2022. Covariate balancing & weighting web app (COBWEB): an online tool simplifying robust causal inference in observational studies. Journal of Neurology, Neurosurgery and Psychiatry 93(S1), article number: A44. (10.1136/jnnp-2022-ehdn.114)
- Love, S. B. et al. 2022. Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units. Trials 23, article number: 757. (10.1186/s13063-022-06680-4)
- Wason, J. M. S. et al. 2022. Practical guidance for planning resources required to support publicly‑funded adaptive clinical trials. BMC Medicine 20, article number: 254. (10.1186/s12916-022-02445-7)
- Morgan-Jones, P. et al. 2022. Monitoring and managing lifestyle behaviours using wearable activity trackers: a mixed methods study of views from the Huntington's disease community. JMIR Formative Research 6(6), article number: e36870. (10.2196/36870)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Westlake, D. et al. 2022. The SWIS trial: protocol of a pragmatic cluster randomised controlled trial of school based social work. PLoS ONE 17(6), article number: e0265354. (10.1371/journal.pone.0265354)
- Llewelyn, M. J. et al. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77(4), pp. 1189-1196. (10.1093/jac/dkac017)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
- Powell, E., James, D., Collis, R., Collins, P., Pallmann, P. and Bell, S. 2022. Introduction of standardized, cumulative quantitative measurement of blood loss into routine maternity care. Journal of Maternal-Fetal and Neonatal Medicine 35(8), pp. 1491-1497. (10.1080/14767058.2020.1759534)
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
- Wilson, N. et al. 2021. Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project. BMC Medicine 19, article number: 251. (10.1186/s12916-021-02124-z)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Romaine, S. T. et al. 2021. Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open 11(5), article number: e044091. (10.1136/bmjopen-2020-044091)
- Bell, S. F. et al. 2021. Reduction in massive postpartum haemorrhage and red blood cell transfusion during a national quality improvement project, Obstetric Bleeding Strategy for Wales, OBS Cymru: an observational study. BMC Pregnancy and Childbirth 21, article number: 377. (10.1186/s12884-021-03853-y)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
- Wheeler, M., Powell, E. and Pallmann, P. 2021. Use of high-fidelity simulation training for radiology healthcare professionals in the management of acute medical emergencies. British Journal of Radiology 94(1117), article number: 20200520. (10.1259/bjr.20200520)
- Drew, C. et al. 2021. Protocol for an open label, phase I trial within a cohort of fetal cell transplants in people with Huntington’s disease. Brain Communications 3(1), article number: fcaa230. (10.1093/braincomms/fcaa230)
- Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. and Jaki, T. 2020. Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs. BMC Medicine 18, article number: 352. (10.1186/s12916-020-01808-2)
- Romaine, S. T. et al. 2020. Accuracy of a modified qSOFA score for predicting critical care admission in febrile children. Pediatrics 146(4), article number: e20200782. (10.1542/peds.2020-0782)
- Dimairo, M. et al. 2020. The Adaptive designs CONSORT Extension (ACE) Statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ 369, article number: m115. (10.1136/bmj.m115)
- Dimairo, M. et al. 2020. The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 21, article number: 528. (10.1186/s13063-020-04334-x)
- Pallmann, P. et al. 2020. Designing and evaluating dose-escalation studies made easy: the MoDEsT web app. Clinical Trials 17(2), pp. 147-156. (10.1177/1740774519890146)
- Hornbacher, J., Rumlow, A., Pallmann, P., Turcios, A. E., Riemenschneider, A. and Papenbrock, J. 2019. The levels of sulfur-containing metabolites in Brassica napus are not influenced by the circadian clock but diurnally. Journal of Plant Biology 62(5), pp. 359-373. (10.1007/s12374-019-0143-x)
- Drew, C. J. G. et al. 2019. A protocol for a randomised controlled, double-blind feasibility trial investigating fluoxetine treatment in improving memory and learning impairments in patients with mesial temporal lobe epilepsy: Fluoxetine, Learning and Memory in Epilepsy (FLAME trial). Pilot and Feasibility Studies 5(1), article number: 87. (10.1186/s40814-019-0474-x)
- Jansen, J. O., Pallmann, P., MacLennan, G. and Campbell, M. K. 2019. Bayesian clinical trial designs another option for trauma trials? Erratum. Journal of Trauma and Acute Care Surgery 86(4), pp. 760. (10.1097/TA.0000000000002236)
- Jaki, T., Pallmann, P. and Magirr, D. 2019. The R package MAMS for designing multi-arm multi-stage clinical trials. Journal of Statistical Software 88(4)
- Dimairo, M. et al. 2018. Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design. BMC Medicine 16(1), article number: 210. (10.1186/s12916-018-1196-2)
- Pallmann, P., Ritz, C. and Hothorn, L. A. 2018. Simultaneous small-sample comparisons in longitudinal or multi-endpoint trials using multiple marginal models. Statistics in Medicine 37(9), pp. 1562-1576. (10.1002/sim.7610)
- Pallmann, P. et al. 2018. Adaptive designs in clinical trials: why use them, and how to run and report them. BMC Medicine 16, article number: 29. (10.1186/s12916-018-1017-7)
- Pallmann, P. and Jaki, T. 2017. Simultaneous confidence regions for multivariate bioequivalence. Statistics in Medicine 36(29), pp. 4585-4603. (10.1002/sim.7446)
- Pallmann, P., Pretorius, M. and Ritz, C. 2017. Simultaneous comparisons of treatments at multiple time points: Combined marginal models versus joint modeling. Statistical Methods in Medical Research 26(6), pp. 2633-2648. (10.1177/0962280215603743)
- Jansen, J. O., Pallmann, P., MacLennan, G. and Campbell, M. K. 2017. Bayesian clinical trial designs: Another option for trauma trials?. Journal of Trauma and Acute Care Surgery 83(4), pp. 736-741. (10.1097/TA.0000000000001638)
- Parkes, M., Lunt, M., Pallmann, P. and Felson, D. T. 2017. The two-stage treatment selection (TSTS) design: a novel approach to treatment selection in clinical trials. Trials 18(S1), pp. 166., article number: P440. (10.1186/s13063-017-1902-y)
- Otieno, J. A., Pallmann, P. and Poehling, H. 2017. Additive and synergistic interactions amongst Orius laevigatus (Heteroptera: Anthocoridae), entomopathogens and azadirachtin for controlling western flower thrips (Thysanoptera: Thripidae). BioControl 62(1), pp. 85-95. (10.1007/s10526-016-9767-7)
- Pallmann, P. 2017. Sample size determination in clinical trials with multiple endpoints. T. Sozu, R. Sugimoto, T. Hamasaki, and S. R. Evans (2015). New York, NY: Springer. 95 pages, ISBN: 978-3-319-22004-8. Biometrical Journal 59(1), pp. 218. (10.1002/bimj.201600135)
- Rumlow, A., Keunen, E., Klein, J., Pallmann, P., Riemenschneider, A., Cuypers, A. and Papenbrock, J. 2016. Quantitative expression analysis in brassica napus by northern blot analysis and reverse transcription-quantitative PCR in a complex experimental setting. PLoS ONE 11(9), article number: e0163679. (10.1371/journal.pone.0163679)
- Pallmann, P. and Hothorn, L. A. 2016. Boxplots for grouped and clustered data in toxicology. Archives of Toxicology 90(7), pp. 1631-1638. (10.1007/s00204-015-1608-4)
- Otieno, J. A., Pallmann, P. and Poehling, H. -. 2016. The combined effect of soil-applied azadirachtin with entomopathogens for integrated management of western flower thrips. Journal of Applied Entomology 140(3), pp. 174-186. (10.1111/jen.12242)
- Pallmann, P. and Hothorn, L. A. 2016. Analysis of means: a generalized approach using R. Journal of Applied Statistics 43(8), pp. 1541-1560. (10.1080/02664763.2015.1117584)
- Pallmann, P. and Schaarschmidt, F. 2016. Common pitfalls when testing additivity of treatment mixtures with chi-square analyses. Journal of Applied Entomology 140(1-2), pp. 135-141. (10.1111/jen.12258)
- Pallmann, P. 2015. Simultaneous Statistical Inference: With Applications in the Life Sciences. T.Dickhaus (2014). Heidelberg: Springer. 180 pages, ISBN: 978-3-642-45181-2.. Biometrical Journal 57(6), pp. 1151-1152. (10.1002/bimj.201500129)
- Pallmann, P. 2015. Analyzing baseball data with R [book review]. Journal of the Royal Statistical Society Series A (Statistics in Society) 178(4), pp. 1099-1099. (10.1111/rssa.3_12138)
- Karanja, J., Poehling, H. and Pallmann, P. 2015. Efficacy and dose response of soil-applied neem formulations in substrates with different amounts of organic matter, in the control of whiteflies, aleyrodes proletella and trialeurodes vaporariorum (hemiptera: aleyrodidae). Journal of Economic Entomology 108(3), pp. 1182-1190. (10.1093/jee/tov047)
- Weese, A., Pallmann, P., Papenbrock, J. and Riemenschneider, A. 2015. Brassica napus L. cultivars show a broad variability in their morphology, physiology and metabolite levels in response to sulfur limitations and to pathogen attack. Frontiers in Plant Science 6, article number: 9. (10.3389/fpls.2015.00009)
- Pallmann, P., Hothorn, L. A. and Djira, G. D. 2014. A Levene-type test of homogeneity of several variances against ordered alternatives. Computational Statistics 29, pp. 1593-1608. (10.1007/s00180-014-0508-z)
- Pallmann, P. 2014. Applied meta-analysis with R. Journal of Applied Statistics 42(4), pp. 914-915. (10.1080/02664763.2014.989464)
- Jaki, T., Pallmann, P. and Wolfsegger, M. J. 2013. Estimation in AB/BA crossover trials with application to bioequivalence studies with incomplete and complete data designs. Statistics in Medicine 32(30), pp. 5469-5483. (10.1002/sim.5886)
- Jaki, T., Pallmann, P. and Wolfsegger, M. J. 2013. Authors' reply to Comments on 'Estimation in AB/BA crossover trials with application to bioequivalence studies with incomplete and complete data designs'. Statistics in Medicine 32(30), pp. 5487-5488. (10.1002/sim.6000)
- Pallmann, P., Schaarschmidt, F., Hothorn, L. A., Fischer, C., Nacke, H., Priesnitz, K. U. and Schork, N. J. 2012. Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices. Molecular Ecology Resources 12(6), pp. 1068-1078. (10.1111/1755-0998.12004)
Gwefannau
- Robertson, D. S., Burnett, T., Choodari-Oskooei, B., Dimairo, M., Grayling, M., Pallmann, P. and Jaki, T. 2024. Confidence intervals for adaptive trial designs I: a methodological review. [Online]. arXiv: Cornell University. (10.48550/arXiv.2411.08495) Available at: https://doi.org/10.48550/arXiv.2411.08495
- Robertson, D. S., Burnett, T., Choodari-Oskooei, B., Dimairo, M., Grayling, M., Pallmann, P. and Jaki, T. 2024. Confidence intervals for adaptive trial designs II: case study and practical guidance. [Online]. arXiv: Cornell University. (10.48550/arXiv.2411.08771) Available at: https://doi.org/10.48550/arXiv.2411.08771
- Schroeder, E. et al. 2024. The cost-effectiveness and cost-consequences of a school-based social worker intervention: a within-trial economic evaluation. [Online]. SSRN. (10.2139/ssrn.4776734)
- Ioakeimidis, V. et al. 2023. Protocol for a randomised controlled feasibility trial of HD-DRUM, a rhythmic movement training application for cognitive and motor symptoms in people with Huntington's disease. [Online]. medRxiv: medRxiv. (10.1101/2023.11.15.23298581) Available at: https://doi.org/10.1101/2023.11.15.23298581
- Metzler-Baddeley, C., Busse, M., Drew, C., Pallmann, P., Cantera Gomez, J., Ioakeimidis, V. and Rosser, A. E. 2023. Applying an integrated knowledge translation framework approach to develop a tablet-based rhythmic movement training intervention for people with Huntington’s disease. [Online]. JMIR Preprints. (10.2196/preprints.48395) Available at: https://preprints.jmir.org/preprint/48395
- Dimairo, M. et al. 2022. PANDA: a practical adaptive and novel designs and analysis toolkit. [Online]. University of Sheffield. Available at: https://panda.shef.ac.uk/
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. CoBWeb: a user-friendly web application to estimate causal treatment effects from observational data using multiple algorithms. [Online]. Cornell University. Available at: https://arxiv.org/abs/2112.05035
- Robertson, D. S., Choodari-Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. and Jaki, T. 2021. Point estimation for adaptive trial designs. [Online]. Cornell University. Available at: https://arxiv.org/abs/2105.08836
- Markoulidakis, A., Holmans, P., Pallmann, P., Busse, M. and Griffin, B. A. 2021. How balance and sample size impact bias in the estimation of causal treatment effects: a simulation study. [Online]. Cornell University. Available at: https://arxiv.org/abs/2107.09009
- Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. and Jaki, T. 2020. Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs. [Online]. arXiv. Available at: https://arxiv.org/abs/2006.12811
- Markoulidakis, A., Taiyari, K., Holmans, P., Pallmann, P., Busse-Morris, M. and Griffin, B. A. 2020. A tutorial comparing different covariate balancing methods with an application evaluating the causal effect of exercise on the progression of Huntington’s disease. [Online]. arXiv. Available at: https://arxiv.org/abs/2010.09563
Monograffau
- Adara, L. et al. 2023. The Social Workers in Schools Trial: An evaluation of school based social work.. Project Report. Early Intervention Foundation.
- Wood, S. et al. 2022. A UK-wide survey of family group conference provision. Project Report. Cardiff: CASCADE.
- Bell, S. F. et al. 2021. Reduction in massive postpartum haemorrhage and red blood cell transfusion during a national quality improvement project, Obstetric Bleeding Strategy for Wales, OBS Cymru: an observational study (October 11, 2020). Working paper. SSRN: SSRN. Available at: http://doi.org/10.2139/ssrn.3746928
Ymchwil
Crynodeb o'm hymchwil
Ar hyn o bryd rwy'n gweithio ar nifer o dreialon clinigol (CLARITY, DocTIS, HD-DRUM, OBS UK, PLACEMENT®, PRONTO, SParky Samba, TIPTOEe) ac astudiaethau arsylwadol (Llais Teulu). Mae astudiaethau blaenorol yr wyf wedi gweithio arnynt yn cynnwys BATCH, DOMINO-HD, FLAME, LISTEN, PEACH, PERCEIVE, PRECISE, PROTECT (prif ymchwilydd), SaFE, SWIS, TAPERS, a TRIDENT®.
Rwyf wedi bod yn cymryd rhan weithredol ym Mhrosiect ACE i ddatblygu estyniad CONSORT swyddogol ar gyfer treialon clinigol gyda dyluniad addasol, Prosiect PANDA i greu platfform ar-lein addysgol am ddyluniadau addasol, Prosiect CAT i ddatblygu arfer gorau sy'n costio canllawiau ar gyfer CTUs sy'n cefnogi treialon dylunio addasol, a Phrosiect ROBIN i ddatblygu canllawiau arfer gorau ar gyfer cynnal dadansoddiadau interim mewn treialon cam hwyr.
Rwyf hefyd yn cymryd rhan mewn nifer o brosiectau cymrodoriaeth gan gynnwys fel cydweithredwr a ariennir ar Gymrodoriaeth Uwch HCRW/NIHR Claudia Metzler-Baddeley, fel cynghorydd ar Gymrodoriaeth Datblygu Gyrfa CRUK Haiyan Zheng, ac fel cyd-oruchwyliwr ar Gymrodoriaeth Gynddoethurol NIHR Joseph Caldwell.
Rwyf wedi ysgrifennu (cyd) a / neu rwy'n cynnal nifer o becynnau R sydd ar gael yn rhwydd ar CRAN®, gan gynnwys MAMS (astudiaethau aml-gam aml-fraich), BayesMAMS (astudiaethau aml-gam aml-fraich Bayesaidd), jocre (rhanbarthau cyd-hyder), cymedrol (treialon cynyddu dosau sy'n seiliedig ar fodel), ANOM (dadansoddi modd), a simboot (casgliad ar y pryd ar gyfer mynegeion amrywiaeth).
Rhwng 2017 a 2023 roeddwn yn Ddirprwy Gyfarwyddwr y Gwasanaeth Dylunio ac Ymddygiad Ymchwil (RDCS) ar gyfer De-ddwyrain Cymru, a fu'n gweithio gyda'r GIG a staff gofal cymdeithasol i ddatblygu ceisiadau cyllid o ansawdd uchel ar gyfer prosiectau ymchwil arloesol ym maes iechyd a gofal cymdeithasol.
Dyfarnwyd cyllid grant yn ddiweddar
2024
- JGGF NRG: Gwerthuso dichonoldeb ymyrraeth taro samba ar gyfer pobl â chlefyd Parkinson (SParky Samba) (£360,881)
2023
- NIHR HTA: Hap-dreial sy'n archwilio effeithiolrwydd clinigol a chost tri chyfundrefn wrththrombotig yn dilyn ail-fasgwleiddio aelodau isaf endofasgwlaidd ar gyfer ischaemia cronig sy'n bygwth aelodau: CLARITY (clopidogrel, aspirin a rivaroxaban ar ôl ail-fasgwleiddio gydag angioplasti) (£2,575,967)
- NIHR HTA: Gwerthuso ar hap platfform o ganlyniadau clinigol gan ddefnyddio technolegau newydd i optimeiddio therapi gwrthficrobaidd (PROTECT®) (£204,987, Prif Ymchwilydd)
2022
- NIHR HSDR: Clinigol a chost-effeithiolrwydd rhaglen gwella ansawdd mamolaeth i leihau gwaedu gormodol a'r angen am drallwysiad ar ôl genedigaeth: camodd astudiaeth gwaedu obstetrig y DU (OBS UK) dreial ar hap clwstwr lletem (£3,650,790)
- NIHR HTA: Hunanreolaeth aml-barth mewn pobl hŷn sydd ag osteoarthritis ac aml-afiachedd (TIPTOE) (£1,711,355)
- NIHR CTU Cymorth Cyllid: Eirioliadau cadarn ar gyfer dyluniadau addasol (ROBIN): datblygu arfer gorau ar gyfer dadansoddiadau interim o ansawdd uchel a chyflym mewn treialon cam II-IV (£71,238)
- NIHR HTA: catheter anesthetig lleol perineural ar ôl torri aelodau isaf (PLACEMENT) (PLACEMENT®) (£1,635,918)
2021
- NIHR Long COVID galwad: Cymorth hunanreoli personol COVID hir – cyd-ddylunio a gwerthuso (LISTEN) (£1,055,520)
- NIHR & DR: Cynadledda grŵp teulu ar gyfer plant a theuluoedd: gwerthuso gweithredu, cyd-destun ac effeithiolrwydd (Llais y Teulu) (£1,194,736)
2020
- NIHR HTA: Procalcitonin: gwerthuso defnydd gwrthfiotig mewn cleifion ysbyty COVID-19 (PEACH) (£731,858)
- HCRW RfPPB: PERCEIVE: rhagfynegi risg a chyfathrebu canlyniad yn dilyn torri aelodau isaf mawr – astudiaeth gydweithredol (£229,225)
- DfE WWCSC: Gweithwyr cymdeithasol mewn ysgolion sy'n cynyddu (SWIS) (£385,597)
- NIHR EME: MR-pro-adrenomedullin (MR-proADM) a gwerthusiad ImmunoXpert o hyd gwrthfiotig dan arweiniad procalcitonin mewn plant sydd â haint ar gyfer haenu effeithiolrwydd (PRECISE) (£385,450)
2019
- Cyllid Seilwaith HCRW CTU: Y Ganolfan Treialon Ymchwil 2020-23 (£2,470,489)
- Cyllid Cymorth CTU NIHR: Costau treialon addasol (CAT): datblygu arfer gorau sy'n costio canllawiau ar gyfer CTUs sy'n cefnogi treialon addasol (£55,629)
- NIHR HTA: Gwerthusiad Procalcitonin a NEWYDDION ar gyfer adnabod sepsis yn amserol a'r defnydd gorau posibl o wrthfiotigau yn yr adran frys (PRONTO) (£1,968,786)
- NIHR: Optimeiddio, profi dichonoldeb a threial peilot ar hap o SaFE: ymyrraeth iechyd rhywiol a pherthnasoedd iach ar gyfer addysg bellach (£510,815)
- H2020 yr UE: Penderfyniad ar therapïau cyfunol gorau posibl mewn IMIDs gan ddefnyddio dulliau systemau (DocTIS) (€ 6,260,050)
2018
- Ymchwil JPND yr UE: Targedau ffordd o fyw aml-barth ar gyfer gwella prognosis mewn clefyd Huntington (DOMINO-HD) (€ 2,057,969)
- Cyllid Cymorth CTU NIHR: Pecyn cymorth dylunio addasol a newydd ymarferol (PANDA) (£98,886)
- HCRW RfPPB: Trin pryder er mwyn atal llithro mewn sgitsoffrenia (TAPERS) – treial dichonoldeb (£229,865)
Bywgraffiad
Addysg a chymwysterau
- 2016: PhD Bioystadegau, Leibniz Universität Hannover
- 2012: MSc Biotechnoleg Planhigion, Leibniz Universität Hannover
- 2010: BSc Biotechnoleg Planhigion, Leibniz Universität Hannover
Anrhydeddau a dyfarniadau
- 2023: Gwobr adolygydd cymheiriaid y flwyddyn am y Journal of Clinical Epidemiology
- 2013: Gwobr Bernd Streitberg o'r Gymdeithas Biometreg Ryngwladol (Rhanbarth yr Almaen) am fy nhraethawd hir MSc Profion dau sampl a phrofion cyferbyniad lluosog o sawl mynegai amrywiaeth
-
2012: Ail Wobr am y Cyflwyniad Llafar Myfyrwyr Gorau yn y 36ain Cynhadledd Biometrig Ryngwladol yn Kobe, Japan
Aelodaethau proffesiynol
- Cyd-arweinydd y Gweithgor Dyluniadau Addasol, Partneriaeth Ymchwil Methodoleg Treialon MRC-NIHR (yn flaenorol: MRC Network of Hubs for Trials Methodology Research)
- Aelod o Rwydwaith Clefyd Huntington Ewrop
Safleoedd academaidd blaenorol
- 2024 - presennol: Prif Gymrawd Ymchwil, Canolfan Treialon Ymchwil, Prifysgol Caerdydd
- 2022 - 2024: Uwch Gymrawd Ymchwil, Canolfan Treialon Ymchwil, Prifysgol Caerdydd
- 2017 - 2023: Dirprwy Gyfarwyddwr RDCS, Canolfan Ymchwil Treialon Prifysgol Caerdydd
- 2017 - 2022: Cymrawd Ymchwil, Canolfan Treialon Ymchwil, Prifysgol Caerdydd
- 2015 - 2017: Uwch Gydymaith Ymchwil, Adran Mathemateg ac Ystadegau, Prifysgol Lancaster
- 2012 - 2015: Cydymaith Ymchwil , Sefydliad Bioystadegau, Leibniz Universität Hannover
- 2010 - 2012: Cynorthwy-ydd Ymchwil, Sefydliad Bioystadegau, Leibniz Universität Hannover
- 2009 - 2010: Cynorthwy-ydd Addysgu, Sefydliad Clefydau Planhigion a Diogelu Planhigion, Leibniz Universität Hannover
Ymrwymiadau siarad cyhoeddus
Cyflwyniadau Cynhadledd (dewisol)
- Heriau dylunio a chyflwyno treial ar hap clystyrau stepped-lletem o bwndel ymyrraeth cymhleth mewn gofal mamolaeth gan ddefnyddio data gofal iechyd a gesglir fel mater o drefn. 9fed cyfarfod blynyddol ar ddatblygiadau cyfredol mewn treialon ar hap clwstwr a dyluniadau lletem cam, Llundain, y DU. 9 Tachwedd 2023. Cyd-awduron: Sarah Kotecha, Julia Townson, Dimitrios Profer, Amy Elsmore, William Parry-Smith, Peter Collins, Sarah Bell.
- Mae treial yn dylunio gyda rhagoriaeth gyd-gynradd a diweddbwyntiau nad ydynt yn israddol: pwyntiau trafod methodolegol a chanllawiau ymarferol. Cynhadledd Methodoleg Treialon Clinigol Rhyngwladol 6ed, Harrogate, y DU. 5 Hydref 2022. Cyd-awduron: Simon Schoenbuchner, Abin Thomas, David Gillespie.
- Rhanbarthau hyder ar yr un pryd ar gyfer bioequivalence aml-baramedr. 62ain Biometrisches Kolloquium & DAGStat, Göttingen, Yr Almaen. 18 Mawrth 2016. Cyfarwyddwr: Thomas Jaki
- Profion cyferbyniad lluosog gyda data hydredol. Cynhadledd Ryngwladol ar Gasgliad ar y pryd, Hannover, yr Almaen. 25 Medi 2013.
- Sefydlu bioequivalence mewn treialon traws-dros-dro AB/BA gan ddefnyddio'r gymhareb o AUCs a amcangyfrifir o ddyluniadau samplu bras. 59fed Biometrisches Kolloquium & DAGStat, Freiburg, Yr Almaen. 19 Mawrth 2013. Llenyddiaeth: Thomas Jaki, Martin J Wolfsegger
- Cymharu bioamrywiaeth drwy brofi detholiad o fynegeion amrywiaeth a ddiffiniwyd gan y defnyddiwr ar yr un pryd. 36ain Cynhadledd Biometrig Ryngwladol, Kobe, Japan. 30 Awst 2012.
- Cymharu bioamrywiaeth drwy brofi detholiad o fynegeion amrywiaeth a ddiffiniwyd gan y defnyddiwr ar yr un pryd. 58fed Biometrisches Kolloquium, Berlin, yr Almaen. 14 Mawrth 2012.
Posteri cynhadledd (dewiswyd)
- Ehangiad dos effeithlon sy'n seiliedig ar fodel ar flaenau eich bysedd: offeryn meddalwedd syml i ddylunio a gwerthuso treialon canser cam I. Cynhadledd Canser NCRI, Lerpwl, y DU. 6 Tachwedd 2017. Cyd-awduron: Fang Wan, Christina Yap, Adrian P Mander, Graham M Wheeler, Sally Clive, Thomas Jaki, Lisa V Hampson.
- Dylunio treialon aml-gam aml-fraich gyda'r pecyn R 'MAMS'. Cynhadledd PSI, Berlin, yr Almaen. 23 Mai 2016. Cyd-awduron: Thomas Jaki, Dominic Magirr.
- Dadansoddiad o ddulliau gyda'r pecyn R 'ANOM'. 62ain Biometrisches Kolloquium & DAGStat, Göttingen, Yr Almaen. 16 Mawrth 2016. Cyd-awdur: Ludwig A Hothorn.
- Casgliad sampl fach ar yr un pryd mewn lleoliadau hydredol gan ddefnyddio cyferbyniadau lluosog. 60fed Biometrisches Kolloquium, Bremen, yr Almaen. 12 Mawrth 2014.
Pwyllgorau ac adolygu
Pwyllgorau goruchwylio allanol
- Aelod o Bwyllgor Llywio Treialon Annibynnol: NOTACS, TIP2, INTERACT, TREADON, FAITH (ar hyn o bryd); MODIWLEIDDIO, TIP, CYNLLUN-A, AML18/19 / LI1 (yn flaenorol)
- Aelod o'r Pwyllgor Monitro Data Annibynnol/Bwrdd Monitro Diogelwch Data: TRAITS, TRICEPS, ECRAID-Prime, SABRE, DETECT (ar hyn o bryd); ABC Sepsis, CANTOP-RhCT (yn flaenorol)
Pwyllgorau cyllido
- Aelod o'r pwyllgor cyllido ar gyfer Cymrodoriaethau Uwch MRC-NIHR EME (ers 2024)
- Aelod o'r pwyllgor cyllido ar gyfer MRC-NIHR EME (ers 2022)
- Aelod Cyfadran yr Arbenigwyr ar gyfer galwad UKRI MRC AGHRB "Astudiaethau gweithredu brechlyn malaria yn Affrica" (2024)
- Aelod o bwyllgor cyllido cyswllt ar gyfer NIHR HTA (2021-2022)
Dyletswyddau golygyddol
- Golygydd Cyswllt Treialon
Adolygu
- Adolygydd cais am grant ar gyfer NIHR (HTA, PHR, HS&DR), MRC (BMC DPFS, Better Methods Better Research), MRC-NIHR (EME, Rhaglen Ymchwil Methodoleg), HRB TMRN/MRC-NIHR TMRP (Cyd-ariannu Prosiect Sbarduno Gweithgor), UKRI (Cymrodoriaeth Arweinwyr y Dyfodol), HCRW (Ysgoloriaeth Iechyd PhD, Llwybr i Bortffolio), Blood Cancer UK yn ogystal ag yn rhyngwladol (DFG - Sefydliad Gwyddoniaeth yr Almaen; NCN - Canolfan Wyddoniaeth Genedlaethol Gwlad Pwyl; ZonMW - Sefydliad yr Iseldiroedd ar gyfer Ymchwil a Datblygu Iechyd; Inserm - Sefydliad Cenedlaethol Iechyd ac Ymchwil Feddygol Ffrainc)
- Adolygydd adroddiad terfynol ar gyfer NIHR (HTA, PHR)
- Adolygydd crynodeb cynhadledd ar gyfer 38ain Cyfarfod Blynyddol ESPID 2020, ICTMC 2022, ICTMC 2024, SAPC ASM 2025
- Adolygydd cynigion llyfrau ar gyfer Gwasg Prifysgol Caergrawnt
- Adolygydd llawysgrif ar gyfer cyfnodolion gan gynnwys Ystadegau mewn Meddygaeth, Journal of Statistical Software, Biometrical Journal, The American Statistician, Journal of the American Statistical Association, Dulliau Ystadegol mewn Ymchwil Feddygol, Papurau Ystadegol, Ystadegau, Stat, Journal of Applied Statistics, Journal of Biopharmaceutical Statistics, Cyfathrebu mewn Ystadegau - Efelychu a Chyfrifiadur, Journal of Statistical Computation and Simulation, Journal of Computational and Graphical Ystadegau, Statistica Neerlandica, Cyfnodolyn Epidemioleg Glinigol, Cyfnodolyn Meddalwedd Ffynhonnell Agored, Modelau Stocastig Cymhwysol mewn Busnes a Diwydiant, BMJ Agored, PLOS One, Gwyddoniaeth Agored y Gymdeithas Frenhinol, Adroddiadau Gwyddonol, PeerJ, Treialon, Treialon Clinigol, Treialon Clinigol Cyfoes, Gwyddoniaeth Gweithredu, Cyfnodolyn Canser Prydain, Cyfnodolyn Heintio, Journal of HospitalInfection, Cyfnodolyn Cymdeithas Neffroleg America, Ffiniau mewn Niwroleg, BMJ Nutrition Prevention & Health, Trallwysiad, Cyfnodolyn Meddygaeth Glinigol, eBioMedicine, Adolygiad Arbenigol o Therapi Gwrth-Heintus, Microbioleg Diagnostig a Chlefydau Heintus, Cyfathrebu Natur , Adolygiadau Natur Darganfod Cyffuriau, Nature Human Behaviour, The AAPS Journal, The British Student Doctor Journal, Rhyngrwyd y Dyfodol, Gwyddoniaeth yr Amgylchedd ac Ymchwil Llygredd, Gwyddoniaeth Rheoli Plâu (gweler fy mhroffil Publons)
Meysydd goruchwyliaeth
Goruchwyliaeth gyfredol
Tamas Barry
Malavika Babu
Prosiectau'r gorffennol
- Cyd-oruchwyliwr Joseph Caldwell (Prifysgol Caerhirfryn) – amcangyfrif diduedd a llai rhagfarnllyd mewn treialon addasol gyda diweddbwyntiau cyd-gynradd cydberthynol ac anghyson yng nghyd-destun treial clinigol PRONTO (MSc Ystadegau, 2024, gyda Fang Wan)
- Cyd-oruchwyliwr Andreas Markoulidakis – Dulliau ystadegol ar gyfer nodi a modelu ffactorau ffordd o fyw sy'n gysylltiedig â difrifoldeb a dilyniant clefyd Huntington (PhD, 2024, gyda Peter Holmans, Monica Busse, a Beth Ann Griffin)
- goruchwyliwr arweiniol ar gyfer Kittinan Praesertrungrueang – Datblygu a phrofi offeryn darogan newydd ar gyfer canlyniadau clinigol yn dilyn torri aelodau isaf mawr (MSc Gwyddor Data a Dadansoddeg, 2023, gyda David Bosanquet a Brenig Gwilym)
- Cyd-oruchwyliwr William Blake – Cymhwyso technegau casgliadau achosol i amcangyfrif effaith newidynnau ffordd o fyw ar ddifrifoldeb clefyd Huntington (MSc Ymchwil Gweithredol ac Ystadegau Cymhwysol, 2022, gydag Andreas Markoulidakis a Monica Busse)
- Cyd-oruchwyliwr Saif Abbas Chatoo – presgripsiynu gwrthfiotig mewn cleifion ysbyty gyda COVID-19 fel swyddogaeth o farcwyr llidiol yn nhon 1 yn erbyn ton 2: adolygiad systematig (Rhyng-gyfrifedig BSc Meddygaeth Poblogaeth, 2022, gyda Joanne Euden ac Emma Thomas-Jones)
Goruchwylio presennol (allanol)
- Cyd-oruchwyliwr ar gyfer Joseph Caldwell (Prifysgol Lancaster) – Dyluniadau treial llwyfan addasol ar gyfer ymchwil stiwardiaeth gwrthficrobaidd (Cymrodoriaeth Cynddoethurol NIHR, gyda Fang Wan)
Arholiad PhD
- Arholwr allanol ar gyfer Aritra Mukherjee (Prifysgol Newcastle)
- Arholwr mewnol ar gyfer Genevieve Meier
Contact Details
PallmannP@caerdydd.ac.uk
+44 29206 87461
Neuadd Meirionnydd, Ystafell 505, 5ed llawr, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
+44 29206 87461
Neuadd Meirionnydd, Ystafell 505, 5ed llawr, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
Arbenigeddau
- Ystadegau
- Ystadegau cymhwysol
- Ymchwil clinigol cymhwysol
- Gofal sy'n seiliedig ar dystiolaeth