Organic Synthesis
We have developed a particular strength in Organic Synthesis, with a research group dedicated to this exciting area of study. As part of the Chemistry (PhD/MPhil) programme, students can conduct their research within this group.
Our Organic Synthesis research group largely focuses on the development of novel synthetic methods and applications of these in target synthesis, most often either natural products or biologically active compounds of pharmaceutical or agrochemical significance. In many cases, the inspiration for developing the new methodology arises from a consideration of the structural features of such targets.
Areas of current interest are:
- main group chemistry catalysis using iodine, boron, and aluminium reagents
- electrochemical reactions as an environmentally friendly technology
- reactions in flow systems
- synthesis of energetic materials
Driven by the demands of industry and environmental considerations, much of our work is aimed at defining new methods for the highly efficient and catalytic generation of such compounds. A particularly strong theme is the formation of such compounds by the electrophile-driven addition of nucleophiles to unsaturated carbon-carbon bonds.
Organocatalysis, an increasingly important area given the toxicity of many transition metals, is well-represented within our group. Current target types include complex polycyclic peptides, alkaloids, steroids, terpene alkaloids and plant-derived oxygen heterocycles.
Our research group has strong interdisciplinary collaborations in the UK and worldwide. Our project links with international institutions can lead to students having placements abroad.
Contacts
Administrative contact(s)
Dr Ben Ward
Administrative contact
Research groups within the area of Organic Chemistry are active in the design of new reactions, and the application of reactions towards challenging target molecules combined with thorough investigations of the reaction mechanisms. The research in Organic Chemistry is interfacing and connected to other scientific areas, including other chemistry sub-disciplines such as biological and materials chemistry, physics, engineering, and medical research.
In particular, research groups are investigating main group chemistry such as halogen and chalcogen chemistry, but also chemistry around boron and aluminium. Fundamental studies also develop new catalytic reactions. The research is often supported by computational studies in a synergistic combination of theory and experiment. The research involves close collaboration with colleagues in other research groups within the department.
Groups within the organic research at Cardiff are interested in the development of synthetic methodologies. For example, flow chemistry and electrochemistry are techniques which are applied towards the synthesis of natural products or energetic materials. Several aspects of such work are also undertaken in close collaboration and with sponsorship from industry.
Research using radionuclides in organic synthesis is directly interfacing with clinical medicine.
Our research pushes the boundaries of what is possible and is inherently interdisciplinary, involving collaborations with experts in fields ranging from physical chemistry to biology or technologies underpinning sustainable and environmentally friendly approaches towards organic synthesis.
PGR supervisors working in this area include:
Projects
We have an extensive list of research projects that our supervisors are currently working on and we welcome applicants interested in these projects.
Applicants for these projects do need to have secured funding for themselves. This could be from external sponsors, student loans or self-funding.
In addition to this, we have a range of research projects with external funding. Check that you meet any specific funding eligibility criteria before applying.
You are welcome to contact the academics directly for an informal chat, or further information.
All applications should be made via the Cardiff University application service.
Funding
You can search our studentships or find out more about funding.
Tuition fees
Students from the UK
Get the latest information on postgraduate fees.
Students from the EU, EEA and Switzerland
Get the latest information on postgraduate fees.
Students from the rest of the world (international)
Programme information
For programme structure, entry requirements and how to apply, visit the Chemistry programme.
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