Julia Grimstead

2023

• Roger, L., Miners, K. L., Leonard, L., Grimstead, J. W., Price, D. A., Baird, D. M. and Ladell, K. 2023. T cell memory revisited using single telomere length analysis. Frontiers in Immunology 14, article number: 1100535. (10.3389/fimmu.2023.1100535)

2022

• Geiller, H. E., Harvey, A., Jones, R. E., Grimstead, J. W., Cleal, K., Hendrickson, E. A. and Baird, D. 2022. ATRX modulates the escape from a telomere crisis. Plos Genetics 18(11), article number: e1010485. (10.1371/journal.pgen.1010485)

2021

• Garcia Martin, I., Penketh, R. J. A., Garay, S. M., Jones, R. E., Grimstead, J. W., Baird, D. M. and John, R. M. 2021. Symptoms of prenatal depression associated with shorter telomeres in female placenta. International Journal of Molecular Sciences 22(14), article number: 7458. (10.3390/ijms22147458)
• Norris, K. et al. 2021. High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders. Human Genetics 140, pp. 945-955. (10.1007/s00439-021-02257-4)
• Ngo, G. H. P., Grimstead, J. W. and Baird, D. M. 2021. UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair. Nature Communications 12, article number: 3849. (10.1038/s41467-021-24201-w)
• Liddiard, K., Grimstead, J., Cleal, K., Evans, A. and Baird, D. 2021. Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA Damage Response. NAR Cancer 3(1), article number: zcaa044. (10.1093/narcan/zcaa044)
• Ashworth, I. et al. 2021. Telomere length in Cystic Fibrosis patients - are patients with CF ageing too quickly?. International Journal of Aging Research 4, article number: 90. (10.28933/ijoar-2021-06-2005)

2019

• Cleal, K., Jones, R. E., Grimstead, J. W., Hendrickson, E. A. and Baird, D. M. 2019. Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin. Genome Research 29(5), pp. 737-749. (10.1101/gr.240705.118)

2018

• Ngo, G., Hyatt, S., Grimstead, J., Jones, R., Hendrickson, E., Pepper, C. and Baird, D. 2018. PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation. Oncotarget 9(101), pp. 37549-37563. (10.18632/oncotarget.26499)
• Garcia-Martin, I., Penketh, R., Janssen, A. B., Jones, R. E., Grimstead, J., Baird, D. and John, R. 2018. Meformin and insulin treatment prevent placental telomere attrition in boys exposed to maternal diabetes. PLoS ONE 13(12), article number: : e0208533. (10.1371/journal.pone.0208533)
• Harvey, A. et al. 2018. PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ. Oncotarget 9(78), pp. 34821-34837. (10.18632/oncotarget.26201)

2017

• Garcia Martin, I., Janssen, A., Jones, R., Grimstead, J. W., Penketh, R. J. A., Baird, D. M. and John, R. M. 2017. Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis. Placenta 59, pp. 61-68. (10.1016/j.placenta.2017.09.007)
• Williams, J. et al. 2017. Telomere length is an independent prognostic marker in MDS but not in de novo AML. British Journal of Haematology 178(2), pp. 240-249.
• Hyatt, S. et al. 2017. Telomere length is a critical determinant for survival in multiple myeloma. British Journal of Haematology 178(1), pp. 94-98. (10.1111/bjh.14643)
• Robinson, R., Grimstead, J., Sedani, A., Baird, D. and Upadhyaya, M. 2017. Telomere erosion in NF1 tumorigenesis. Oncotarget 8(25), pp. 40132-40139. (10.18632/oncotarget.16981)
• Letsolo, B., Robinson, R., Rowson, J., Grimstead, J., Keith, N., Jenkins, G. and Baird, D. M. 2017. Extensive telomere erosion is consistent with localised clonal expansions in Barrett's metaplasia. Plos One 12(3), article number: e0174833.

2015

• Simpson, K., Jones, R. E., Grimstead, J. W., Hills, R. K., Pepper, C. J. and Baird, D. M. 2015. Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients. Molecular Oncology 9(6), pp. 1186-1193. (10.1016/j.molonc.2015.02.003)

2014

• Lin, T. T. et al. 2014. Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease. British Journal of Haematology 167(2), pp. 214-223. (10.1111/bjh.13023)
• Jones, R. E. et al. 2014. Escape from telomere-driven crisis is DNA Ligase III dependent. Cell Reports 8(4), pp. 1063-1076. (10.1016/j.celrep.2014.07.007)

2013

• Davis, T., Tivey, H., Brook, A. J. C., Grimstead, J. W., Rokicki, M. J. and Kipling, D. G. 2013. Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome. AGE 35(5), pp. 1767-1783. (10.1007/s11357-012-9476-9)

2009

• McLaren, J. E., Zuo, J., Grimstead, J. W., Poghosyan, Z., Bell, A. I., Rowe, M. and Brennan, P. 2009. STAT1 contributes to the maintenance of the latency III viral programme observed in Epstein-Barr virus-transformed B cells and their recognition by CD8+ T cells. Journal of General Virology 90(9), pp. 2239-2250. (10.1099/vir.0.011627-0)