Dr Alan Scott
Postdoctoral Research Associate (with Prof Nigel Richards)
Biography
Publications
2021
- Scott, A. F., Deery, E., Lawrence, A. D. and Warren, M. J. 2021. Plasmodium falciparum hydroxymethylbilane synthase does not house any cosynthase activity within the haem biosynthetic pathway. Microbiology 167(10), article number: 1095. (10.1099/mic.0.001095)
- Mezoughi, A. B. et al. 2021. The lysozyme inhibitor thionine acetate is also an inhibitor of the soluble lytic transglycosylase Slt35 from escherichia coli. Molecules 26(14), article number: 4189. (10.3390/molecules26144189)
2019
- Allemann, R. K., Scott, A. F., Luk, L. Y., Tuñón, I. and Moliner, V. 2019. Heavy enzymes and the rational redesign of protein catalysts. ChemBioChem 20(22), pp. 2807-2812. (10.1002/cbic.201900134)
- Scott, A. F., Cresser-Brown, J., Williams, T. L., Rizkallah, P. J., Jin, Y., Luk, L. Y. and Allemann, R. K. 2019. Crystal structure and biophysical analysis of furfural detoxifying aldehyde reductase from clostridium beijerinkii. Applied and Environmental Microbiology (10.1128/AEM.00978-19)
2017
- Scott, A. F., Luk, L. Y. P. and Allemann, R. K. 2017. Chemical ligation and isotope labeling to locate dynamic effects. In: Imperiali, B. ed. Methods in Enzymology., Vol. 596. Elsevier, pp. 23-41., (10.1016/bs.mie.2017.06.040)
- Liddle, E., Scott, A., Han, L., Ivison, D., Simpson, T. J., Willis, C. L. and Cox, R. J. 2017. In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase. Chemical Communications 53(10), pp. 1727-1730. (10.1039/C6CC10172K)
2016
- Roberts, D. M., Bartel, C., Scott, A., Ivison, D., Simpson, T. J. and Cox, R. J. 2016. Substrate selectivity of an isolated enoyl reductase catalytic domain from an iterative highly reducing fungal polyketide synthase reveals key components of programming. Chemical Science 8(2), pp. 1116-1126. (10.1039/C6SC03496A)
2015
- Lobo, S. A. L. et al. 2015. Staphylococcus aureushaem biosynthesis: characterisation of the enzymes involved in final steps of the pathway. Molecular Microbiology 97(3), pp. 472-487. (10.1111/mmi.13041)
- Abood, A. et al. 2015. Kinetic characterisation of the FAD dependent monooxygenase TropB and investigation of its biotransformation potential. RSC Advances 5(62), pp. 49987-49995. (10.1039/C5RA06693J)
2014
- Lawrence, A. et al. 2014. FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR). Bioscience Reports 34(4), article number: e00120. (10.1042/BSR20140060)