Dr Jingjing Zhang
Research Fellow in Medical Statistics
- zhangj68@cardiff.ac.uk
- Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
Overview
Dr Jingjing Zhang obtained the B.Eng., M.Eng. and PhD degrees from Beijing Institute of Technology, Tsinghua University and Queen’s University Belfast, respectively. After graduated from Queen’s, she held several research posts in University of Dundee, Swansea University and Cardiff University.
Dr Zhang’s primary research interests cover statistics, data analytics, machine learning, causal inference and high-dimensional mediation data analysis with applications especially in the area of medical and public medicine. She has therefore been involved in several multi-disciplinary research projects including automated analysis of 3D OPT images of colorectal cancer, EEG based early detection and treatment of traumatic brain injury, immune fingerprints determination in acute infection, and statistics in population psychiatry, suicide and informatics.
Currently, Dr Zhang is a Research Fellow in Medical Statistics (funded by the Wellcome Trust) with the School of Medicine at Cardiff University. This research is focused on the development of statistical methods for exploring the complex causal pathways from genetic variants to cardiovascular disease via high-dimensional blood biomarkers such as proteins and metabolites.
Publications
2024
- Lalaurie, C., Zhang, C., Liu, S., Bunting, K. and Dalby, P. 2024. An open source in silico workflow to assist in the design of fusion proteins. Computational Biology and Chemistry 113, article number: 108209. (10.1016/j.compbiolchem.2024.108209)
2021
- Daniel, R., Zhang, J. and Farewell, D. 2021. Making apples from oranges: Comparing noncollapsible effect estimators and their standard errors after adjustment for different covariate sets. Biometrical Journal 63(3), pp. 528-557. (10.1002/bimj.201900297)
2019
- Gadalla, A. A. M. et al. 2019. Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms. Scientific Reports 9(1), article number: 19694. (10.1038/s41598-019-55523-x)
2017
- Zhang, J. et al. 2017. Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections. Kidney International 92(1), pp. 179-191. (10.1016/j.kint.2017.01.017)
2016
- Liuzzi, A. R. et al. 2016. Unconventional human T cells accumulate at the site of infection in response to microbial ligands and induce local tissue remodeling. Journal of Immunology 197(6), pp. 2195-2207. (10.4049/jimmunol.1600990)
2015
- Zhao, W., Zhang, J. and Li, K. 2015. An efficient LS-SVM based method for fuzzy system construction. IEEE Transactions on Fuzzy Systems 23(3), pp. 627-643. (10.1109/TFUZZ.2014.2321594)
- Zhang, J., Zhang, J., Coats, M., Li, W., Carey, F. and McKenna, S. 2015. Multi-scale analysis of the surface morphology of colorectal polyps from optical tomography. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization 5(5), pp. 318-328. (10.1080/21681163.2015.1035404)
2014
- Zhang, J., McKenna, S., Zhang, J., Coats, M. and Carey, F. A. 2014. Analysing the surface morphology of colorectal polyps: differential geometry and pit pattern prediction. Presented at: 18th Annual Conference in Medical Image Understanding and Analysis, London, United Kingdom.
- Zhang, J., Li, K., Zhao, W., Fei, M. and Wang, Y. 2014. A systematic fire detection approach based on sparse least-squares SVMs. Presented at: International Conference on Intelligent Computing for Sustainable Energy and Environment and International Conference on Life System Modeling and Simulation, Shanghai, China, 20 -23 September 2014 Presented at Fei, M. et al. eds.Computational Intelligence, Networked Systems and Their Applications, Vol. 462. Communications in Computer and Information Science Vol. 462. Berlin: Springer pp. 351-362., (10.1007/978-3-662-45261-5_37)
2012
- Zhang, J. and Li, K. 2012. Heuristic based model selection for a new least-squares SVM solution. Presented at: 26th European Simulation and Modelling Conference-ESM'2012, Essen, Germany, 22-24 October 2012.
- Zhang, J., Li, K., Irwin, G. W. and Zhao, W. 2012. A regression approach to LS-SVM and sparse realization based on fast subset selection. Presented at: 10th World Congress on Intelligent Control and Automation (WCICA), Beijing, China, 6-8 July 2012 Presented at Cheng, D. ed.Proceedings of the 10th World Congress on Intelligent Control and Automation July 6-8, 2012, Beijing, China. Piscataway, NJ: Institute of Electrical and Electronics Engineers pp. 612-617., (10.1109/WCICA.2012.6357952)
2011
- Zhang, J., Niu, Q., Li, K. and Irwin, G. W. 2011. Model selection in SVMs using differential evolution. IFAC Proceedings Volumes 44(1), pp. 14717-14722. (10.3182/20110828-6-IT-1002.00584)
Articles
- J. Zhang, I. M. Friberg et al., “Machine-learning Algorithms Define Pathogen-specific Local Immune Fingerprints in Peritoneal Dialysis Patients with Bacterial Infections," Kidney International, vol.92, no.1, pp.179-191, July 2017, DOI:http://10.1016/j.kint.2017.01.017.
- Liuzzi, A. Kift-Morgan, M. Lopez-Anton, I. M. Friberg, J. Zhang, A. C. Brook, G. W. Roberts et al., “Unconventional Human T Cells Accumulate at the Site of Infection in Response to Microbial Ligands and Induce Local Tissue Remodeling," The Journal of Immunology, vol.197, no.6, pp.2195-2207, September 2016, DOI:10.4049/jimmunol.1600990.
- W. Zhao, J. Zhang, K. Li, “A Novel Efficient LS-SVM Based Method for Fuzzy System Construction," IEEE Transactions on Fuzzy Systems, vol.23, no.3, pp.627-643, June 2015, DOI: 10.1109/TFUZZ.2014.2321594.
- J. Zhang, J. G. Zhang, W. Li, M. Coat, F. A. Carey and S. J. McKenna, “Multi-scale Analysis of the Surface Morphology of Colorectal Polyps from Optical Tomography," Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, vol.5, no.5, pp.318-328, 2017, DOI: 10.1080/21681163.2015.1035404.
Conference
- B. Albert, J.Zhang, A. Noyvirt, R. Setchi, H. Sjaaheim, S. Velikova and F. Strisland, “Automatic EEG Processing for the Early Diagnosis of Traumatic Brain Injury," In World Automation Congress (WAC), 2016 2016 Jul 31 (pp. 1-6). IEEE.
- J. Zhang, S. J. McKenna, J. G. Zhang, M. Coats and F. A. Carey, “Analysis the Surface Morphology of Colorectal Polyps: Differential Geometry and Pit Pattern Prediction," Proceeding of 18th Conference on Medical Image Understanding and Analysis (MIUA), London, 9-11 July 2014, pp.67-72, ISBN: 1901725510. (Award: British Association for Cancer Research Award for Best Cancer-related Paper)
- J. Zhang, K. Li, W. Q. Zhao, M. Fei and Y. Wang, “A Systematic Fire Detection Approach Based on Sparse Least-Squares SVMs," Communications in Computer and Information Science, vol. 462, pp. 351-362, Springer Berlin Heidelberg, 2014, DOI: 10.1007/978-3-662-45261-5 37.
- J. Zhang and K. Li, “Heuristic based Model Selection for a New Least-squares SVM solution," 26th European Simulation and Modelling Conference-ESM'2012, Essen, Germany, October 22-24, 2012.
- J. Zhang, K. Li, W. Q. Zhao and G. W. Irwin, “A Regression Approach to LS-SVM and Sparse Realization based on Fast Subset Selection," Proceeding of the 10th IEEE Word Congress on Intelligent Control and Automation (WCICA), Beijing, 6-8 July 2012, pp.612-617, DOI: 10.1109/WCICA.2012.6357952.
- J. Zhang, Q. Niu, K. Li and G. W. Irwin, “Model Selection in SVMs using Differential Evolution," Proceeding of 18th International Federation of Automatic Control World Congress (IFAC), Milan,Italy, Aug 28-2 Sept 2011, pp.14717-14722, DOI: 10.3182/20110828-6-IT-1002.00584.
Other
- Talk in Infection & Immunity Annual Meeting of Cardiff University 2015 with title of “Machine Learning and supercomputing approaches to define and cross-validate pathogen-specific local immune fingerprints in peritoneal dialysis patients presenting with acute peritonitis”
- Poster in Infection & Immunity Annual Meeting of Cardiff University 2016 with title of “Understanding immune response by applying machine learning methods”