Professor Aled Phillips

2021

• Woods, E. L. et al. 2021. CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1. Journal of Biological Chemistry 297(3), article number: 100987. (10.1016/j.jbc.2021.100987)
• Holmes, J., Donovan, K., Geen, J., Williams, J. and Phillips, A. O. 2021. Acute kidney injury demographics and outcomes: changes following introduction of electronic acute kidney injury alerts—an analysis of a national dataset. Nephrology Dialysis Transplantation 36(8), pp. 1433-1439. (10.1093/ndt/gfaa071)
• Khalid, S. A. et al. 2021. Gum Arabic in renal disease (GARDS Study): Clinical evidence of dietary supplementation impact on progression of renal dysfunction. Journal of Functional Foods 82, article number: 104515. (10.1016/j.jff.2021.104515)
• Jones, A., Holmes, J., Stephens, M., Geen, J., Williams, J., Donovan, K. and Phillips, A. O. 2021. Using electronic AKI alerts to define the epidemiology of acute kidney injury in renal transplants. Journal of Nephrology 34, pp. 829-838. (10.1007/s40620-020-00869-z)

2020

• Holmes, J., Geen, J., Williams, J. D. and Phillips, A. O. 2020. Recurrent acute kidney injury: predictors and impact in a large population-based cohort. Nephrology Dialysis Transplantation 35(8), pp. 1361-1369. (10.1093/ndt/gfz155)
• Midgley, A. C. et al. 2020. Hyaluronidase-2 regulates RhoA signalling, myofibroblast contractility and other key pro-fibrotic myofibroblast functions. American Journal of Pathology 190(6), pp. 1236-1255. (10.1016/j.ajpath.2020.02.012)
• Foxwell, D. A., Pradhan, S., Zouwail, S., Rainer, T. H. and Phillips, A. O. 2020. Epidemiology of emergency department acute kidney injury. Nephrology 25(6), pp. 457-466. (10.1111/nep.13672)
• Gubb, S., Holmes, J., Smith, G., Geen, J., Williams, J., Donovan, K. and Phillips, A. O. 2020. Acute kidney injury in children based on electronic alerts. Journal of Pediatrics 220, pp. 4-6.e1. (10.1016/j.jpeds.2019.11.019)

2019

• Allen, L. A., Pyart, R. D., Holmes, J., Donovan, K. L., Anderson, R. A. and Phillips, A. O. 2019. Cardiovascular and renal outcomes following percutaneous coronary intervention in a population with renal disease: a case-control study. QJM: An International Journal of Medicine 112(9), pp. 669-674. (10.1093/qjmed/hcz130)

2018

• Phillips, D., Holmes, J., Davies, R., Geen, J., Williams, J. D. and Phillips, A. O. 2018. The influence of socioeconomic status on presentation and outcome of acute kidney injury. QJM: An International Journal of Medicine 111(12), pp. 849-857. (10.1093/qjmed/hcy180)
• Wang, J. et al. 2018. Structural characterization of an α-1, 6-linked galactomannan from natural Cordyceps 2 sinensis. Food Hydrocolloids 78, pp. 77-91. (10.1016/j.foodhyd.2017.07.024)
• Huang, D. et al. 2018. Cordyceps Sinensis: anti-fibrotic and inflammatory effects of a cultured polysaccharide extract. Bioactive Carbohydrates and Dietary Fibre 14, pp. 2-8. (10.1016/j.bcdf.2017.07.012)

2017

• Midgley, A. C., Oltean, S., Hascall, V., Woods, E. L., Steadman, R., Phillips, A. O. and Meran, S. 2017. Nuclear hyaluronidase 2 drives alternative splicing of CD44 pre-mRNA to determine profibrotic or antifibrotic cell phenotype. Science Signaling 10(506), article number: eaao1822. (10.1126/scisignal.aao1822)
• Holmes, J., Geen, J., Phillips, B., Williams, J. and Phillips, A. 2017. Community acquired acute kidney injury: findings from a large population cohort. QJM: An International Journal of Medicine 110(11), pp. 741-746. (10.1093/qjmed/hcx151)
• Phillips, D. et al. 2017. Seasonal pattern of incidence and outcome of acute kidney injury: A national study of Welsh AKI electronic alerts. International Journal of Clinical Practice 71(9), article number: e13000. (10.1111/ijcp.13000)
• Holmes, J., Allen, N., Roberts, G., Geen, J., Williams, J. D. and Phillips, A. O. 2017. Acute kidney injury: electronic alerts in primary care - findings from a large population cohort. QJM: An International Journal of Medicine 110(9), pp. 577-582. (10.1093/qjmed/hcx080)
• Holmes, J., Roberts, G., May, K., Tyerman, K., Geen, J., Williams, J. D. and Phillips, A. O. 2017. The incidence of pediatric acute kidney injury is increased when identified by a change in a creatinine-based electronic alert. Kidney International 92(2), pp. 432-439. (10.1016/j.kint.2017.03.009)
• Wang, J. et al. 2017. Structural characterization and immunostimulatory activity of a glucan from natural Cordyceps sinensis. Food Hydrocolloids 67, pp. 139-147. (10.1016/j.foodhyd.2017.01.010)
• Wang, J. et al. 2017. Comparison of structural features and antioxidant activity of polysaccharides from natural and cultured Cordyceps sinensis. Food Science and Biotechnology 26(1), article number: 55. (10.1007/s10068-017-0008-3)

2016

• Holmes, J. et al. 2016. Acute kidney injury in the era of the AKI E-Alert. Clinical Journal of the American Society of Nephrology 11 (10.2215/CJN.05170516)
• Johnson, F., Phillips, D., Talabani, B., Wonnacott, A., Meran, S. and Phillips, A. 2016. The impact of acute kidney injury in diabetes mellitus. Journal of Thrombosis and Haemostatis 21(6), pp. 506-511. (10.1111/nep.12649)
• Midgley, A. C., Morris, G., Phillips, A. O. and Steadman, R. 2016. 17β‐estradiol ameliorates age‐associated loss of fibroblast function by attenuating IFN‐γ/STAT1‐dependent miR‐7 upregulation. Aging Cell 15(3), pp. 531-541. (10.1111/acel.12462)
• Martin, J., Midgley, A., Meran, S., Woods, E., Bowen, T., Phillips, A. O. and Steadman, R. 2016. Tumour necrosis factor-stimulated gene (TSG)-6-mediated interactions with the inter-alpha-inhibitor heavy chain 5 facilitate TGF beta1-dependent fibroblast to myofibroblast differentiation.. Journal of Biological Chemistry 291, pp. 13789-13801. (10.1074/jbc.M115.670521)
• El-hassan, E. E. A., Ghalib, M. B., Ibrahim, A. I. S., Phillips, B. and Phillips, A. 2016. Glomerular disease and acute kidney injury in Sudan: Demographics, histological diagnosis and outcome. South African Medical Journal 106(7), pp. 704-708. (10.7196/SAMJ.2016.v106i7.10392)

2015

• Beltrami, C. et al. 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1(2), pp. 151-166. (10.3390/ncrna1020151)
• Roberts, G. et al. 2015. Acute kidney injury risk assessment at the hospital front door: what is the best measure of risk?. Clinical Kidney Journal 8(6), pp. 673-680. (10.1093/ckj/sfv080)
• Midgley, A. C., Druggal, L., Jenkins, R., Hascall, V., Steadman, R., Phillips, A. O. and Meran, S. 2015. Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype. Journal of Biological Chemistry 290(18), pp. 11218-11234. (10.1074/jbc.M114.625939)

2014

• Wonnacott, A., Meran, S., Amphlett, B., Talabani, B. and Phillips, A. 2014. Epidemiology and outcomes in community-acquired versus hospital-acquired AKI. Clinical Journal of the American Society of Nephrology 9(6), pp. 1007-1014. (10.2215/CJN.07920713)
• Talabani, B., Zouwail, S., Pyart, R., Meran, S., Riley, S. and Phillips, A. 2014. Epidemiology and outcome of community-acquired acute kidney injury. Nephrology 19(5), pp. 282-287. (10.1111/nep.12221)
• Jenkins, R. H. et al. 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184(4), pp. 996-1009. (10.1016/j.ajpath.2013.12.028)
• Midgley, A. C., Bowen, T., Phillips, A. O. and Steadman, R. 2014. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell 13(2), pp. 235-244. (10.1111/acel.12167)
• Yao, X. et al. 2014. Cordyceps sinensis: in vitro anti-fibrotic bioactivity of natural and cultured preparations. Food Hydrocolloids 35, pp. 444-452. (10.1016/j.foodhyd.2013.06.023)
• Meran, S., Wonnacott, A., Amphlett, B. and Phillips, A. 2014. How good are we at managing acute kidney injury in hospital?. Clinical Kidney Journal 7(2), pp. 144-150. (10.1093/ckj/sfu010)
• Phillips, B. M., Milner, S., Zouwail, S., Roberts, G., Cowan, M., Riley, S. and Phillips, A. 2014. Severe hyperkalaemia: demographics and outcome. Clinical Kidney Journal 7(2), pp. 127-133. (10.1093/ckj/sft158)
• Phillips, L., Phillips, B., Meran, S., Russell, J., Zouwail, S., Riley, S. and Phillips, A. 2014. The long-term impact of eGFR reporting on referral patterns. European Journal of Internal Medicine 25(1), pp. 97-101. (10.1016/j.ejim.2013.08.001)

2013

• Jones, N. J., Chess, J. A., Cawley, S., Phillips, A. O. and Riley, S. G. 2013. Prevalence of risk factors for foot ulceration in a general haemodialysis population. International Wound Journal 10(6), pp. 683-688. (10.1111/j.1742-481X.2012.01044.x)
• Jones, R. K., Hampton, D., O'Sullivan, D. J. and Phillips, A. O. 2013. Diabetes and renal disease: who does what?. Clinical Medicine 13(5), pp. 460-464. (10.7861/clinmedicine.13-5-460)
• Pan, M., Zhang, M., Ni, H., Chen, J., Xu, M., Phillips, A. O. and Liu, B. 2013. Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats. Food and Chemical Toxicology 58, pp. 487-494. (10.1016/j.fct.2013.04.037)
• Meran, S., Martin, J., Luo, D. D., Steadman, R. and Phillips, A. O. 2013. Interleukin-1β induces hyaluronan and CD44-dependent cell protrusions that facilitate fibroblast-monocyte binding. American Journal of Pathology 182(6), pp. 2223-2240. (10.1016/j.ajpath.2013.02.038)
• Midgley, A. C., Rogers, M. J., Hallett, M. B., Clayton, A., Bowen, T., Phillips, A. O. and Steadman, R. 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288(21), pp. 14824-14838. (10.1074/jbc.M113.451336)
• Phillips, L. A. et al. 2013. Acute kidney injury risk factor recognition in three teaching hospitals in Ethiopia. South African Medical Journal 103(6), pp. 413-418. (10.7196/samj.6424)
• Nie, S., Cui, S. W., Xie, M., Phillips, A. O. and Phillips, G. O. 2013. Bioactive polysaccharides from Cordyceps sinensis: Isolation, structure features and bioactivities [Review]. Bioactive Carbohydrates and Dietary Fibre 1(1), pp. 38-52. (10.1016/j.bcdf.2012.12.002)
• Riley, S. G. et al. 2013. Renal impairment amongst acute hospital admissions in a rural Ethiopian hospital. Nephrology 18(2), pp. 92-96. (10.1111/nep.12002)

2012

• Wonnacott, A., Meran, S., Roberts, G. W., Donovan, K., Riley, S. G. and Phillips, A. O. 2012. Applying estimated glomerular filtration rate to an ageing population: are we in danger of becoming ageist?. European Journal of Internal Medicine 23(8), pp. 705-710. (10.1016/j.ejim.2012.08.012)
• Zhang, X. L., Bi-Cheng, L., Al-Assaf, S., Phillips, G. O. and Phillips, A. O. 2012. Cordyceps sinensis decreases TGF-β1 dependent epithelial to mesenchymal transdifferentiation and attenuates renal fibrosis. Food Hydrocolloids 28(1), pp. 200-212. (10.1016/j.foodhyd.2011.12.016)
• Jenkins, R. H., Martin, J., Phillips, A. O., Bowen, T. and Fraser, D. J. 2012. Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding. Biochemical Journal 443(2), pp. 407-416. (10.1042/BJ20111861)
• Jenkins, R. H., Martin, J., Phillips, A. O., Bowen, T. and Fraser, D. J. 2012. Pleiotropy of microRNA-192 in the kidney. Biochemical Society Transactions 40(4), pp. 762-767. (10.1042/BST20120085)
• Beltrami, C., Clayton, A., Phillips, A. O., Fraser, D. J. and Bowen, T. 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40(4), pp. 875-879. (10.1042/BST20120090)
• Zheng, M. et al. 2012. Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy. Clinical Endocrinology 76(5), pp. 657-664. (10.1111/j.1365-2265.2011.04192.x)

2011

• Bommayya, G., Meran, S., Krupa, A., Phillips, A. O. and Steadman, R. 2011. Tumour necrosis factor-stimulated gene (TSG)-6 controls epithelial–mesenchymal transition of proximal tubular epithelial cells. International Journal of Biochemistry & Cell Biology 43(12), pp. 1739-1746. (10.1016/j.biocel.2011.08.009)
• Michael, D. R. et al. 2011. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. Journal of Biological Chemistry 286(22), pp. 19523-19532. (10.1074/jbc.M111.233916)
• Li, Q., Liu, B., Lv, L., Ma, K., Zhang, X. and Phillips, A. O. 2011. Monocytes induce proximal tubular epithelial-mesenchymal transition through NF-kappa B dependent upregulation of ICAM-1. Journal of Cellular Biochemistry 112(6), pp. 1585-1592. (10.1002/jcb.23074)
• Meran, S., Luo, D. D., Simpson, R. M. L., Martin, J., Wells, A., Steadman, R. and Phillips, A. O. 2011. Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction. Journal of Biological Chemistry 286(20), pp. 17618-17630. (10.1074/jbc.M111.226563)
• Martin, J., Jenkins, R. H., Bennagi, R., Krupa, A., Phillips, A. O., Bowen, T. and Fraser, D. J. 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6(10), article number: e25044. (10.1371/journal.pone.0025044)
• Nie, S., Cui, S. W., Phillips, A. O., Xie, M., Phillips, G. O., Al-Assaf, S. and Zhang, X. 2011. Elucidation of the structure of a bioactive hydrophilic polysaccharide from Cordyceps sinensis by methylation analysis and NMR spectroscopy. Carbohydrate Polymers 84(3), pp. 894-899. (10.1016/j.carbpol.2010.12.033)
• Asderakis, A., Chaudhry, A., Ilham, M. A., Stephens, M. and Phillips, A. O. 2011. RO-101 Nitric oxide post-perfusion levels differ in DCD and DBD donor transplants [Abstract]. Transplant International 24(s2), pp. 157. (10.1111/j.1432-2277.2011.01350.x)
• Tian, Y. et al. 2011. Leptospira santorosai serovar shermani detergent extract induces an increase in fibronectin production through a toll-like receptor 2-mediated pathway. Infection and Immunity 79(3), pp. 1134-1142. (10.1128/IAI.01287-09)
• Phillips, A. O. and Phillips, G. O. 2011. Biofunctional behaviour and health benefits of a specific gum arabic. Food Hydrocolloids 25(2), pp. 165-169. (10.1016/j.foodhyd.2010.03.012)
• Khammas, H., Bowen, T., Williams, J. D., Phillips, A. O., Steadman, R. and Martin, J. 2011. Characterisation of the human ADAM15 promoter. Nephron Experimental Nephrology 118(2), pp. e27-e38. (10.1159/000320698)

2010

• Jenkins, R. H., Bennagi, R., Martin, J., Phillips, A. O., Redman, J. E. and Fraser, D. J. 2010. A conserved stem loop motif in the 5'Untranslated Region regulates transforming growth factor-β1 translation. PLoS One 5(8), article number: e12283. (10.1371/journal.pone.0012283)
• Simpson, R. M. L., Wells, A., Thomas, D. W., Stephens, P., Steadman, R. and Phillips, A. O. 2010. Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling. American Journal of Pathology 176(3), pp. 1215-1228. (10.2353/ajpath.2010.090802)
• Krupa, A., Jenkins, R. H., Luo, D. D., Lewis, A. G., Phillips, A. O. and Fraser, D. J. 2010. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. Journal of the American Society of Nephrology 21(3), pp. 438-447. (10.1681/ASN.2009050530)
• Luo, D. D., Phillips, A. O. and Fraser, D. J. 2010. Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell smad3 signaling via increased SnoN expression. American Journal of Pathology 176(3), pp. 1139-1147. (10.2353/ajpath.2010.090459)
• Meran, S., Don, K., Shah, N., Donovan, K., Riley, S. G. and Phillips, A. O. 2010. Impact of chronic kidney disease management in primary care. QJM 104(1), pp. 27-34. (10.1093/qjmed/hcq151)
• Phillips, A. O. and Fraser, D. J. 2010. BMP-7 stops TGF-β in peritoneal fibrosis. Nephrology Dialysis Transplantation 25(4), pp. 1036-1038. (10.1093/ndt/gfq032)

2009

• Simpson, R. M. L., Meran, S., Thomas, D. W., Stephens, P., Bowen, T., Steadman, R. and Phillips, A. O. 2009. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. American Journal of Pathology 175(5), pp. 1915-1928. (10.2353/ajpath.2009.090045)
• Webber, J. P., Jenkins, R. H., Meran, S., Phillips, A. O. and Steadman, R. 2009. Modulation of TGFβ1-dependent myofibroblast differentiation by hyaluronan. American Journal of Pathology 175(1), pp. 148-160. (10.2353/ajpath.2009.080837)
• Webber, J. P., Meran, S., Steadman, R. and Phillips, A. O. 2009. Hyaluronan orchestrates transforming growth factor-β1-dependent maintenance of myofibroblast phenotype. Journal of Biological Chemistry 284(14), pp. 9083-9092. (10.1074/jbc.M806989200)
• Simpson, R. M., Stephens, P., Thomas, D., Webber, J. P., Meran, S., Steadman, R. and Phillips, A. O. 2009. Age related changes in pericellular hyaluronan leads to impaired dermal fibroblast to myofibroblast differentiation. International Journal of Experimental Pathology 90(2), pp. A128-A129.
• Luo, D. D., Fielding, C. A., Phillips, A. O. and Fraser, D. J. 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24(9), pp. 2655-2665. (10.1093/ndt/gfp208)
• Glover, D. A., Ushida, K., Phillips, A. O. and Riley, S. G. 2009. Acacia(sen) SUPERGUM™ (gum arabic): an evaluation of potential health benefits in human subjects. Food Hydrocolloids 23(8), pp. 2410-2415. (10.1016/j.foodhyd.2009.06.020)
• Phillips, L. A., Donovan, K. and Phillips, A. O. 2009. Renal quality outcomes framework and eGFR: impact on secondary care. QJM 102(6), pp. 415-423. (10.1093/qjmed/hcp030)

2008

• Meran, S., Thomas, D. W., Stephens, P., Enoch, S., Martin, J., Steadman, R. and Phillips, A. O. 2008. Hyaluronan facilitates transforming growth factor-β1-mediated fibroblast proliferation. Journal of Biological Chemistry 283(10), pp. 6530-6545. (10.1074/jbc.M704819200)
• Fraser, D. J., Phillips, A. O., Zhang, X. L., van Roeyen, C. R., Muehlenberg, P., En-Nia, A. and Mertens, P. R. 2008. Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells. Kidney International 73(6), pp. 724-732. (10.1038/sj.ki.5002719)
• Lewis, A. G., Steadman, R., Manley, P., Craig, K. J., de la Motte, C., Hascall, V. and Phillips, A. O. 2008. Diabetic nephropathy, inflammation, hyaluronan and interstitial fibrosis. Histology and Histopathology 23(6), pp. 731-739.
• Liu, B. C., Li, M. X., Zhang, J. D., Liu, X. C., Zhang, X. L. and Phillips, A. O. 2008. Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition. American Journal of Nephrology 28(1), pp. 143-151. (10.1159/000110019)
• Meran, S., Steadman, R., Phillips, A. O., Thomas, D. W. and Stephens, P. 2008. Hyaluronan facilitates TGF beta 1 mediated myofibroblastic differentiation [Abstract]. Wound Repair and Regeneration 16(2), pp. A12. (10.1111/j.1524-475X.2008.00371.x)
• Chang, C. et al. 2008. Transforming growth factor-β1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway. Nephrology Dialysis Transplantation 23(4), pp. 1126-1134. (10.1093/ndt/gfm786)
• Nair, S. et al. 2008. Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening. Journal of Nephology 21(3), pp. 400-405.

2007

• Zhang, M., Lee, C., Luo, D. D., Krupa, A., Fraser, D. J. and Phillips, A. O. 2007. Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin. Journal of Biological Chemistry 282(39), pp. 28639-28647. (10.1074/jbc.m700594200)
• Meran, S., Thomas, D. W., Stephens, P., Martin, J., Bowen, T., Phillips, A. O. and Steadman, R. 2007. Involvement of hyaluronan in regulation of fibroblast phenotype. The Journal of Biological Chemistry 282(35), pp. 25687-25697. (10.1074/jbc.M700773200)

2006

• Rashid Selbi, W., de la Motte, C. A., Hascall, V. C., Day, A. J., Bowen, T. and Phillips, A. O. 2006. Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. Kidney International 70(7), pp. 1287-1295. (10.1038/sj.ki.5001760)
• Zhang, M., Fraser, D. J. and Phillips, A. O. 2006. ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. American Journal of Pathology 169(4), pp. 1282-1293. (10.2353/ajpath.2006.050921)
• Khera, T., Martin, J., Riley, S. G., Steadman, R. and Phillips, A. O. 2006. Glucose enhances mesangial cell apoptosis. Laboratory Investigation 86(6), pp. 566-577. (10.1038/labinvest.3700418)
• Matsumoto, N. et al. 2006. Butyrate modulates TGF-beta1 generation and function: potential renal benefit for Acacia(sen) SUPERGUM (gum arabic)?. Kidney International 69(2), pp. 257-65. (10.1038/sj.ki.5000028)

2005

• Craig, K. J. et al. 2005. Anemia and diabetes in the absence of nephropathy. Diabetes Care 28(5), pp. 1118-1123. (10.2337/diacare.28.5.1118)
• Zhang, X. L., Topley, N., Ito, T. and Phillips, A. O. 2005. Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. The Journal of Biological Chemistry 280(13), pp. 12239-12245. (10.1074/jbc.M413284200)
• Zhang, X. L., Rashid Selbi, W. D., Motte, C. d. l., Hascall, V. and Phillips, A. O. 2005. Bone morphogenic protein-7 inhibits monocyte-stimulated TGF-beta1 generation in renal proximal tubular epithelial cells. Journal of the American Society of Nephrology 16(1), pp. 79-89. (10.1681/ASN.2004050395)
• Craig, K. L., Riley, S. G., Thomas, B., Penney, M., Donovan, K. and Phillips, A. O. 2005. The impact of an out-reach clinic on referral of patients with renal impairment. Nephron Clinical Practice 101(4), pp. c168-c173. (10.1159/000087392)

2004

• Zhang, X. L., Rashid Selbi, W. D., Motte, C. d. l., Hascall, V. and Phillips, A. O. 2004. Renal proximal tubular epithelial cell transforming growth factor-beta1 generation and monocyte binding. American Journal of Pathology 165(3), pp. 763-773.
• Ito, T., Williams, J. D., Fraser, D. J. and Phillips, A. O. 2004. Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalization. The Journal of Biological Chemistry 279(24), pp. 25326-25332. (10.1074/jbc.M403135200)
• Ito, T., Williams, J. D., Fraser, D. and Phillips, A. O. 2004. Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. American Journal of Pathology 164(6), pp. 1979-1988. (10.1016/s0002-9440(10)63758-3)

2003

• Fraser, D. J., Brunskill, N., Ito, T. and Phillips, A. O. 2003. Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop. American Journal of Pathology 163(6), pp. 2565-2574.
• Tian, Y., Fraser, D. J., Attisano, L. and Phillips, A. O. 2003. TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype. American Journal of Physiology - Renal Physiology 285(1), pp. F130-142. (10.1152/ajprenal.00408.2002)
• Craig, K. J., Donovan, K., Munnery, M., Owens, D. R., Williams, J. D. and Phillips, A. O. 2003. Identification and management of diabetic nephropathy in the diabetes clinic. Diabetes Care 26(6), pp. 1806-1811. (10.2337/diacare.26.6.1806)
• Wong, T. Y. H., Phillips, A. O., Witowski, J. and Topley, N. 2003. Glucose-mediated induction of TGF-beta 1 and MCP-1 in mesothelial cells in vitro is osmolality and polyol pathway dependent. Kidney International 63(4), pp. 1404-1416. (10.1046/j.1523-1755.2003.00883.x)

2002

• Fraser, D. J., Phillips, A. O. and Wakefield, L. 2002. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. American Journal of Pathology 161(3), pp. 1039-1049.