Dr Joachim Bugert
Senior Lecturer, School of Medicine
- bugertjj@cardiff.ac.uk
- +44 29207 43583/42172
- UHW Main Building
- Media commentator
Biography
Publications
2020
- Elasifer, H. et al. 2020. Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion. Journal of General Virology 101, pp. 863-872. (10.1099/jgv.0.001417)
2017
- Houston, D. M. J., Bugert, J. J., Denyer, S. P. and Heard, C. M. 2017. Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV. PLoS ONE 12(6), article number: e0179291. (10.1371/journal.pone.0179291)
- Houston, D., Bugert, J., Denyer, S. P. and Heard, C. M. 2017. Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin. European Journal of Pharmaceutics and Biopharmaceutics 112, pp. 30-37. (10.1016/j.ejpb.2016.11.014)
2016
- McGuigan, C. et al. 2016. Anti-flavivirus activity of different tritylated pyrimidine and purine nucleoside analogues. ChemistryOpen 5(3), pp. 227-235. (10.1002/open.201500216)
2015
- Toleman, M. A., Bugert, J. J. and Nizam, S. A. 2015. Extensively drug-resistant New Delhi metallo-β-lactamase–encoding bacteria in the environment, Dhaka, Bangladesh, 2012. Emerging Infectious Disease 21(6), pp. 1027-1030. (10.3201/eid2106.141578)
- Bugert, J. J. and Kruger, D. H. 2015. From the editors. Virus Genes 50(1), pp. 1. (10.1007/s11262-015-1176-y)
2013
- Ford, W. R., Blair, A. E., Evans, R. L., John, E., Bugert, J. J., Broadley, K. J. and Kidd, E. J. 2013. Human parainfluenza type 3 virus impairs the efficacy of glucocorticoids to limit allergy-induced pulmonary inflammation in guinea-pigs. Clinical Science 125(10), pp. 471-482. (10.1042/CS20130130)
- Chen, X., Anstey, A. V. and Bugert, J. J. 2013. Molluscum contagiosum virus infection [review]. The Lancet Infectious Diseases 13(10), pp. 877-888. (10.1016/S1473-3099(13)70109-9)
- McGuigan, C., Hinsinger, K., Farleigh, L., Pathirana, R. and Bugert, J. J. 2013. Novel antiviral activity of l-dideoxy bicyclic nucleoside analogues versus vaccinia and measles viruses in vitro. Journal of Medicinal Chemistry 56(3), pp. 1311-1322. (10.1021/jm301778x)
2010
- Broadley, K. J., Blair, A. E., Kidd, E. J., Bugert, J. J. and Ford, W. R. 2010. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity. Journal of Pharmacology and Experimental Therapeutics 335(3), pp. 681-692. (10.1124/jpet.110.171876)
- Ingram, G., Bugert, J. J., Loveless, S. and Robertson, N. 2010. Anti-EBNA-1 IgG is not a reliable marker of multiple sclerosis clinical disease activity. European Journal of Neurology 17(11), pp. 1386-1389. (10.1111/j.1468-1331.2010.03083.x)
2009
- Bugert, J. J. 2009. Medizinisch relevante Pockenviren von Mensch und Tier. In: Neumeister, B. et al. eds. Mikrobiologische Diagnostik. 2nd ed.. Stuttgart: Thieme Verlag, pp. 730-739.
2008
- McGuigan, C., Derudas, M., Bugert, J. J., Andrei, G., Snoeck, R. and Balzarini, J. 2008. Successful kinase bypass with new acyclovir phosphoramidate prodrugs. Biorganic and Medicinal Chemistry Letters 18(15), pp. 4364-4367. (10.1016/j.bmcl.2008.06.069)
- Derudas, M., McGuigan, C., Brancale, A., Bugert, J. J., Andrei, G., Snoeck, R. and Balzarini, J. 2008. Design, synthesis and biological evaluation of novel acyclovir ProTides. Antiviral Research 78(2), pp. A55-A56., article number: 102. (10.1016/j.antiviral.2008.01.116)
- Bugert, J. J. 2008. Molluscum contagiosum virus. In: Mahy, B. W. J. and Van Regenmortel, M. H. V. eds. Encyclopedia of Virology 3rd ed. Amsterdam: Elsevier, pp. 319-324., (10.1016/B978-012374410-4.00444-1)
2007
- Ernst, E., Schönig, K., Bugert, J. J., Bläker, H., Pfaff, E., Stremmel, W. and Encke, J. 2007. Generation of inducible hepatitis C virus transgenic mouse lines. Journal of Medical Virology 79(8), pp. 1103-1112. (10.1002/jmv.20911)
- Bugert, J. J. 2007. Genus molluscipoxvirus. In: Mercer, A., Schmidt, A. and Weber, O. eds. Poxviruses. Advances in Infectious Diseases Basel: Birkhäuser, pp. 89-112., (10.1007/978-3-7643-7557-7)
2006
- Eisenbach, C. et al. 2006. Multigenotype HCV-NS3 recombinant vaccinia viruses as a model for evaluation of cross-genotype immunity induced by HCV vaccines in the mouse. Vaccine 24(24), pp. 5140-5148. (10.1016/j.vaccine.2006.04.013)
2005
- Bugert, J. J. 2005. Clinical virologists and the smallpox-threat: a comparison between Germany and the UK. In: Berencsi, G., Khan, A. B. and Haloužka, J. eds. Emerging Biological Threat. NATO Science Series, I: Life and Behavioural Sciences Vol. 370. Amsterdam: IOS Press, pp. 146.
2004
- Melquiot, N. V. and Bugert, J. J. 2004. Preparation and use of molluscum contagiosum virus from human tissue biopsy specimens. In: Isaacs, S. N. ed. Vaccinia Virus and Poxvirology: Methods and Protocols. Methods in Molecular Biology Vol. 269. Totowa, NJ.: Humana Press, pp. 371-383., (10.1385/1-59259-789-0:371)
2001
- Bugert, J. J., Melquiot, N. and Kehm, R. 2001. Molluscum contagiosum virus expresses late genes in primary human fibroblasts but does not produce infectious progeny. Virus Genes 22(1), pp. 27-33. (10.1023/A:1008126217725)
- Bugert, J. J. and Melquiot, N. V. 2001. Molluscipoxvirus. In: Tidona, C. and Darai, G. eds. The Springer Index of Viruses. Springer, pp. 1479-1484., (10.1007/978-0-387-95919-1_242)
2000
- Bugert, J. J., Melquiot, N. V. and Darai, G. 2000. Mapping of mRNA transcripts in the genome of molluscum contagiosum virus: transcriptional analysis of the viral slam gene family. Virus Genes 21(3), pp. 189-192. (10.1023/A:1008187430053)
- Bugert, J. J. and Darai, G. 2000. Poxvirus homologues of cellular genes. Virus Genes 21(1-2), pp. 111-133. (10.1023/A:1008140615106)
- Springfield, C., Bugert, J. J., Schnitzler, P., Tobiasch, E., Kehm, R. and Darai, G. 2000. TT virus as a human pathogen: Significance and problems. Virus Genes 20(1), pp. 35-45. (10.1023/A:1008156022845)
1999
- Bugert, J. J., Lohmüller, C. and Darai, G. 1999. Characterization of early gene transcripts of molluscum contagiosum virus. Virology 257(1), pp. 119-129. (10.1006/viro.1999.9649)
- Bugert, J. J., Welzel, T. M., Zeier, M. and Darai, G. 1999. Hantavirus infection-haemorrhagic fever in the Balkans-potential nephrological hazards in the Kosovo war. Nephrology Dialysis Transplantation 14(8), pp. 1843-1844. (10.1093/ndt/14.8.1843)
1998
- Bugert, J. J., Lohmüller, C., Damon, I., Moss, B. and Darai, G. 1998. Chemokine homolog of molluscum contagiosum virus: Sequence conservation and expression. Virology 242(1), pp. 51-59. (10.1006/viro.1997.9001)
1997
- Senkevich, T. G., Koonin, E. V., Bugert, J. J., Darai, G. and Moss, B. 1997. The genome of molluscum contagiosum virus: Analysis and comparison with other poxviruses. Virology 233(1), pp. 19-42. (10.1006/viro.1997.8607)
- Bugert, J. J. and Darai, G. 1997. Recent advances in molluscum contagiosum virus research. In: Kaaden, O., Czerny, C. and Eichhorn, W. eds. Viral zoonoses and food of animal origin : a re-evaluation of possible hazards for human health. New York, NY: Springer, pp. 35-47., (10.1007/978-3-7091-6534-8_4)
1996
- Senkevich, T. G., Bugert, J. J., Sisler, J. R., Koonin, E. V., Darai, G. and Moss, B. 1996. Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes. Science 273(5276), pp. 813-816. (10.1126/science.273.5276.813)
1995
- Sonntag, K., Clauer, U., Bugert, J. J., Schnitzler, P. and Darai, G. 1995. Identification and properties of the genes encoding the poly(A) polymerase and a small (22 kDa) and the largest subunit (147 kDa) of the DNA-Dependent RNA polymerase of molluscum contagiosum virus. Virology 210(2), pp. 471-478. (10.1006/viro.1995.1364)
1994
- Rode, H. et al. 1994. Molecular characterization and determination of the coding capacity of the genome of equine herpesvirus type 2 between the genome coordinates 0.235 and 0.258 (theEcoRI DNA fragment N; 4.2 kbp). Virus Genes 9(1), pp. 61-75. (10.1007/BF01703436)
- Schnitzler, P., Sonntag, K., Muller, M., Janssen, W., Bugert, J. J., Koonin, E. V. and Darai, G. 1994. Insect iridescent virus type 6 encodes a polypeptide related to the largest subunit of eukaryotic RNA polymerase II. Journal of General Virology 75(7), pp. 1557-1567. (10.1099/0022-1317-75-7-1557)
1993
- Rode, H., Janssen, W., Rösen-Wolff, A., Bugert, J. J., Thein, P., Becker, Y. and Darai, G. 1993. The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene. Virus Genes 7(1), pp. 111-116. (10.1007/BF01702353)
- Bugert, J. J., Raab, K., Rösen-Wolff, A., Janssen, W. and Darai, G. 1993. Determination of the position of the boundaries of the terminal repetitive sequences within the genome of molluscum contagiosum virus type 1 by DNA nucleotide sequence analysis. Virology 192(1), pp. 391-396. (10.1006/viro.1993.1050)
- Hadasch, R. P., Bugert, J. J., Janssen, W. and Darai, G. 1993. Characterization of the genome of molluscum contagiosum virus type 1 between the genome coordinates 0.045 and 0.075 by DNA nucleotide sequence analysis of a 5.6-kb HindIII/MluI DNA fragment. Intervirology 36(1), pp. 32-43. (10.1159/000150319)
1991
- Bugert, J. J. and Darai, G. 1991. Stability of molluscum contagiosum virus DNA among 184 patient isolates: Evidence for variability of sequences in the terminal inverted repeats. Journal of Medical Virology 33(3), pp. 211-217. (10.1002/jmv.1890330313)
1989
- Bugert, J. J., Rösen-Wolff, A. and Darai, G. 1989. Genomic characterization of molluscum contagiosum virus type 1: Identification of the repetitive DNA sequences in the viral genome. Virus Genes 3(2), pp. 159-173. (10.1007/BF00125128)
- Scholz, J., Rösen-Wolff, A., Bugert, J. J., Reisner, H., White, M. I., Darai, G. and Postlethwaite, R. 1989. Epidemiology of molluscum contagiosum using genetic analysis of the viral DNA. Journal of Medical Virology 27(2), pp. 87-90. (10.1002/jmv.1890270203)
1988
- Scholz, J., Bugert, J. J., Fischer, M., Rosen-Wolff, A. and Darai, G. 1988. Molecular epidemiology of mollescum contagiosum virus [Abstract]. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology 269(1), pp. 117. (10.1016/S0176-6724(88)80119-6)
- Scholz, J., Wolff, A. R., Bugert, J. J., Reisner, H., White, M. I., Darai, G. and Postlethwaite, R. 1988. Molecular Epidemiology of Molluscum Contagiosum. International Journal of Infectious Diseases 158(4), pp. 898-900. (10.1093/infdis/158.4.898)
1987
- Scholz, J., Reisner, H., Bugert, J. J. and Darai, G. 1987. Molecular characterization of the genome of mollescum contagiosum virus [Abstract]. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology 267(1), pp. 146. (10.1016/S0176-6724(87)80192-X)