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Mr Michael Cousins
Research Thesis Respiratory health outcomes in neonates - A double blinded randomised control trial investigating mechanisms and treatments of lung disease in preterm born children
Publications 2024 Course, C. W. et al. 2024. Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease . Scientific Reports 14(1), article number: 23294. (10.1038/s41598-024-73704-1 ) Watkins, W. J., Course, C. W., Cousins, M., Hart, K., Kotecha, S. J. and Kotecha, S. 2024. Impact of ambient air pollution on lung function in preterm-born school-aged children . Thorax 79(6), pp. 553-563. (10.1136/thorax-2023-220233 ) 2023 Cousins, M., Hart, K., Radics, B. L., Henderson, A. J., Hantos, Z., Sly, P. D. and Kotecha, S. 2023. Peripheral airway dysfunction in prematurity‐associated obstructive lung disease identified by oscillometry . Pediatric Pulmonology 58(11), pp. 3279-3292. (10.1002/ppul.26658 ) Course, C. W. et al. 2023. Evidence of abnormality in glutathione metabolism in the airways of preterm born children with a history of bronchopulmonary dysplasia . Scientific Reports 13(1), article number: 19465. (10.1038/s41598-023-46499-w ) Kotecha, E. et al. 2023. Association of early and current life factors with telomere length in preterm-born children . PLoS ONE 18(11), article number: e0293589. (10.1371/journal.pone.0293589 ) Cousins, M., Hart, K., Kotecha, S. J., Henderson, A. J., Watkins, W. J., Bush, A. and Kotecha, S. 2023. Characterising airway obstructive, dysanaptic and PRISm phenotypes of prematurity-associated lung disease . Thorax 78(9), pp. 895-903. (10.1136/thorax-2022-219301 ) Course, C. W. et al. 2023. Modulation of pulmonary desmosomes by inhaler therapy in preterm-born children with bronchopulmonary dysplasia . Scientific Reports 13, article number: 7330. (10.1038/s41598-023-34233-5 ) Course, C. W., Kotecha, S. J., Cousins, M., Hart, K., Lowe, J., Watkins, W. J. and Kotecha, S. 2023. Association of gestation and fetal growth restriction on cardiovascular health in preterm-born children . Journal of Pediatrics 255, pp. 42-49. (10.1016/j.jpeds.2022.09.057 ) Chan, H. et al. 2023. Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout . American Journal of Respiratory and Critical Care Medicine 207(1), pp. 89-90. (10.1164/rccm.202203-0606OC ) 2022 Cousins, M., Hart, K., Williams, E. M. and Kotecha, S. 2022. Impaired exercise outcomes with significant bronchodilator responsiveness in children with prematurity-associated obstructive lung disease . Pediatric Pulmonology 57(9), pp. 2161-2171. (10.1002/ppul.26019 ) Kotecha, S., Cousins, M., Hart, K., Watkins, W. J. and Kotecha, S. 2022. Effect of IUGR and catch-up growth on later lung function in preterm children: prospective cohort study . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1186., (10.1183/13993003.congress-2022.1186 ) Kotecha, S., Hart, K., Cousins, M., Watkins, W. J., Henderson, A. J. and Kotecha, S. 2022. Association of early life factors with prematurity-associated lung disease : prospective cohort study . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1183., (10.1183/13993003.congress-2022.1183 ) Kotecha, E. et al. 2022. Telomere length in preterm-born children with bronchopulmonary dysplasia (BPD) . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1292., (10.1183/13993003.congress-2022.1292 ) Hart, K., Cousins, M., Watkins, W. J., Kotecha, S. J., Henderson, A. J. and Kotecha, S. 2022. Association of early life factors with prematurity-associated lung disease: prospective cohort study . European Respiratory Journal 59(5), article number: 2101766. (10.1183/13993003.01766-2021 ) Goulden, N. et al. 2022. Inhaled corticosteroids alone and in combination with long-acting β2 receptor agonists to treat reduced lung function in preterm-born children: a randomized clinical trial . JAMA Pediatrics 176(2), pp. 133-141. (10.1001/jamapediatrics.2021.5111 ) 2021 2018 2017 Articles Course, C. W. et al. 2024. Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease . Scientific Reports 14(1), article number: 23294. (10.1038/s41598-024-73704-1 ) Watkins, W. J., Course, C. W., Cousins, M., Hart, K., Kotecha, S. J. and Kotecha, S. 2024. Impact of ambient air pollution on lung function in preterm-born school-aged children . Thorax 79(6), pp. 553-563. (10.1136/thorax-2023-220233 ) Cousins, M., Hart, K., Radics, B. L., Henderson, A. J., Hantos, Z., Sly, P. D. and Kotecha, S. 2023. Peripheral airway dysfunction in prematurity‐associated obstructive lung disease identified by oscillometry . Pediatric Pulmonology 58(11), pp. 3279-3292. (10.1002/ppul.26658 ) Course, C. W. et al. 2023. Evidence of abnormality in glutathione metabolism in the airways of preterm born children with a history of bronchopulmonary dysplasia . Scientific Reports 13(1), article number: 19465. (10.1038/s41598-023-46499-w ) Kotecha, E. et al. 2023. Association of early and current life factors with telomere length in preterm-born children . PLoS ONE 18(11), article number: e0293589. (10.1371/journal.pone.0293589 ) Cousins, M., Hart, K., Kotecha, S. J., Henderson, A. J., Watkins, W. J., Bush, A. and Kotecha, S. 2023. Characterising airway obstructive, dysanaptic and PRISm phenotypes of prematurity-associated lung disease . Thorax 78(9), pp. 895-903. (10.1136/thorax-2022-219301 ) Course, C. W. et al. 2023. Modulation of pulmonary desmosomes by inhaler therapy in preterm-born children with bronchopulmonary dysplasia . Scientific Reports 13, article number: 7330. (10.1038/s41598-023-34233-5 ) Course, C. W., Kotecha, S. J., Cousins, M., Hart, K., Lowe, J., Watkins, W. J. and Kotecha, S. 2023. Association of gestation and fetal growth restriction on cardiovascular health in preterm-born children . Journal of Pediatrics 255, pp. 42-49. (10.1016/j.jpeds.2022.09.057 ) Chan, H. et al. 2023. Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout . American Journal of Respiratory and Critical Care Medicine 207(1), pp. 89-90. (10.1164/rccm.202203-0606OC ) Cousins, M., Hart, K., Williams, E. M. and Kotecha, S. 2022. Impaired exercise outcomes with significant bronchodilator responsiveness in children with prematurity-associated obstructive lung disease . Pediatric Pulmonology 57(9), pp. 2161-2171. (10.1002/ppul.26019 ) Hart, K., Cousins, M., Watkins, W. J., Kotecha, S. J., Henderson, A. J. and Kotecha, S. 2022. Association of early life factors with prematurity-associated lung disease: prospective cohort study . European Respiratory Journal 59(5), article number: 2101766. (10.1183/13993003.01766-2021 ) Goulden, N. et al. 2022. Inhaled corticosteroids alone and in combination with long-acting β2 receptor agonists to treat reduced lung function in preterm-born children: a randomized clinical trial . JAMA Pediatrics 176(2), pp. 133-141. (10.1001/jamapediatrics.2021.5111 ) Cousins, M., Hart, K., Gallacher, D., Palomino, M. and Kotecha, S. 2018. Long-term respiratory outcomes following preterm birth . Revista Médica Clínica Las Condes 29(1), pp. 87-97. (10.1016/j.rmclc.2018.02.002 ) Lowe, J., Cousins, M., Kotecha, S. J. and Kotecha, S. 2017. Physical activity outcomes following preterm birth . Paediatric Respiratory Reviews 22, pp. 76-82. (10.1016/j.prrv.2016.08.012 ) Conferences Kotecha, S., Cousins, M., Hart, K., Watkins, W. J. and Kotecha, S. 2022. Effect of IUGR and catch-up growth on later lung function in preterm children: prospective cohort study . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1186., (10.1183/13993003.congress-2022.1186 ) Kotecha, S., Hart, K., Cousins, M., Watkins, W. J., Henderson, A. J. and Kotecha, S. 2022. Association of early life factors with prematurity-associated lung disease : prospective cohort study . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1183., (10.1183/13993003.congress-2022.1183 ) Kotecha, E. et al. 2022. Telomere length in preterm-born children with bronchopulmonary dysplasia (BPD) . Presented at: ERS International Congress, Barcelona, Spain, 4-6 September 2022, Vol. 60. Vol. S66. European Respiratory Society pp. 1292., (10.1183/13993003.congress-2022.1292 ) Thesis