Research
Research interests
I began my PhD at CCMRC in October 2014. I graduated in Rome (Italy) with a Master's degree in Genetics and Molecular Biology. For my thesis I spent two years studying microRNAs as biomarkers for cancer. Then I moved to Liverpool, where I was involved in a project on muscle stem cells. My current work focuses on the epigenetic alteration of human circolating endothelial progenitor cells. I am very grateful to CCMRC for the opportunity they gave me to be a part of the team. I hope to apply my previous experience and improve my skills in the field of cancer research.
Supervisors
Publications
2020
- Zeng, Y. et al. 2020. Identification of DHX36 as a tumour suppressor through modulating the activities of the stress-associated proteins and cyclin-dependent kinases in breast cancer. American Journal of Cancer Research 10(12), pp. 4211-4233.
2018
- Flamini, V., Dudley, E., Jiang, W. G. and Cui, Y. 2018. Distinct mechanisms by which two forms of miR-140 suppress the malignant properties of lung cancer cells. Oncotarget 2018(9) (10.18632/oncotarget.26356)
2017
- Flamini, V., Jiang, W. G. and Cui, Y. 2017. Therapeutic role of MiR-140-5p for the treatment of non-small cell lung cancer. Anticancer Research 37(8), pp. 4319-4327. (10.21873/anticanres.11825)
- Cui, Y., Wu, B., Flamini, V., Evans, B. A., Zhou, D. and Jiang, W. G. 2017. Knockdown of EPHA1 using CRISPR/CAS9 suppresses aggressive properties of ovarian cancer cells. Anticancer Research 37(8), pp. 4415-4424. (10.21873/anticanres.11836)
- Zheng, F., Zhang, Z., Flamini, V., Jiang, W. and Cui, Y. 2017. The axis of CXCR4/SDF-1 plays a role in colon cancer cell adhesion through regulation of the AKT and IGF1R signalling pathways. Anticancer Research 37(8), pp. 4361-4369. (10.21873/anticanres.11830)
- Cui, Y., Bradbury, R., Flamini, V., Wu, B., Jordan, N. and Jiang, W. G. 2017. MicroRNA-7 suppresses the homing and migration potential of human endothelial cells to highly metastatic human breast cancer cells. British Journal of Cancer 117, pp. 89-101. (10.1038/bjc.2017.156)
- Zheng, F., Flamini, V., Bradbury, R., Zhang, Z., Jiang, W. and Cui, Y. 2017. CXCR4 promotes adhesion capacity and activates the AKT signalling pathway in colorectal cancer cells. European Journal of Cancer 72(S1), pp. S68. (10.1016/S0959-8049(17)30302-7)
- Flamini, V. 2017. Role of miR-140-3p and miR-140-5p in lung cancer invasion. PhD Thesis, Cardiff University.
2016
- Flamini, V., Jiang, W. G., Lane, J. and Cui, Y. 2016. Significance and therapeutic implications of endothelial progenitorcells in angiogenic-mediated tumour metastasis. Critical Reviews in Oncology/Hematology 100, pp. 177-189. (10.1016/j.critrevonc.2016.02.010)
- Salvatore, M. et al. 2016. Hepatoblastoma and microRNA-483 two forms and one outcome. Journal of Genetic Syndromes & Gene Therapy 7(1), article number: 278. (10.4172/2157-7412.1000278)
2015
- Cui, Y., Flamini, V. and Jiang, W. G. 2015. Circulating progenitor cells in lung and other cancers. Anticancer Research 35(7), pp. 4317., article number: 67.
- Flamini, V., Jiang, W. G. and Cui, Y. 2015. MIRNA strand selection process in lung cancer. Anticancer Research 35(7), pp. 4349., article number: 136.