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CHRONOS

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We are conducting the qualitative element and longitudinal interviews with patients and clinicians participating in the CHRONOS trial.

Background

This trial is comparing treatment to the whole prostate with treatment to only the areas of cancer in the prostate.

Patients can be assigned to one of two parts of the CHRONOS trial - CHRONOS A or CHRONOS B. They are then randomised to receive a particular therapy.

CHRONOS AFocal therapy alone (High-Intensity Focussed Ultrasound (HIFU) or Cryotherapy) - or radical therapy (removal of the prostate through surgery, radiotherapy or brachytherapy).
CHRONOS BFocal therapy alone or focal therapy in combination with neoadjuvant and/or adjuvant agents i.e. hormone treatment (Finasteride or Bicalutamide).

Patients who participate or decline participation in the trial will be invited to take part in qualitative interviews.

Aim

To explore the patients’ experiences of treatments including side-effects and their quality of life, also patients and clinicians’ perspectives of recruitment to the trial.

Impact

The results from qualitative interviews are fed back to the main trial in real-time.

Taking part

You may be able to join this sub-study if you are eligible for the CHRONOS trial.

Who can’t take part

You cannot take part in the study if you have already had treatment for prostate cancer.

The study is sponsored by Imperial College London.

Information

Chief InvestigatorProfessor Hashim U Ahmed
Qualitative LeadProfessor Annmarie Nelson
Qualitative Study contactDr Mirella Longo
FunderProstate Cancer UK
Start date11 December 2019
End date30 September 2021
StatusCHRONOS A and the qualitative component are open