Ewch i’r prif gynnwys

We seek to foster interactions and stimulate new cross-disciplinary research into innovative and potentially disruptive technological capabilities in biosensing and advanced imaging that will drive world-leading discoveries in the health and life sciences.

As a network our mission is:

  • to facilitate collaboration between researchers across the University through sharing of equipment and expertise
  • to create a platform that will enable the dissemination of our research to academics, industry and stakeholders
  • to promote Cardiff University expertise in biosensing and bioimaging around the world.

Aims

Our specific scientific aims are:

  • To develop novel sensing modalities that employ advances in material science and nanotechnology to   achieve unprecedented functionalities. To develop novel imaging and analytical capabilities which could enable early detection and predictive diagnosis of diseases.
  • To develop novel contrast reagents and chemical probes, improving   delivery technologies, to enhance imaging and sensing capabilities.

Research

We conduct research on:

  • Next-generation optical microscopy instrumentation development.
  • Diagnostic devices with miniaturised light sources and detectors.
  • Chemically sensitive label-free bioimaging of living cells and tissues.
  • Software development for quantitative image analysis.
  • Coherent optical “nanoscopy” of single molecules/particles.
  • Development of new biochemical probes, including engineering of fluorescent proteins.
  • Nanoparticles and functionalised nanostructures for drug delivery.
  • Delivery of small molecule drugs and biopharmaceuticals.
  • Characterizing endocytic pathways for drug delivery research.
  • Production and purification of diamond nanoparticles with single photon centres.

Projects

Examples of projects with the BioSensing and Imaging Network include:

  • EU Marie-Curie ETN Multi-partner Award “Multiphoton Microscopy and Ultrafast Spectroscopy: Imaging meets Quantum (MUSIQ)” (Paola Borri, Wolfgang Langbein,Pete Watson)
  • BBSRC Research Grant Award BB/R021899/1 “A label-free tool to unravel the dynamics of lipid bilayers containing single membrane proteins: iGOR microscopy” (Paola Borri, Wolfgang Langbein, Mark Young)
  • BBSRC Research Grant Award BB/P007511/1“Lipid droplets in oocytes: shedding new light on why fats are good or bad for development” (Karl Swann, Paola Borri, Wolfgang Langbein, Rosalind   John)
  • SerCymru II Rising Star Fellowship “Integrated compound semiconductor lab-on-chip   optical biosensor enabling infectious disease diagnostics at the point-of-care” (Francesco Masia)
  • CRUK/EPSRC project C368/A22099 NS/A000040/1 “Using CARS microscopy to realise the   potential of 3D culture for personalised medicine and drug delivery” (Trevor Dale, Paola Borri, Wolfgang Langbein)
  • EPSRC Research Grant Award EP/R009147/1 “Two-photon Lithography for Isotropic 3D Nanostructure Fabrication” (Sam Ladak, Wolfgang   Langbein, Paola Borri)
  • EPSRC DTP PhD Studentship “Integrated compound semiconductor lab-on-chip optical biosensor”   (Francesco Masia, Wolfgang Langbein, Paola Borri)
  • BBSRC Research Grant award BB/P009980/1 “Traceless, non-invasive and spatiotemporal control of protein activity in cells.” (Louis   Luk, Yuhsuan Tsai, Arwyn T. Jones and Ruedi  Allemann)
  • ERDF, Welsh Government Ireland-Wales INTERREG Operation. Celtic Advanced Life Science Innovation Network. CU Investigators Arwyn T Jones, Mark Gumbleton, James Birchall, Jenna Bowen, Peter. Watson.

Meet the team

Lead researcher

Picture of Paola Borri

Yr Athro Paola Borri

Athro mewn Bioffotoneg (Ffiseg)

Telephone
+44 29208 79356
Email
BorriP@caerdydd.ac.uk

Academic staff

Picture of Trevor Dale

Yr Athro Trevor Dale

Pennaeth Is-adran Biowyddorau Moleciwlaidd

Telephone
+44 29208 74652
Email
DaleTC@caerdydd.ac.uk
Picture of Florian Siebzehnrubl

Dr Florian Siebzehnrubl

Uwch Ddarlithydd, Dirprwy Gyfarwyddwr Sefydliad Ymchwil Bôn-gelloedd Canser Ewrop

Telephone
+44 29206 88500
Email
fas@caerdydd.ac.uk
Picture of Arwyn Jones

Yr Athro Arwyn Jones

Professor of Membrane Traffic and Drug Delivery

Telephone
+44 29208 76431
Email
JonesAT@caerdydd.ac.uk
Picture of Wolfgang Langbein

Yr Athro Wolfgang Langbein

Head of Condensed Matter and Photonics

Telephone
+44 29208 70172
Email
LangbeinWW@caerdydd.ac.uk
Picture of Karl Swann

Yr Athro Karl Swann

Pennaeth Adran Biofeddygaeth

Telephone
+44 29208 79009
Email
SwannK1@caerdydd.ac.uk
Picture of Peter Watson

Yr Athro Peter Watson

Cyfarwyddwr Addysg Ôl-raddedig, Athro, Arweinydd academaidd cyfleusterau delweddu, Cydlynydd Addysgu Ymchwil Ôl-raddedig

Telephone
+44 29208 79042
Email
WatsonPD@caerdydd.ac.uk
Picture of Oliver Williams

Yr Athro Oliver Williams

Cadair
Grŵp Mater Cyddwysedig a Ffotoneg

Telephone
+44 29208 74978
Email
WilliamsO@caerdydd.ac.uk
Picture of Mark Young

Dr Mark Young

Rhaglenni Arwain, Ôl-raddedig a Addysgir

Telephone
+44 29208 79394
Email
YoungMT@caerdydd.ac.uk

Postgraduate students

Picture of Joseph Askey

Dr Joseph Askey

Cydymaith Ymchwil Ôl-ddoethurol

Email
AskeyJW@caerdydd.ac.uk

Associated staff

Picture of Iestyn Pope

Dr Iestyn Pope

Arbenigwr Proffesiynol

Telephone
+44 29208 79037
Email
PopeI@caerdydd.ac.uk

Camau nesaf

academic-school

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Ymchwil ôl-raddedig

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