Cyhoeddiadau

Porwch ein cyhoeddiadau i ddod o hyd i erthyglau, llyfrau, adroddiadau a phapurau a ysgrifennwyd gan arbenigwyr mewn Fferylliaeth a Gwyddorau Fferyllol.

Mae llawer o’n hymchwilwyr yn gwneud eu testun yn gwbl hygyrch er mwyn i bobl ei weld a’i rannu, gan gefnogi arloesedd ymchwil ar raddfa fyd-eang.

Cyhoeddiadau diweddar

Ahmed, Z. et al., 2023. Fraxetin attenuates disrupted behavioral and central neurochemical activity in a model of chronic unpredictable stress. Frontiers in Pharmacology 14 1135497. (10.3389/fphar.2023.1135497)
Ahortor, E. et al., 2023. Virucidal efficacy of gaseous ozone against type 1 herpes simplex virus (hsv-1). Ozone: Science & Engineering (10.1080/01919512.2023.2231037)
Alablani, D. 2023. Acute arterial hypoxaemia and its impact on drug pharmacokinetics in humans; clinical and in-vitro investigation. PhD Thesis , Cardiff University.
Alghamdi, R. 2023. The synthesis of a charge-based conjugation system to extend the intra-articular resident time of osteoarthritis therapeutics. PhD Thesis , Cardiff University.
Alle, T. et al., 2023. Microtubule-stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as candidate therapeutics for neurodegenerative disease: Matched molecular pair analyses and computational studies reveal new structure-activity insights. Journal of Medicinal Chemistry 66 (1), pp.435-459. (10.1021/acs.jmedchem.2c01411)
Almehdi, A. M. et al., 2023. Design, synthesis, and potent anticancer activity of novel indole-based Bcl-2 inhibitors. International Journal of Molecular Sciences 24 (19) 14656. (10.3390/ijms241914656)
Alotaibi, M. M. , Hughes, L. and Ford, W. R. 2023. Assessing inhaler techniques of asthma patients using aerosol inhalation monitors (aim): a cross-sectional study. Healthcare 11 (8) 1125. (10.3390/healthcare11081125)
Alsaqati, M. , Thomas, R. S. and Kidd, E. J. 2023. Upregulation of endocytic protein expression in the Alzheimer's disease male human brain. Aging Brain 4 100084. (10.1016/j.nbas.2023.100084)
Alshabani, L. 2023. Targeting Mycobacterium tuberculosis: Design and synthesis of CYP121A1 inhibitors. PhD Thesis , Cardiff University.
Alyahya, K. and Baillie, L. 2023. Assessing the feasibility of employing a combination of a bacteriophage-derived endolysin and spore germinants to treat relapsing clostridioides difficile infection. Microorganisms 11 (7) 1651. (10.3390/microorganisms11071651)
Alzahrani, A. 2023. Biochemical investigation of zinc transporters to discover their functional mechanism in cells. PhD Thesis , Cardiff University.
Andrews, R. et al. 2023. Does Health & Her app use improve menopausal symptoms? A longitudinal cohort study. BMJ Open 13 (12) e077185. (10.1136/bmjopen-2023-077185)
Aske, R. 2023. Impact of photodynamic therapy on different breast cancer subtypes in-vitro. PhD Thesis , Cardiff University.
Avigliano, M. 2023. Design, synthesis and evaluation of novel immune checkpoint small molecule inhibitors as potential cancer treatment. PhD Thesis , Cardiff University.
Baptista, R. , Williams, M. and Price, J. 2023. Improving the impact of pharmacy interventions in hospitals. BMJ Open Quality 12 (4) e002276. (10.1136/bmjoq-2023-002276)
Beresford, M. et al., 2023. Fulvestrant plus vandetanib versus placebo for the treatment of patients with metastatic breast cancer resistant to aromatase inhibitor therapy (FURVA): a multicentre, Phase 2, randomised controlled trial. BJC Reports 1 (1) 13. (10.1038/s44276-023-00016-8)
Best, H. L. et al. 2023. The role of glycoconjugates as receptors for insecticidal proteins. FEMS Microbiology Reviews 47 (4)(10.1093/femsre/fuad026)
Bethel, N. et al., 2023. Precisely patterned nanofibres made from extendable protein multiplexes. Nature Chemistry 15 (Decemb), pp.1664-1671. (10.1038/s41557-023-01314-x)
Birch, D. et al., 2023. Stereoisomer-dependent membrane association and capacity for insulin delivery facilitated by Penetratin. Pharmaceutics 15 (6) 1672. (10.3390/pharmaceutics15061672)
Bojan, B. 2023. Risk factors in prosthetic hip/knee joint replacement infections incidence and patient outcomes. PhD Thesis , Cardiff University.
Boulet, M. et al., 2023. Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase. eLife 12 RP91655. (10.7554/elife.91655)
Broadley, K. J. and Mehta, D. 2023. Trace amine-induced vasoconstriction of human mammary artery and saphenous vein. Vascular Pharmacology 151 107191. (10.1016/j.vph.2023.107191)
Caldwell, N. et al., 2023. Perspective on schistosomiasis drug discovery: highlights from a schistosomiasis drug discovery workshop at Wellcome Collection, London, September 2022. ACS Infectious Diseases 9 (5), pp.1046-1055. (10.1021/acsinfecdis.3c00081)
Cartmell, D. 2023. Polymer sorbent materials for the extraction of organic compounds. PhD Thesis , Cardiff University.
Centeleghe, I. et al. 2023. Klebsiella pneumoniae survives on surfaces as a dry biofilm. American Journal of Infection Control 51 (10), pp.1157-1162. (10.1016/j.ajic.2023.02.009)
Chakroborty, A. et al., 2023. Modified hederagenin derivatives demonstrate ex vivo anthelmintic activity against fasciola hepatica. Pharmaceutics 15 (7) 1869. (10.3390/pharmaceutics15071869)
Cropley, V. et al., 2023. Complement proteins are elevated in blood serum but not CSF in clinical high-risk and antipsychotic-naïve first-episode psychosis. Brain, Behavior, and Immunity 113 , pp.136-144. (10.1016/j.bbi.2023.07.004)
Daniele, R. et al., 2023. Influence of folate-targeted gold nanoparticles on subcellular localization and distribution into lysosomes. Pharmaceutics 15 (3) 864. (10.3390/pharmaceutics15030864)
Doganay, M. et al., 2023. Human anthrax: Update of the diagnosis and treatment. Diagnostics 13 (6) 1056. (10.3390/diagnostics13061056)
Duggan, K. et al. 2023. Evaluating the antimicrobial efficacy of long-lasting hand sanitisers on skin. Journal of Hospital Infection (10.1016/j.jhin.2023.08.020)
Dul, M. et al. 2023. Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product. Journal of Controlled Release 361 , pp.236-245. (10.1016/j.jconrel.2023.07.001)
Eissa, A. G. et al. 2023. Pyridine based dual binding site aromatase (CYP19A1) inhibitors. RSC Medicinal Chemistry 14 (2), pp.356-366. (10.1039/d2md00352j)
Elbaramawi, S. S. et al., 2023. Exploring Proteus mirabilis methionine tRNA synthetase active site: homology model construction, molecular dynamics, pharmacophore and docking validation. Pharmaceuticals 16 (9) 1263. (10.3390/ph16091263)
Farr, G. , Jones, S. and Taylor, K. M. 2023. Methods to visualise zinc transporter proteins of the SLC39A family in cells [Chapter 4]. In: Hu, J. ed. Methods in Enzymology. Vol. 687, Elsevier. , pp.67-85. (10.1016/bs.mie.2023.04.020)
Ferdinandy, P. et al., 2023. Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological treatments and ischemic conditioning. Pharmacological Reviews 75 (1), pp.159-216. (10.1124/pharmrev.121.000348)
Francisco, K. R. et al., 2023. Targeted reversible covalent modification of a noncatalytic lysine of the Krev interaction trapped 1 protein enables site-directed screening for protein-protein interaction inhibitors. ACS Pharmacology & Translational Science 6 (11), pp.1651-1658. (10.1021/acsptsci.3c00156)
Giacobbe, D. R. et al., 2023. Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG. Critical Care 27 (1) 323. (10.1186/s13054-023-04608-1)
Gohar, A. et al., 2023. Effect of Gabapentin-Fluoxetine Derivative GBP1F in a murine model of depression, anxiety and cognition. Drug Design, Development and Therapy 17 , pp.1793-1803. (10.2147/DDDT.S407229)
Gruden, M. A. et al., 2023. Analysis of NAPA gene expression in brain structures of Wistar Rats during the formation of long-term spatial memory and physical activity under stress situation. Bulletin of Experimental Biology and Medicine 175 (6), pp.810-813. (10.1007/s10517-023-05952-6)
Gushchina, V. et al., 2023. The calcium-sensing receptor modulates the prostaglandin E 2 pathway in intestinal inflammation. Frontiers in Pharmacology 14 1151144. (10.3389/fphar.2023.1151144)
Heurich, M. and McCluskey, G. 2023. Complement and coagulation crosstalk - Factor H in the spotlight. Immunobiology 228 (6) 152707. (10.1016/j.imbio.2023.152707)
Hunter, M. R. et al., 2023. Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles. small methods 2201695. (10.1002/smtd.202201695)
Intabli, H. et al., 2023. Glucocorticoid induced loss of oestrogen receptor alpha gene methylation and restoration of sensitivity to fulvestrant in triple negative breast cancer. Gene 851 147022. (10.1016/j.gene.2022.147022)
James, D. H. et al., 2023. Development of a questionnaire to measure public perceptions of the role of community pharmacy in public health ( PubPharmQ ). Pharmacy 11 (5) 141. (10.3390/pharmacy11050141)
James, R. et al. 2023. Exploring the implementation of Discharge Medicines Review referrals by hospital pharmacy professionals: A qualitative study using the consolidated framework for implementation research. Research in Social and Administrative Pharmacy 19 (12), pp.1558-1569. (10.1016/j.sapharm.2023.08.006)
Juraybi, T. 2023. Screening honey for antibacterial activity against acinetobacter baumannii. PhD Thesis , Cardiff University.
Lambourne, O. A. et al. 2023. PINK1-Dependent mitophagy inhibits elevated ubiquitin phosphorylation caused by mitochondrial damage. Journal of Medicinal Chemistry 66 (11), pp.7645-7656. (10.1021/acs.jmedchem.3c00555)
Larissa, P. et al., 2023. Development, characterization and antimicrobial activity of multilayer silica nanoparticles with chlorhexidine incorporated into dental composites. Dental Materials 39 (5), pp.469-477. (10.1016/j.dental.2023.03.005)
Lelos, M. J. et al. 2023. Impaired cognitive and motor function are coincident with l -DOPA-induced dyskinesia in a model of Parkinson’s disease. Scientific Reports 13 17697. (10.1038/s41598-023-44869-y)
Li, Z. et al., 2023. Low‐field actuating magnetic elastomer membranes characterized using fibre‐optic interferometry. Advanced Functional Materials 33 (50) 2301857. (10.1002/adfm.202301857)
Lown, M. et al., 2023. Internet tool to support self-assessment and self-swabbing of sore throat: Development and feasibility study. Journal of Medical Internet Research 25 e39791. (10.2196/39791)
Maillard, J. and Centeleghe, I. 2023. How biofilm changes our understanding of cleaning and disinfection. Antimicrobial Resistance and Infection Control 12 (1) 95. (10.1186/s13756-023-01290-4)
Manoharan, S. et al., 2023. From cereus to anthrax and back again: Assessment of the temperature-dependent phenotypic switching in the "cross-over" strain Bacillus cereus G9241. Frontiers in Microbiology 14 (10.3389/fmicb.2023.1113562)
Mantzourani, E. et al. 2023. Development, implementation and evaluation of the digital transformation of renal services in Wales: the journey from local to national. International Journal of Clinical Pharmacy 45 , pp.4-16. (10.1007/s11096-022-01466-9)
Mantzourani, E. et al. 2023. Community pharmacists? Views on the early stages of implementation of a national pilot independent prescribing service in wales: a qualitative study. Integrated Pharmacy Research and Practice 12 , pp.11-23. (10.2147/IPRP.S395322)
Mantzourani, E. et al. 2023. Characteristics of the sore throat test and treat service in community pharmacies (STREP) in Wales: cross-sectional analysis of 11304 consultations using anonymized electronic pharmacy records,. Journal of Antimicrobial Chemotherapy 78 (1), pp.84-92. (10.1093/jac/dkac358)
Matuttis, H. et al., 2023. Computational investigation of the clustering of droplets in widening pipe geometries. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.82-93. (10.1007/978-3-031-31183-3_7)
Mehellou, Y. 2023. Parkinson's disease: are PINK1 activators inching closer to the clinic?. ACS Medicinal Chemistry Letters 14 (7), pp.870-874. (10.1021/acsmedchemlett.3c00070)
Mitchell, B. G. et al., 2023. Risk of organism acquisition from prior room occupants: An updated systematic review. Infection, Disease & Health 28 (4), pp.290-297. (10.1016/j.idh.2023.06.001)
Monti, L. et al., 2023. Structure‐activity relationships, tolerability and efficacy of microtubule‐active 1,2,4‐Triazolo[1,5‐ a ]pyrimidines as potential candidates to treat human African trypanosomiasis. ChemMedChem 18 (20) e202300193. (10.1002/cmdc.202300193)
Moukachar, A. et al. 2023. Development and evaluation of a low‐cost lego 3d bioprinter: from building‐blocks to building blocks of life. Advanced Materials Technologies 8 (6) 2100868. (10.1002/admt.202100868)
Muir, D. , Richards, C. and John, D. N. 2023. Longer-term outcomes of medicine and pharmacy students at Cardiff University after undergraduate therapeutics and prescribing interprofessional education. Pharmacy Education 23 (1), pp.584-593. (10.46542/pe.2023.231.584593)
Padalino, G. et al. 2023. Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes. Wellcome Open Research 8 146. (10.12688/wellcomeopenres.18826.1)
Padalino, G. et al. 2023. Using ChEMBL to complement schistosome drug discovery. Pharmaceutics 15 (5) 1359. (10.3390/pharmaceutics15051359)
Pasqualetto, G. et al. 2023. Identification of a novel P2X7 antagonist using structure-based virtual screening. Frontiers in Pharmacology 13 1094607. (10.3389/fphar.2022.1094607)
Pasqualetto, G. et al. 2023. Identification of the molecular determinants of antagonist potency in the allosteric binding pocket of human P2X4. Frontiers in Pharmacology 14 (10.3389/fphar.2023.1101023)
Perni, S. , Bojan, B. and Prokopovich, P. 2023. A retrospective study of risk factors, causative micro-organisms and healthcare resources consumption associated with prosthetic joint infections (PJI) using the Clinical Practice Research Datalink (CPRD) Aurum database. PLoS ONE 18 (3) e0282709. (10.1371/journal.pone.0282709)
Queirós-Reis, L. et al., 2023. Exploring the fatty acid binding pocket in the SARS-CoV-2 spike protein - confirmed and potential ligands. Journal of Chemical Information and Modeling 63 (23), pp.7282–7298. (10.1021/acs.jcim.3c00803)
Rizzo, S. 2023. Development of glucose releasing biomaterials for applications in cell therapies. PhD Thesis , Cardiff University.
Robertson, A. 2023. Understanding the risk of emerging bacterial resistance from the use of sore throat over-the-counter topical antibiotics. PhD Thesis , Cardiff University.
Saeedi, T. 2023. Emulsion assisted nonsteroidal anti-inflammatory drug delivery system for the osteoarthritis treatment. PhD Thesis , Cardiff University.
Salerno, M. et al., 2023. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. European Journal of Medicinal Chemistry 246 114942. (10.1016/j.ejmech.2022.114942)
Sayour, N. V. et al., 2023. Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study. Cardiovascular Research cvad024. (10.1093/cvr/cvad024)
Schneider, J. J. et al., 2023. Artificial chemistry performed in an agglomeration of droplets with restricted molecule transfer. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation.. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.107-118. (10.1007/978-3-031-31183-3_9)
Serpi, M. et al. 2023. Synthesis, molecular docking and antibacterial activity of an oxadiazole-based lipoteichoic acid inhibitor and its metabolites. Journal of Molecular Structure 1278 134977. (10.1016/j.molstruc.2023.134977)
Smith, J. et al., 2023. Using the theoretical domains framework to determine the barriers and facilitators to medication adherence in Parkinson's disease. Exploratory Research in Clinical and Social Pharmacy 11 100309. (10.1016/j.rcsop.2023.100309)
Susai, S. R. et al., 2023. Association of complement and coagulation pathway proteins with treatment response in first-episode psychosis: a longitudinal analysis of the OPTiMiSE clinical trial. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders 49 (4), pp.893-902. (10.1093/schbul/sbac201)
Taylor, K. M. 2023. The liv-1 subfamily of zinc transporters: from origins to present day discoveries. International Journal of Molecular Sciences 24 (2) 1255. (10.3390/ijms24021255)
Taylor-Joyce, G. et al., 2023. The influence of extrachromosomal elements in the anthrax “cross-over” strain Bacillus cereus G9241. Frontiers in Microbiology 14 1113642. (10.3389/fmicb.2023.1113642)
Thomas, N. L. , Dart, C. and Helassa, N. 2023. Editorial: The role of calcium and calcium binding proteins in cell physiology and disease. Frontiers in Physiology 14 1228885. (10.3389/fphys.2023.1228885)
Tokhi, A. et al., 2023. Effects of 1-methyl-1, 2, 3, 4-tetrahydroisoquinoline on a diabetic neuropathic pain model. Frontiers in Pharmacology 14 1128496. (10.3389/fphar.2023.1128496)
Usman, M. et al., 2023. 5,7-Dimethoxycoumarin ameliorates vincristine induced neuropathic pain: potential role of 5HT 3 receptors and monoamines. Frontiers in Pharmacology 14 1213763. (10.3389/fphar.2023.1213763)
Wale, A. et al. 2023. Factors affecting the patient journey and patient care when receiving an unlicensed medicine: A systematic review. Research in Social and Administrative Pharmacy 19 (7), pp.1025-1041. (10.1016/j.sapharm.2023.04.120)
Wang, Y. , Bastiancich, C. and Newland, B. 2023. Injectable local drug delivery systems for glioblastoma: a systematic review and meta -analysis of progress to date †. Biomaterials Science (10.1039/d2bm01534j)
Wilson-Garner, S. , Baillie, L. and Porch, A. 2023. Increasing sample volume for microwave-assisted rapid DNA release. Presented at: 2022 Asia-Pacific Microwave Conference (APMC) Yokohama, Japan 29 November 2022 - 02 December 2022. Proceedings of 2022 Asia-Pacific Microwave Conference (APMC). IEEE. , pp.638-640. (10.23919/APMC55665.2022.10000050)
Xiang, H. et al., 2023. Biocatalytic and chemo-enzymatic synthesis of quinolines and 2‑quinolones by monoamine oxidase (MAO-N) and horseradish peroxidase (HRP) biocatalysts. ACS Catalysis 13 (5), pp.3370-3378. (10.1021/acscatal.2c05902)
Yang, L. et al. 2023. Nanocomposite orthopaedic bone cement combining long-acting dual antimicrobial drugs. Biomaterials Advances 153 213538. (10.1016/j.bioadv.2023.213538)
Zawal, A. G. et al., 2023. Targeting Mycobacterium tuberculosis: synthesis, in vitro and in silico evaluation of novel N1-(benzo[d]oxazol-2-yl)-N4-arylidine compounds. Archiv der Pharmazie 356 (8) 2300187. (10.1002/ardp.202300187)