Dr Natacha Ipseiz

2023

• Mazzarino, M. et al. 2023. Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology. Frontiers in Immunology 14, article number: 1240679. (10.3389/fimmu.2023.1240679)

2022

• Czubala, M. A. et al. 2022. 3R Blackboard: A platform for animal and organ sharing. Laboratory Animals 56(3), pp. 292-296. (10.1177/00236772211067456)

2021

• Faas, M. et al. 2021. IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation. Immunity 54(11), pp. 2531-2546. (10.1016/j.immuni.2021.09.010)
• Bohaud, C., Johansen, M. D., Jorgensen, C., Kremer, L., Ipseiz, N. and Djouad, F. 2021. The role of macrophages during zebrafish injury and tissue regeneration under infectious and non-infectious conditions. Frontiers in Immunology 12, article number: 707856. (10.3389/fimmu.2021.707824)
• Bohaud, C., Johansen, M. D., Jorgensen, C., Kremer, L., Ipseiz, N. and Djouad, F. 2021. The role of macrophages during mammalian tissue remodeling and regeneration under infectious and non-infectious conditions. Frontiers in Immunology 12, article number: 707856. (10.3389/fimmu.2021.707856)
• Bart, V. M. T., Pickering, R. J., Taylor, P. R. and Ipseiz, N. 2021. Macrophage reprogramming for therapy. Immunology 163(2), pp. 128-144. (10.1111/imm.13300)

2020

• Ipseiz, N. et al. 2020. Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway. EMBO Journal 39(14), article number: e103454. (10.15252/embj.2019103454)
• Müller, D. I. H. et al. 2020. PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass. Scientific Reports 10, article number: 8428. (10.1038/s41598-020-65305-5)
• Ipseiz, N., Czubala, M. A., Bart, V. M., Davies, L. C., Jenkins, R. H., Brennan, P. and Taylor, P. R. 2020. Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors. Molecular Therapy - Methods and Clinical Development 16, pp. 21-31. (10.1016/j.omtm.2019.10.004)

2018

• Scholtysek, C. et al. 2018. NR4A1 regulates motility of osteoclast precursors and serves as target for the modulation of systemic bone turnover. Journal of Bone and Mineral Research 33(11), pp. 2035-2047. (10.1002/jbmr.3533)
• Luo, Y. et al. 2018. Fra-2 expression in osteoblasts regulates systemic inflammation and lung injury through osteopontin. Molecular and Cellular Biology 38(22), article number: e00022-18. (10.1128/MCB.00022-18)
• Haberland, K. et al. 2018. Eosinophils are not essential for maintenance of murine plasma cells in the bone marrow. European Journal of Immunology 48(5), pp. 822-828. (10.1002/eji.201747227)
• Luz-Crawford, P. et al. 2018. Gilz-Activin A as a novel signaling axis orchestrating mesenchymal stem cell and Th17 cell interplay. Theranostics 8(3), pp. 846-859. (10.7150/thno.21793)

2017

• Stock, M. et al. 2017. Corrigendum to “Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis” (Osteoarthritis Cartilage (2015) 23(7) (1221–1225) (S1063458415000631) (10.1016/j.joca.2015.02.019)). Osteoarthritis and Cartilage 25(6), pp. 995. (10.1016/j.joca.2016.11.003)
• Djouad, F., Ipseiz, N., Luz-Crawford, P., Scholtysek, C., Kroenke, G. and Jorgensen, C. 2017. PPARβ/δ: A master regulator of mesenchymal stem cell functions. Biochimie 136, pp. 55-58. (10.1016/j.biochi.2016.11.011)
• Rothe, T. et al. 2017. The nuclear receptor Nr4a1 acts as a microglia rheostat and serves as a therapeutic target in autoimmune-driven central nervous system inflammation. Journal of Immunology 198(10), pp. 3878-3885. (10.4049/jimmunol.1600638)
• Pfeifle, R. et al. 2017. Novel mechanism mediated by the IL23/TH17 axis contributing to auto-immune arthritis. Annals of the Rheumatic Diseases 76, pp. A6-A7. (10.1136/annrheumdis-2016-211048.14)
• Pfeifle, R. et al. 2017. Regulation of autoantibody activity by the IL-23-T(H)17 axis determines the onset of autoimmune disease. Nature Immunology 18(1), pp. 104-113. (10.1038/ni.3579)

2016

• Luz-Crawford, P. et al. 2016. PPAR beta/delta directs the therapeutic potential of mesenchymal stem cells in arthritis. Annals of the Rheumatic Diseases 75(12), pp. 2166-2174. (10.1136/annrheumdis-2015-208696)
• Pfeifle, R. et al. 2016. Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease. Nature Immunology 18(1), pp. 104-113. (10.1038/ni.3579)
• Luz-Crawford, P. et al. 2016. PPARβ/δ directs the therapeutic potential of mesenchymal stem cells in arthritis. Annals of the Rheumatic Diseases 75(12), pp. 2166-2174. (10.1136/annrheumdis-2015-208696)
• Pfeifle, R., Rothe, T., Ipseiz, N., Culemann, S., Harre, U., Kroenke, G. and Schett, G. 2016. Novel mechanism mediated by the IL-23/Th17 axis contributing to auto-immune arthritis. Arthritis and Rheumatology 68

2015

• Luo, Y. et al. 2015. Microbiota from obese mice regulate hematopoietic stem cell differentiation by altering the bone niche. Cell Metabolism 22(5), pp. 886-894. (10.1016/j.cmet.2015.08.020)
• Stock, M. et al. 2015. Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis. Osteoarthritis and Cartilage 23(7), pp. 1221-1225. (10.1016/j.joca.2015.02.019)
• Rothe, T. et al. 2015. 12/15-lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. The Journal of Clinical Investigation 125(5), pp. 1944-1954. (10.1172/JCI78490)

2014

• Kienhöfer, D. et al. 2014. No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis. PLoS ONE 9(12), article number: e115474. (10.1371/journal.pone.0115474)
• Ipseiz, N., Scholtysek, C., Culemann, S. and Krönke, G. 2014. Adopted orphans as regulators of inflammation, immunity and skeletal homeostasis. Swiss Medical Weekly 144, article number: w14055. (10.4414/smw.2014.14055)
• Ipseiz, N. et al. 2014. The nuclear receptor Nr4a1 mediates anti-inflammatory effects of apoptotic cells. The Journal of Immunology 192(10), pp. 4852-4858. (10.4049/jimmunol.1303377)

2013

• Scholtysek, C. et al. 2013. PPARβ/δ governs Wnt signaling and bone turnover. Nature Medicine 19(5), pp. 608-613. (10.1038/nm.3146)

2012

• Harre, U. et al. 2012. Moonlighting osteoclasts as undertakers of apoptotic cells. Autoimmunity 45(8), pp. 612-619. (10.3109/08916934.2012.719950)
• Uderhardt, S. et al. 2012. 12/15-Lipoxygenase Orchestrates the Clearance of Apoptotic Cells and Maintains Immunologic Tolerance. Immunity 36(5), pp. 834-846. (10.1016/j.immuni.2012.03.010)