Dr Patrick Van Eijk

2024

• Mackay, H. L. et al. 2024. USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication. Nature Communications 15, article number: 8102. (10.1038/s41467-024-52250-4)

2023

• Newton, M. D. et al. 2023. Negative DNA supercoiling induces genome-wide Cas9 off-target activity. Molecular Cell 83(19), pp. 3533-3545.e5. (10.1016/j.molcel.2023.09.008)
• Yancoskie, M. N., Maritz, C., van Eijk, P., Reed, S. H. and Naegeli, H. 2023. To incise or not and where: SET-domain methyltransferases know. Trends in Biochemical Sciences 48(4), pp. 321-330. (10.1016/j.tibs.2022.10.003)

2022

• Murat, P., Perez, C., Crisp, A., van Eijk, P., Reed, S. H., Guilbaud, G. and Sale, J. E. 2022. DNA replication initiation shapes the mutational landscape and expression of the human genome. Science Advances 8(45) (10.1126/sciadv.add3686)
• Dobbs, F. M., van Eijk, P., Fellows, M. D., Loiacono, L., Nitsch, R. and Reed, S. H. 2022. Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq. Nature Communications 13, article number: 3989. (10.1038/s41467-022-31702-9)

2017

• Van Eijk, P., Teng, Y., Bennet, M. R., Evans, K., Powell, J. R., Webster, R. and Reed, S. 2017. Integrated microarray-based tools for detection of genomic DNA damage and repair mechanisms. In: Muzi-Falconi, M. and Brown, G. W. eds. Genome Instability. Methods in Molecular Biology., Vol. 1672. New York, NY: Humana Press, pp. 77., (10.1007/978-1-4939-7306-4_7)

2016

• Yu, S. et al. 2016. Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin. Genome Research 26, pp. 1376-1387. (10.1101/gr.209106.116)

2015

• Waters, R., van Eijk, P. and Reed, S. 2015. Histone modification and chromatin remodeling during NER. DNA Repair 36, pp. 105-113. (10.1016/j.dnarep.2015.09.013)
• Zhou, Z. et al. 2015. UV induced ubiquitination of the yeast Rad4–Rad23 complex promotes survival by regulating cellular dNTP pools. Nucleic Acids Research 43(15), pp. 7360-7370. (10.1093/nar/gkv680)

2008

• den Dulk, B., van Eijk, P., de Ruijter, M., Brandsma, J. A. and Brouwer, J. 2008. The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4. DNA Repair 7(6), pp. 858-868. (10.1016/j.dnarep.2008.02.004)