Dr Simone Cuff

2024

• Burton, R. J. et al. 2024. Conventional and unconventional T cell responses contribute to the prediction of clinical outcome and causative bacterial pathogen in sepsis patients. Clinical & Experimental Immunology 216(3), pp. 293-306. (10.1093/cei/uxae019)
• Tyler, C. J. et al. 2024. IL-21 conditions antigen-presenting human γδ T-cells to promote IL-10 expression in naïve and memory CD4+ T-cells. Discovery Immunology (10.1093/discim/kyae008)

2023

• Cuff, S. et al. 2023. Inflammatory biomarker signatures in post-surgical drain fluid may detect anastomotic leaks within 48 hours of colorectal resection. Techniques in Coloproctology (10.1007/s10151-023-02841-y)
• Burton, R. J., Cuff, S. M., Morgan, M. P., Artemiou, A. and Eberl, M. 2023. GeoWaVe: Geometric median clustering with weighted voting for ensemble clustering of cytometry data. Bioinformatics 39(1), article number: btac751. (10.1093/bioinformatics/btac751)

2022

• Cuff, S. M., Merola, J. P., Eberl, M. and Gray, W. P. 2022. Presence of ventriculoperitoneal and lumbar shunts stimulate long lasting non-inflammatory changes in the cerebrospinal fluid distinct from the response to bacterial infection. [Online]. medRxiv. (10.1101/2022.10.12.22280998) Available at: https://doi.org/10.1101/2022.10.12.22280998
• Ponsford, M. J. et al. 2022. Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation. Journal of Clinical Pathology 75(4), pp. 255-262. (10.1136/jclinpath-2020-207157)

2021

• Burton, R. J., Ahmed, R., Cuff, S. M., Baker, S., Artemiou, A. and Eberl, M. 2021. CytoPy: An autonomous cytometry analysis framework. PLoS Computational Biology 17(6), article number: e1009071. (10.1371/journal.pcbi.1009071)
• Reeves, N. et al. 2021. Diagnosis of colorectal and emergency surgical site infections in the era of enhanced recovery: an all-Wales prospective study. Colorectal Disease 23(55), pp. 1239-1247. (10.1111/codi.15569)

2020

• Cuff, S. M., Merola, J. P., Twohig, J. P., Eberl, M. and Gray, W. P. 2020. Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation. Brain Communications 2(2), article number: fcaa218. (10.1093/braincomms/fcaa218)
• Catar, R. A. et al. 2020. Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL‐17 and IFN‐γ. Journal of Pathology 251(2), pp. 175-186. (10.1002/path.5438)

2019

• Gadalla, A. A. M. et al. 2019. Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms. Scientific Reports 9(1), article number: 19694. (10.1038/s41598-019-55523-x)
• Burton, R. J., Albur, M., Eberl, M. and Cuff, S. M. 2019. Using artificial intelligence to reduce diagnostic workload without compromising detection of urinary tract infections. BMC Medical Informatics and Decision Making 19(1), article number: 171. (10.1186/s12911-019-0878-9)
• Brook, A. C. et al. 2019. Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis. Scientific Reports 9, article number: 10136. (10.1038/s41598-019-46585-y)
• Pearson, J. A. et al. 2019. Altered gut microbiota activate and expand insulin B15-23-Reactive CD8+ T-Cells. Diabetes 68(5), pp. 1002-1013. (10.2337/db18-0487)

2018

• Cuff, S., Lewis, R. D., Chinje, E., Jaffar, M., Knox, R. and Weeks, I. 2018. An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive test for NAD(P)H quinone oxidoreductase 1 (NQO1) in living cells. Free Radical Biology and Medicine 116, pp. 141-148. (10.1016/j.freeradbiomed.2018.01.009)

2015

• Stack, G. et al. 2015. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathogens 11(2), article number: e1004641. (10.1371/journal.ppat.1004641)

2014

• Fielding, C. A. et al. 2014. Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation. PLoS Pathogens 10(5), article number: e1004058. (10.1371/journal.ppat.1004058)

2012

• Fielding, C. A. et al. 2012. A novel human cytomegalovirus gene function targets the natural killer cell activating ligand MICA for lysosomal degradation [Abstract]. Immunology 137(S1), pp. 154. (10.1111/imm.12001)
• Twohig, J. P. et al. 2012. The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity. The FASEB Journal 26(8), pp. 3575-3586. (10.1096/fj.11-200618)
• Prod'homme, V. et al. 2012. Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18. The Journal of Immunology 188(6), pp. 2794-2804. (10.4049/jimmunol.1102068)

2010

• Twohig, J. P. et al. 2010. Age-dependent maintenance of motor controland corticostriatal innervation by death receptor 3. Journal of Neuroscience 30(10), pp. 3782-3792. (10.1523/JNEUROSCI.1928-09.2010)
• Cuff, S., Dolton, G. M., Matthews, R. J. and Gallimore, A. M. 2010. Antigen specificity determines the pro- or antitumoral nature of CD8+ T cells. The Journal of Immunology 184(2), pp. 607-614. (10.4049/jimmunol.0804089)