Dr Jan Bondeson

2013

• Wainwright, S. D., Bondeson, J., Caterson, B. and Hughes, C. E. 2013. ADAMTS4_v1 is a splice variant of ADAMTS4 that is expressed as a protein in human synovium and cleaves aggrecan at the interglobular domain. Arthritis & Rheumatism 65(11), pp. 2866-2875. (10.1002/art.38102)
• Bondeson, J., Wainwright, S. D., Caterson, B. and Hughes, C. E. 2013. ADAMTS4. In: Rawlings, N. D. and Salvesen, G. eds. Handbook of Proteolytic Enzymes. 3rd ed.., Vol. 1. London: Academic Press, pp. 1166-1173., (10.1016/B978-0-12-382219-2.00262-3)
• Bondeson, J., Wainwright, S. D., Caterson, B. and Hughes, C. E. 2013. ADAMTS5. In: Rawlings, N. D. and Salvesen, G. eds. Handbook of Proteolytic Enzymes. 3rd ed.., Vol. 1. London: Academic Press, pp. 1174-1180., (10.1016/B978-0-12-382219-2.00263-5)

2012

• Wainwright, S. D., Bondeson, J., Hughes, C. E. and Caterson, B. 2012. Human osteoarthritis synovium contains an alternatively spliced transcript of ADAMTS4 [Abstract]. Osteoarthritis and Cartilage 20(S1), pp. S136. (10.1016/j.joca.2012.02.185)

2010

• Bondeson, J., Blom, A. B., Wainwright, S. D., Hughes, C., Caterson, B. and van den Berg, W. B. 2010. The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis & Rheumatism 62(3), pp. 647-657. (10.1002/art.27290)
• Bondeson, J. 2010. Activated Synovial Macrophages as Targets for Osteoarthritis Drug Therapy. Current Drug Targets 11(5), pp. 576-585. (10.2174/138945010791011965)

2008

• Bondeson, J., Wainwright, S. D., Hughes, C. E. and Caterson, B. 2008. The regulation of ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review. Clinical and Experimental Rheumatology 26(1), pp. 139-145.

2007

• Bondeson, J. et al. 2007. Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent. The Journal of Rheumatology 34(3), pp. 523-533.
• Lauder, S. N. et al. 2007. Interleukin-1β induced activation of nuclear factor-κb can be inhibited by novel pharmacological agents in osteoarthritis. Rheumatology 46(5), pp. 752-758. (10.1093/rheumatology/kel419)

2006

• Bondeson, J., Wainwright, S. D., Lauder, S. N., Amos, N. and Hughes, C. E. 2006. The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis. Arthritis Research and Therapy 8(6), pp. 187-199. (10.1186/ar2099)
• Amos, N., Lauder, S. N., Evans, A., Feldmann, M. and Bondeson, J. 2006. Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent. Rheumatology 45(10), pp. 1201-1209. (10.1093/rheumatology/kel078)
• Wainwright, S. D., Bondeson, J. and Hughes, C. E. 2006. An alternative spliced transcript of ADAMTS4 is present in human synovium from OA patients. Matrix Biology 25(5), pp. 317-320. (10.1016/j.matbio.2006.03.006)

2005

• Jones, G. L., Lukaris, A. D., Prabhu, H. V., Brown, M. J. K. M. and Bondeson, J. 2005. Wegener’s granulomatosis mimicking a parotid abscess. The Journal of Laryngology & Otology 119(9), pp. 746-749. (10.1258/0022215054797952)

2004

• Jewell, D. P. A., Thompson, I. W., Sullivan, B. A. and Bondeson, J. 2004. Reversible focal myositis in a patient taking venlafaxine. Rheumatology 43(12), pp. 1590-1593. (10.1093/rheumatology/keh420)

2003

• Thurairajah, P., Browne, S. and Bondeson, J. 2003. A painful swollen calf. Journal of the Royal Society of Medicine 96(5), pp. 236-237.
• Calder, V. L., Bondeson, J., Brennan, F. M., Foxwell, B. M. J. and Feldmann, M. 2003. Antigen-specific T-Cell downregulation by human dendritic cells following blockade of NF-kappaB. Scandinavian Journal of Immunology 57(3), pp. 261-270. (10.1046/j.1365-3083.2003.01228.x)
• Yoshimura, S., Bondeson, J., Brennan, F. M., Foxwell, B. M. J. and Feldmann, M. 2003. Antigen presentation by murine dendritic cells is nuclear factor-kappa B dependent both in vitro and in vivo. Scandinavian Journal of Immunology 58(2), pp. 165-172. (10.1046/j.1365-3083.2003.01246.x)

2002

• Feldman, M. et al. 2002. Is NF-κappaB a useful therapeutic target in rheumatoid arthritis?. Annals of the Rheumatic Diseases 61, pp. 13-18., article number: supplement 2. (10.1136/ard.61.suppl_2.ii13)

2001

• Foxwell, B. M. J., Yoshimura, S., Bondeson, J., Brennan, F. M. and Feldmann, M. 2001. High efficiency gene transfer is an efficient way of defining therapeutic targets: a functional genomics approach. Annals of the Rheumatic Diseases 60, pp. 13-17. (10.1136/ard.60.90003.iii13)
• Bondeson, J., Yoshimura, S., Calder, V., Brennan, F. M., Foxwell, B. M. J. and Feldmann, M. 2001. Antigen presentation by dendritic cells is NF kappa B dependent in vitro and in vivo [abstract]. Arthritis & Rheumatism 44(9), pp. S213., article number: 962. (10.1002/1529-0131(200109)44:9+<::AID-ART426>3.0.CO;2-7/abstract)
• Bondeson, J. 2001. Everard Home, John Hunter, and cutaneous horns: a historical review. American Journal of Dermatopathology 23(4), pp. 362-369.
• Bondeson, J. 2001. Pachydermodactily as a cause of painful swelling of the knuckles: Successful treatment with intralesional steroids [letter]. Clinical and Experimental Rheumatology 19(4), pp. 481-482.
• Yoshimura, S., Bondeson, J., Brennan, F. M., Foxwell, B. M. and Feldman, M. 2001. Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. European Journal of Immunology 31(6), pp. 1883-1893. (10.1002/1521-4141(200106)31:6<1883::AID-IMMU1883>3.0.CO;2-V)
• Bondeson, J. and Maini, R. N. 2001. Tumour necrosis factor as a therapeutic target in rheumatoid arthritis and other chronic inflammatory diseases: the clinical experience with infliximab (REMICADE). International Journal of Clinical Practice 55(3), pp. 211-216.
• Bondeson, J. 2001. Dicephalus conjoined twins: A historical review with emphasis on viability. Journal of Pediatric Surgery 36(9), pp. 1435-1444. (10.1053/jpsu.2001.26393)
• Feldmann, M., Maini, R. N., Bondeson, J., Taylor, P., Foxwell, B. M. J. and Brennan, F. M. 2001. Cytokine blockade in rheumatoid arthritis. Advances in Experimental Medicine and Biology 490, pp. 119-127. (10.1007/978-1-4615-1243-1_13)
• Conron, M., Bondeson, J., Pantelidis, P., Beynon, H. L. C., Feldmann, M., duBois, R. M. and Foxwell, B. M. J. 2001. Alveolar macrophages and T Cells from sarcoid, but not normal lung, are permissive to adenovirus infection and allow analysis of NF- κ B-dependent signaling pathways. American Journal of Respiratory Cell and Molecular Biology 25(2), pp. 141-149. (10.1165/ajrcmb.25.2.4327)
• Yoshimura, S., Bondeson, J., Foxwell, B. M. J., Brennan, F. M. and Feldmann, M. 2001. Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. International Immunology 13(5), pp. 675-683. (10.1093/intimm/13.5.675)

2000

• Bondeson, J., Feldmann, M. and Maini, R. N. 2000. TNF as a therapeutic target. Immunologist 8(6), pp. 136-140.
• Bondeson, J. 2000. Two historical cases of giant epidermoid cyst of the skull, treated surgically. Journal of the Royal Society of Medicine 93(11), pp. 597-599.
• Bondeson, J., Brennan, F., Foxwell, B. and Feldmann, M. 2000. Effective adenoviral transfer of IkappaBalpha into human fibroblasts and chondrosarcoma cells reveals that the induction of matrix metalloproteinases and proinflammatory cytokines is nuclear factor-kappaB dependent. The Journal of Rheumatology 27(9), pp. 2078-2089.
• Foxwell, B. M. J., Bondeson, J., Brennan, F. and Feldmann, M. 2000. Adenoviral transgene delivery provides an approach to identifying important molecular processes in inflammation: evidence for heterogenecity in the requirement for NFkappa B in tumour necrosis factor production. Annals of the Rheumatic Diseases 59(90001), pp. i54-i59. (10.1136/ard.59.suppl_1.i54)

1999

• Bondeson, J., Brennan, F., Foxwell, B. and Feldmann, M. 1999. NF-kappa B dependent pathways of matrix metalloproteinase induction in rheumatoid arthritis. Arthritis and Rheumatism -Atlanta- 42(9), pp. S198-S198. (10.1002/art.1780422107)
• Bondeson, J., Foxwell, B., Brennan, F. and Feldmann, M. 1999. Defining therapeutic targets by using adenovirus: blocking NF-kB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proceedings of the National Academy of Sciences of the United States of America 96(10), pp. 5668-5673. (10.1073/pnas.96.10.5668)
• Feldmann, M., Bondeson, J., Brennan, F. M., Foxwell, B. M. J. and Maini, R. N. 1999. The rationale for the current boom in anti-TNFα treatment. Is there an effective means to define therapeutic targets for drugs that provide all the benefits of anti-TNFα and minimise hazards?. Annals of the Rheumatic Diseases 58(Supp I), pp. 127-131. (10.1136/ard.58.2008.i27)

1993

• Bondeson, J. and Miles, A. E. W. 1993. Julia Pastrana, the nondescript: an example of congenital, generalized hypertrichosis terminalis with gingival hyperplasia. American Journal of Medical Genetics 47(2), pp. 198-212. (10.1002/ajmg.1320470213)
• Bondeson, J. 1993. Caroline Crachami, the Sicilian fairy: a further note. American Journal of Medical Genetics 46(4), pp. 471. (10.1002/ajmg.1320460427)