Dr Tamás Szakmany

2024

• Tume, L. N., Lynes, A. A., Waugh, V., Johnston, B. W., Kazi, A., Truman, N. and Szakmany, T. 2024. Nurses' decision‐making around gastric residual volume measurement in UK adult intensive care: A four‐centre survey. Nursing in Critical Care 29(5), pp. 916-922. (10.1111/nicc.13056)
• Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy, article number: dkae246. (10.1093/jac/dkae246)
• Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
• Sidhu, J. K. et al. 2024. Delayed mucosal anti-viral responses despite robust peripheral inflammation in fatal COVID-19. The Journal of Infectious Diseases 230(1), pp. e17-e29. (10.1093/infdis/jiad590)
• Cheema, H. A. et al. 2024. Efficacy and safety of corticosteroids for the treatment of community-acquired pneumonia: A systematic review and meta-analysis of randomized controlled trials. Journal of Critical Care 80, article number: 154507. (10.1016/j.jcrc.2023.154507)
• Villar, J. et al. 2024. Predicting the length of mechanical ventilation in acute respiratory disease syndrome using machine learning: The PIONEER Study. Journal of Clinical Medicine 13(6), article number: 1811. (10.3390/jcm13061811)
• McGuigan, P. J. et al. 2024. The effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal compared with conventional lung protective ventilation on cardiac function. Critical Care Explorations 6(1), article number: e1028. (10.1097/CCE.0000000000001028)
• Szakmany, T. et al. 2024. The ‘analysis of gene expression and biomarkers for point-of-care decision support in Sepsis‘ study; temporal clinical parameter analysis and validation of early diagnostic biomarker signatures for severe inflammation andsepsis-SIRS discrimination. Frontiers in Immunology 14, article number: 1308530. (10.3389/fimmu.2023.1308530)
• Griffiths, H. et al. 2024. Prone positioning is associated with increased insulin requirements in mechanically ventilated patients with COVID-19. Scientific Reports 14(1), article number: 27668. (10.1038/s41598-024-78904-3)

2023

• Villar, J. et al. 2023. Predicting ICU mortality in acute respiratory distress syndrome patients using machine learning: The Predicting Outcome and STratifiCation of severity in ARDS (POSTCARDS) Study. Critical Care Medicine 51(12), pp. 1638-1649. (10.1097/CCM.0000000000006030)
• Michael, B. D. et al. 2023. Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses. Nature Communications 14, article number: 8487. (10.1038/s41467-023-42320-4)
• Kloss, P. et al. 2023. Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study. Annals of Intensive Care 13(1), article number: 112. (10.1186/s13613-023-01201-1)
• Nazer, L. et al. 2023. Patient diversity and author representation in clinical studies supporting the Surviving Sepsis Campaign guidelines for management of sepsis and septic shock 2021: a systematic review of citations. BMC Infectious Diseases 23(1), article number: 751. (10.1186/s12879-023-08745-4)
• Villar, J., Szakmany, T., Grasselli, G. and Camporota, L. 2023. Redefining ARDS: a paradigm shift. Critical Care 27(1), article number: 416. (10.1186/s13054-023-04699-w)
• Lau, T. et al. 2023. Perspectives of statistician, microbiologist, and clinician stakeholders on the use of microbiological outcomes in randomised trials of antimicrobial stewardship interventions. Antibiotics, article number: 885. (10.3390/antibiotics12050885)
• RECOVERY, C. G. and Szakmany, T. 2023. Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet 401(10387), pp. 1499-1507. (10.1016/S0140-6736(23)00510-X)
• Adisa, A. et al. 2023. Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries. British Journal of Surgery (10.1093/bjs/znad092)
• Florescu, S. et al. 2023. Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19. Journal of the American Medical Association 329(14), pp. 1183-1196. (10.1001/jama.2023.4480)
• Harte, E. et al. 2023. Procalcitonin values fail to track the presence of secondary bacterial infections in COVID-19 ICU Patients. Antibiotics 12(4), article number: 709. (10.3390/antibiotics12040709)
• Tabah, A. et al. 2023. Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study. Intensive Care Medicine 49(2), pp. 178–190. (10.1007/s00134-022-06944-2)
• Goldswain, H. et al. 2023. The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection. Genome Biology 24(1), article number: 47. (10.1186/s13059-023-02881-5)
• Szakmany, T. 2023. When more could mean less intervention: the tale of tracheostomy timing in critical illness. Critical Care Medicine 51(2), pp. 333-335. (10.1097/CCM.0000000000005753)
• Rose, L. et al. 2023. Airway pressure release ventilation: a survey of UK practice [Correspondence]. British Journal of Anaesthesia 130(1), pp. e25-e27. (10.1016/j.bja.2022.10.017)
• Villar, J. et al. 2023. Clinical relevance of timing of assessment of ICU mortality in patients with moderate-to-severe Acute Respiratory Distress Syndrome. Scientific Reports 13(1), article number: 1543. (10.1038/s41598-023-28824-5)
• Cheema, H. A. et al. 2023. Awake prone positioning for non-intubated COVID-19 patients with acute respiratory failure: A meta-analysis of randomised controlled trials. Journal of Clinical Medicine 12(3), article number: 926. (10.3390/jcm12030926)
• Alsallakh, M. et al. 2023. Patterns of healthcare resource utilisation of critical care survivors between 2006 and 2017 in wales: a population-based study. Journal of Clinical Medicine 12(3), article number: 872. (10.3390/jcm12030872)
• Writing Committee for the REMAP-CAP Investigators, . and Szakmany, T. 2023. Long-term (180-day) outcomes in critically Ill patients with COVID-19 in the REMAP-CAP randomized clinical trial. Journal of the American Medical Association (JAMA) 329(1), pp. 39-51. (10.1001/jama.2022.23257)

2022

• Amado-Rodríguez, L. et al. 2022. Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study. Journal of Intensive Care 10, article number: 55. (10.1186/s40560-022-00648-x)
• Vink, E. et al. 2022. Viral coinfections in hospitalized coronavirus disease 2019 patients recruited to the international severe acute respiratory and emerging infections consortium WHO clinical characterisation protocol UK study. Open Forum Infectious Diseases 9(11), article number: ofac531. (10.1093/ofid/ofac531)
• Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
• Rubulotta, F. et al. 2022. Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients. BMJ Open 12(11), article number: e057010. (10.1136/bmjopen-2021-057010)
• NIHR Global Health Unit on Gobal Surgery, ., COVIDSurg Collaborative, . and Szakmany, T. 2022. Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries. The Lancet 400(10363), pp. 1607-1617. (10.1016/S0140-6736(22)01846-3)
• Griffiths, R. et al. 2022. INTEGRATE: A methodology to facilitate critical care research using multiple, linked electronic health records at population scale.. International Journal of Population Data Science 7(1), article number: 1724. (10.23889/ijpds.v7i1.1724)
• Hollinghurst, J. et al. 2022. SARS-CoV-2 infection risk among 77,587 healthcare workers: a national observational longitudinal cohort study in Wales, United Kingdom, April to November 2020. Journal of the Royal Society of Medicine 115(12), pp. 467-478. (10.1177/01410768221107119)
• Llewelyn, M. J. et al. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77(4), pp. 1189-1196. (10.1093/jac/dkac017)
• Cheema, H. A. et al. 2022. Probiotics for the prevention of ventilator-associated pneumonia: an updated systematic review and meta-analysis of randomised controlled trials. Nutrients 14(8), article number: 1600. (10.3390/nu14081600)
• Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)

2021

• Sakr, Y. et al. 2021. Do ventilatory parameters influence outcome in patients with severe acute respiratory infection? Secondary analysis of an international, multicentre14-day inception cohort study. Journal of Critical Care 66, pp. 78-85. (10.1016/j.jcrc.2021.08.008)
• Silversides, J. A. et al. 2021. Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial. Intensive Care Medicine 48(2), pp. 190-200. (10.1007/s00134-021-06596-8)
• Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
• Pathare, N., Szakmany, T., Hall, J. E. and Heurich, M. 2021. Plasma IgM levels differentiate between survivors and non-survivors of culture-positive and culture-negative sepsis and SIRS: a pilot study. Journal of Clinical Medicine 10(22), article number: 5391. (10.3390/jcm10225391)
• Szakmany, T. 2021. Postoperative continous positive airways pressue to prevent pneumonia, a re-intubation and death after major abdominal surgery: An International randomised trail. Lancet Respiratory Medicine 9(11), pp. 1221-1230. (10.1016/S2213-2600(21)00089-8)
• Pugh, R. J. et al. 2021. Long-term trends in critical care admissions in Wales. Anaesthesia 76(10), pp. 1316-1325. (10.1111/anae.15466)
• Tomas, E. et al. 2021. Correction to collaborators in acknowledgments in: Decision-making on withholding or withdrawing life support in the ICU: A worldwide perspective. Chest Journal 160(4), pp. 1576-1577. (10.1016/j.chest.2021.08.054)
• Unwin, H. J. A. et al. 2021. The use of different sepsis risk stratification tools on the wards and in emergency departments uncovers different mortality risks: results of the three Welsh national multicenter point-prevalence studies. Critical Care Explorations 3(10), article number: e0558. (10.1097/CCE.0000000000000558)
• Carroll, C. L. et al. 2021. Comparing the digital footprint of pulmonary and critical care conferences on Twitter. ATS Scholar 2(3), pp. 432–441. (10.34197/ats-scholar.2021-0041OC)
• Szakmany, T. and Duric, N. 2021. Cytokine inhibitors in COVID-19: looking back to move forward. Minerva Anestesiologica 87(8), pp. 848-850. (10.23736/S0375-9393.21.15837-7)
• Kopczynska, M. et al. 2021. Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards. Scientific Reports 11(1), article number: 16222. (10.1038/s41598-021-95648-6)
• Szakmany, T. et al. 2021. Differences in inflammatory marker kinetics between the first and second wave of COVID-19 patients admitted to the ICU: a retrospective, single-center study. Journal of Clinical Medicine 10(15), article number: 3290. (10.3390/jcm10153290)
• Szakmany, T., Hollinghurst, J., Pugh, R., Akbari, A., Griffiths, R., Bailey, R. and Lyons, R. A. 2021. Frailty assessed by administrative tools and mortality in patients with pneumonia admitted to the hospital and ICU inWales. Scientific Reports 11, article number: 13407. (10.1038/s41598-021-92874-w)
• Szakmany, T., Duric, N., Champanerkar, S., Rimmer, A. and James, C. 2021. Cytokine blockade in coronavirus disease 2019: keeping an open mind. Critical Care Explorations 3(5), article number: e0424. (10.1097/CCE.0000000000000424)
• Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
• McNamee, J. J. et al. 2021. Effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal vs standard care ventilation on 90-day mortality in patients with acute hypoxemic respiratory failure. Journal of the American Medical Association 326(11), pp. 1013-1023. (10.1001/jama.2021.13374)

2020

• Sinha, P. et al. 2020. Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study. Lancet Respiratory Medicine 8(12), pp. 1209-1218. (10.1016/S2213-2600(20)30366-0)
• Szakmany, T. 2020. Noninvasive ventilatory support in COVID-19: operating in the evidence free zone. Minerva Anestesiologica 86(11), pp. 1126-1128. (10.23736/S0375-9393.20.15158-7)
• Kopczynska, M. et al. 2020. Prevalence and outcomes of acute hypoxaemic respiratory failure in Wales: The PANDORA-WALES Study. Journal of Clinical Medicine 9(11), article number: 3521. (10.3390/jcm9113521)
• Lyons, J. et al. 2020. Understanding and responding to COVID-19 in Wales: protocol for a privacy protecting data platform for enhanced epidemiology and evaluation of interventions. BMJ Open 10(10), article number: e043010. (10.1136/bmjopen-2020-043010)
• Al Hassan, H., Cocks, E., Jesani, L., Lewis, S. and Szakmany, T. 2020. Clinical risk prediction scores in coronavirus disease 2019: beware of low validity and clinical utility. Critical Care Explorations 2(10), article number: e0253. (10.1097/CCE.0000000000000253)
• Baumer, T., Phillips, E., Dhadda, A. and Szakmany, T. 2020. Epidemiology of the first wave of COVID-19 ICU admissions in South Wales—the interplay between ethnicity and deprivation. Frontiers in Medicine 7, article number: 569714. (10.3389/fmed.2020.569714)
• Williams, E., Szakmany, T., Spernaes, I., Muthuswamy, B. and Holborn, P. 2020. Discrete-event simulation modeling of critical care flow: new hospital, old challenges. Critical Care Explorations 2(9), article number: e0174. (10.1097/CCE.0000000000000174)
• Stephens, T. J. et al. 2020. Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data. BMJ Quality and Safety 29(8), pp. 623-635. (10.1136/bmjqs-2019-009537)
• Tong, D. L., Kempsell, K. E., Szakmany, T. and Ball, G. 2020. Development of a bioinformatics framework for identification and validation of genomic biomarkers and key immunopathology processes and controllers in infectious and non-infectious severe inflammatory response syndrome. Frontiers in Immunology 11, article number: 380. (10.3389/fimmu.2020.00380)
• Szakmany, T. 2020. Anesthesia and immunomodulation: from basic science to clinical trials. Minerva Anestesiologica 86(2), pp. 126-128. (10.23736/S0375-9393.19.14327-1)
• Williams, E., Spearnes, I., Muthuswamy, B., Holborn, P. and Szakmany, T. 2020. 114: Mathematical modeling of critical care flow: how can we best cope with increasing demand?. Critical Care Medicine 48(1), pp. 40. (10.1097/01.ccm.0000618816.50090.25)

2019

• Blot, S. et al. 2019. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: 'AbSeS', a multinational observational cohort study and ESICM trials croup project. Intensive Care Medicine 45(12), pp. 1703-1717. (10.1007/s00134-019-05819-3)
• Carroll, C. L. et al. 2019. Growth of the digital footprint of the society of critical care medicine annual congress: 2014-2020. Critical Care Explorations 2(11), article number: 252. (10.1097/CCE.0000000000000252)
• Kopczynska, M. et al. 2019. Real world patterns of antimicrobial use and microbiology investigations in patients with sepsis outside the Critical Care Unit: Secondary analysis of three nation-wide point prevalence studies. Journal of Clinical Medicine 8(9), article number: 1337. (10.3390/jcm8091337)
• Carroll, C. L. et al. 2019. Lessons learned from web- and social media- based educational initiatives by pulmonary, critical care and sleep societies. Chest 155(4), pp. 671-679. (10.1016/j.chest.2018.12.009)
• Szakmany, T. 2019. Intravenous immunoglobulin in sepsis: can we find the right dose?. Minerva Anestesiologica 85(2), pp. 115-117. (10.23736/S0375-9393.18.13349-9)
• Burke, J., Wood, S., Hermon, A. and Szakmany, T. 2019. Improving outcome of sepsis on the ward: introducing the 'Sepsis Six' bundle. Nursing in Critical Care 24(1), pp. 33-39. (10.1111/nicc.12358)
• Szakmany, T., Walters, A. M., Pugh, R., Battle, C., Berridge, D. M. and Lyons, R. A. 2019. Risk factors for 1-year mortality and hospital utilisation patterns in critical care survivors: a retrospective, observational, population-based data-linkage study. Critical Care Medicine 47(1), pp. 15-22. (10.1097/CCM.0000000000003424)

2018

• Kopczynska, M. et al. 2018. Red-flag sepsis and SOFA identifies different patient population at risk of sepsis-related deaths on the general ward. Medicine 97(49), article number: e13238. (10.1097/MD.0000000000013238)
• Sakr, Y. et al. 2018. Sepsis in intensive care unit patients: Worldwide data from the ICON audit. Open Forum Infectious Diseases 5(12), article number: ofy313. (10.1093/ofid/ofy313)
• Kopczynska, M. et al. 2018. Sepsis-related deaths in the at-risk population on the wards: attributable fraction of mortality in a large point-prevalence study. BMC Research Notes 11(1), article number: 720. (10.1186/s13104-018-3819-2)
• Cortegiani, A. et al. 2018. Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database. Critical Care 22(157) (10.1186/s13054-018-2079-9)
• Madotto, F. et al. 2018. Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study. Intensive Care Medicine 44(5), pp. 564-577. (10.1007/s00134-018-5152-6)
• Szakmany, T. et al. 2018. Defining sepsis on the wards: results of a multi-centre point-prevalence study comparing two sepsis definitions. Anaesthesia 73(2), pp. 195-204. (10.1111/anae.14062)
• Wong, A. et al. 2018. Insertion rates and complications of central lines in the UK population: A pilot study. Journal of the Intensive Care Society 19(1), pp. 19-25. (10.1177/1751143717722914)

2017

• Pugh, R., Subbe, C. P., Thorpe, C. and Szakmany, T. 2017. The Baby Boom and later life: is critical care fit for the future?. Anestezjologia Intensywna Terapia 49(5), pp. 441-444. (10.5603/AIT.a2017.0078)
• Szakmany, T. et al. 2017. In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study. EJSO - European Journal of Surgical Oncology 43(12), pp. 2324-2332. (10.1016/j.ejso.2017.08.002)
• Ahmad, T. et al. 2017. Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery. British Journal of Anaesthesia 119(2), pp. 258-266. (10.1093/bja/aex185)
• Pugh, R., Harrison, W., Battle, C., Hancock, C. and Szakmany, T. 2017. Ventilator-associated events..perhaps not the answer. Journal of the Intensive Care Society 18(3), pp. 263-264. (10.1177/1751143717694917)
• Olusanya, O., Day, J., Kirk-Bayley, J. and Szakmany, T. 2017. Free Open Access Med(ical edu)cation for critical care practitioners. Journal of the Intensive Care Society 18(1), pp. 2-7. (10.1177/1751143716660726)
• Holst, B., Szakmany, T., Raby, A., Hamlyn, V., Durno, K., Hall, J. E. and Labéta, M. O. 2017. Soluble toll-like receptor 2 is a biomarker for sepsis in critically ill patients with multi-organ failure within 12 h of ICU admission. Intensive Care Medicine Experimental 5(1) (10.1186/s40635-016-0116-z)
• Frankling, C., Patel, J., Sharif, B., Szakmany, T., Melody, T., Gao, F. and Yeung, J. 2017. Audit of healthcare providers' compliance with the 1-h Sepsis Six Bundle when treating patients with confirmed or suspected sepsis in two acute NHS hospitals [Abstract]. Anaesthesia 72(S2), pp. 21. (10.1111/anae.13789)

2016

• Szakmany, T. et al. 2016. Sepsis prevalence and outcome on the general wards and emergency departments in Wales: Results of a multi-centre, observational, point prevalence study. PLOS ONE 11(12), article number: e0167230. (10.1371/journal.pone.0167230)
• Wong, A. et al. 2016. Immediate complications of cvc insertions: Feasibility pilot of a UK national audit (icnap). Critical Care Medicine 44(12)(S1), pp. 369. (10.1097/01.ccm.0000509850.70194.57)
• DePriest, A., Harwayne-Gidansky, I., Gerlach, A., Lough, M., Ackerman, A., Szakmany, T. and Carroll, C. 2016. Improving multidisciplinary involvement at the critical care congress through social media. Critical Care Medicine 44 (12(Supp 1), pp. 308. (10.1097/01.ccm.0000509606.52936.4e)
• Szakmany, T., Walters, A., Pugh, R., Battle, C. and Lyons, R. 2016. Risk factors of 30-day and 1-year mortality in critical care survivors in Wales between 2006-2015. Critical Care Medicine 44(12), pp. 104. (10.1097/01.ccm.0000508787.17502.0c)
• Szakmany, T. et al. 2016. Use of session-specific hashtags to enhance the reach of the critical care congress in social media. Critical Care Medicine 44(12)(S1), pp. 99. (10.1097/01.ccm.0000508767.99664.b3)
• Szakmany, T. 2016. Reactive oxygen species metabolites in sepsis: markers and mediators. Minerva Anestesiologica 82(12), pp. 1253-1255.
• Nobile, L. et al. 2016. The impact of extracerebral organ failure on outcome of patients after cardiac arrest: an observational study from the ICON database. Critical Care 20, article number: 368. (10.1186/s13054-016-1528-6)
• Pugh, R., Harrison, W., Harris, S., Roberts, H., Scholey, G. and Szakmany, T. 2016. Is HELICS the right way? Lack of chest radiography limits ventilator-associated pneumonia surveillance in Wales. Frontiers in Microbiology 7, article number: 1271. (10.3389/fmicb.2016.01271)
• Sharif, B. et al. 2016. Developing a digital data collection platform to measure the prevalence of sepsis in Wales. Journal of the American Medical Informatics Assocation 23(6), pp. 1185-1189. (10.1093/jamia/ocv208)
• Morgan, M., Szakmany, T., Power, S., Olaniyi, P., Kathy, R., Hall, J. E. and Eberl, M. 2016. Sepsis patients with first and second-hit infections show different outcomes depending on the causative organism. Frontiers in Microbiology 7, article number: 207. (10.3389/fmicb.2016.00207)
• Kempsell, K. E., Ball, G. and Szakmany, T. 2016. Issues in biomarker identification, validation and development for disease diagnostics in Public Health. Expert Review of Molecular Diagnostics 16(4), pp. 383-386. (10.1586/14737159.2016.1133300)

2015

• Szakmany, T. 2015. Mechanical ventilation on ECMO: unfinished business. Minerva Anestesiologica 81(11), pp. 1153-1155.
• Szakmany, T., Ellis, G., Sharif, B., Lundin, R. M. and Hall, J. E. 2015. Preventing sepsis [Correspondence]. The Lancet Infectious Diseases 15(11), pp. 1260-1260. (10.1016/S1473-3099(15)00376-X)
• Szakmany, T. and Heurich-Sevcenco, M. 2015. Immunomodulation in sepsis - why blunting the response doesn't work?. Journal of Infection 71(2), pp. 147-149. (10.1016/j.jinf.2015.04.019)
• Hermon, A., Pain, T., Beckett, P., Jerrett, H., Llewellyn, N., Lawrence, P. and Szakmany, T. 2015. Improving compliance with central venous catheter care bundles using electronic records. Nursing in Critical Care 20(4), pp. 196-203. (10.1111/nicc.12186)
• Szakmany, T. and Woodhouse, T. 2015. Use of cisatracurium in critical care: a review of the literature. Minerva Anestesiologica 81(4), pp. 450-460.
• Szakmany, T., Russell, P., Wilkes, A. R. and Hall, J. E. 2015. Effect of early tracheostomy on resource utilization and clinical outcomes in critically ill patients: meta-analysis of randomized controlled trials. British Journal of Anaesthesia 114(3), pp. 396-405. (10.1093/bja/aeu440)
• Lovas, A. and Szakmany, T. 2015. Haemodynamic effects of lung recruitment manoeuvres. Biomed Research International 2015, article number: 478970.

2014

• Szakmany, T., Ellis, G., Lundin, R., Pignatelli, L., Hall, J. and Morgan, P. 2014. Size of sepsis in Wales: Feasibility pilot. Critical Care Medicine 42(12), article number: A1446. (10.1097/01.ccm.0000457854.38137.95)
• Szakmany, T., Burke, J., Smith, L. and Hermon, A. 2014. Delivery of sepsis 6 by critical care outreach on the general wards: impact on outcome. Critical Care Medicine 42(12), article number: A1588. (10.1097/01.ccm.0000458444.18941.77)
• Davey, M. S. et al. 2014. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. Journal of Immunology 193(7), pp. 3704-3716. (10.4049/jimmunol.1401018)
• Nobile, L. et al. 2014. The impact of organ failure on outcome of patients after cardiac arrest [Abstract]. Intensive Care Medicine 40(SUPP 1), pp. S216-S216.
• Vincent, J. et al. 2014. Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit. The Lancet Respiratory Medicine 2(5), pp. 380-386. (10.1016/S2213-2600(14)70061-X)

2013

• Szakmany, T. and Russell, P. 2013. Impact of early tracheostomy on the icu patient: meta-analysis [Abstract]. Critical Care Medicine 41(12), pp. A94-A95. (10.1097/01.ccm.0000439539.05170.4c)
• Szakmany, T., Harrison, W., Roberts, H., Scholey, G. and Pugh, R. 2013. Surveillance for ventilator-associated pneumonia (YAP) in Wales: is helics the best way? [Abstract]. Critical Care Medicine 41(12), pp. A13-A13. (10.1097/01.ccm.0000439230.51661.ed)
• Hermon, A., Lawrence, P. and Szakmany, T. 2013. Using information technology to improve process compliance to central line insertion and maintenance bundles: 7 year experience [Abstract]. Intensive Care Medicine 39(Supp 2), pp. S473-S473.
• Burke, J., Smith, L., Wood, S., Hermon, A. and Szakmany, T. 2013. Sepsis bags: simple method to increase process compliance with sepsis six on the ward [Abstract]. Intensive Care Medicine 39(Supp 2), pp. S220-S220.
• Macarthur, K. and Szakmany, T. 2013. Can we use the CPIS score to aid antibiotic prescription in suspected ventilator associated pulmonary infections? [Abstract]. Intensive Care Medicine 39(Supp 2), pp. S313-S314.
• Rigby, M. R., Leong, T., Rider, C. and Szakmany, T. 2013. Expanding analytics to assess glycemic control in critical care [Abstract]. Intensive Care Medicine 39(Supp 2), pp. S363-S363.
• Morgan, M., Roberts, R., Olaniyil, P., Eberl, M., Hall, J. E. and Szakmany, T. 2013. Gamma-delta t cell activation by hmb-pp in early sepsis is associated with higher risk of death on the icu [Abstract]. Intensive Care Medicine 39(Supp 2), pp. S451-S452.
• Toth, I., Mikor, A., Leiner, T., Molnar, Z., Bogar, L. and Szakmany, T. 2013. Effects of IgM-enriched immunoglobulin therapy in septic-shock-induced multiple organ failure: Pilot study. Journal of Anesthesia 27(4), pp. 618-622. (10.1007/s00540-012-1553-9)
• Russell, P. and Szakmany, T. 2013. Meta-Analysis of the impact of early tracheostomy in ICU patients [Abstract]. Infection 41(Supp 1), pp. S67-S68.
• Raby, A. et al. 2013. Targeting the TLR co-receptor CD14 with TLR2-derived peptides modulates immune responses to pathogens. Science Translational Medicine 5(185), article number: 185ra64. (10.1126/scitranslmed.3005544)
• Morgan, M., Szakmany, T., Davey, M. S., Hall, J. E. and Eberl, M. 2013. Human gamma delta T cells in severe bacterial sepsis [Abstract]. British Journal of Anaesthesia 110(5), pp. 876-877. (10.1093/bja/aes490)

2012

• Durno, K., Holst, B., Wilkes, A., Shah, S., Labeta, M. O., Hall, J. E. and Szakmany, T. 2012. STLR-2 levels can discriminate between infective and non-infective origins of multi-organ dysfunction on ICU admission: a pilot study. Critical Care Medicine 40(12), pp. U138-U139. (10.1097/01.ccm.0000424713.57752.27)
• Minik, O. and Szakmany, T. 2012. Routine chest x-ray after percutaneous tracheostomy: nicety or necessity?[Abstract]. Critical Care Medicine 40(12), pp. U226-U226. (10.1097/01.ccm.0000425039.22892.48)
• Szakmany, T., Hermon, A. and Lawrence, P. 2012. From process compliance to zero infections: how can the use information technology impact on quality. Critical Care Medicine 40(12), pp. U46-U46.
• Rajanna, H. and Szakmany, T. 2012. Octagenerians on the ICU: are we doing it right? [Abstract]. Intensive Care Medicine 38(1), pp. S85-S86., article number: 301. (10.1007/s00134-012-2683-0)
• Hermon, A., Pain, T., Jerrett, H., Beckett, P. and Szakmany, T. 2012. Nurse-led quality improvement programme to reduce healthcare related infections: 4 years experience [Abstract]. Intensive Care Medicine 38(1), pp. S154-S154., article number: 550. (10.1007/s00134-012-2683-0)
• Burke, J., Wood, S., Smith, L., Hermon, A. and Szakmany, T. 2012. Critical care outreach: changing the game [Abstract]. Intensive Care Medicine 38(Supp 1), pp. S231-S231., article number: 855. (10.1007/s00134-012-2683-0)
• Gosavi, R. and Szakmany, T. 2012. High oxygenation index: bad lungs or bad doctors? [Abstract]. Intensive Care Medicine 38(Supp 1), pp. S141-S141., article number: 498. (10.1007/s00134-012-2683-0)
• Szakmany, T., Hauser, B. and Radermacher, P. 2012. N-acetylcysteine for sepsis and systemic inflammatory response in adults. Cochrane Database of Systematic Reviews 9, article number: CD006616. (10.1002/14651858.CD006616.pub2)

2011

• Szakmany, T., Albur, M., Thomas, M., Eberl, M. and Hall, J. E. 2011. Infection caused by (e)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (hmb-pp) producing pathogens increases risk of death on the ICU [Abstract]. Intensive Care Medicine 37(Supp 2), pp. S15-S15., article number: 37. (10.1007/s00134-011-2322-1)
• Hadfield, A. P., Naughton, J. and Szakmany, T. 2011. Appropriate blood transfusion on the ICU: audit of current practice in a district general hospital. Intensive Care Medicine 37(Supp 2), pp. S34-S34., article number: 115. (10.1007/s00134-011-2322-1)
• Szakmany, T., Pain, T., Beckett, P., Jerrett, H. and Hermon, A. 2011. Eliminating catheter related bloodstream infection on the intensive care unit: not a myth! [Poster Abstract]. Intensive Care Medicine 37, pp. S16-S16.
• Szakmany, T., Pain, T., Beckett, P., Jerrett, H., Lawrence, P. and Hermon, A. 2011. Effect of bundle compliance on reducing ventilator associated pneumonia in a mixed medical-surgical ICU [Abstract]. Intensive Care Medicine 37, pp. S206-S206.

2010

• Hauser, B., Molnar, Z. and Szakmany, T. 2010. Effect of Intravenous N-acetylcysteine in Acute Respiratory Distress Syndrome: A Systematic Review and Meta-analysis [Abstract]. Intensive Care Medicine 36(S2), pp. S357. (10.1007/s00134-010-2001-7)
• Kalman, S. and Szakmany, T. 2010. Consultant Working Patterns Could Impact Significantly on ICU Length of Stay: Evaluation of Daily vs Weekly Cover [Abstract]. Intensive Care Medicine 36(S2), pp. S324. (10.1007/s00134-010-2000-8)
• Szakmany, T., Hauser, B. and Radermacher, P. 2010. N-Acetylcysteine for Sepsis and Systemic Inflammatory Response: Systematic Review and Meta-Analysis [Abstract]. Intensive Care Medicine 36(S2), pp. S316. (10.1007/s00134-010-2000-8)
• Joseph, A., Nagarajan, S., Middleton, R. and Szakmany, T. 2010. Incidence and outcome Of ALI/ARDS in the average district general hospital [Abstract]. Intensive Care Medicine 36(S2), pp. S230. (10.1007/s00134-010-2000-8)
• Szakmany, T., Jones, D. and Jiwanmall, E. 2010. Increased Blood Glucose Variance Is Associated With Hypoglycaemia During Tight Glycaemic Control [Abstract]. Intensive Care Medicine 36(S2), pp. S173. (10.1007/s00134-010-1999-x)
• Beckett, P., Jerrett, H., Pain, T., Hermon, A. and Szakmany, T. 2010. Effect of Care Bundle Implementation on Catheter Related Bloodstream Infection on the Intensive Care Unit [Abstract]. Intensive Care Medicine 36(S2), pp. S126. (10.1007/s00134-010-1999-x)

2009

• Goldspink, D. F. et al. 2009. A study of presbycardia, with gender differences favoring ageing women. International Journal of Cardiology 137(3), pp. 236-245. (10.1016/j.ijcard.2008.06.086)

2008

• Baumann, J., Ghosh, S., Szakmany, T., Jancso, G., Ferencz, A., Roth, E. and Bogar, L. 2008. Short-term effects of N-acetylcysteine and ischemic preconditioning in a canine model of hepatic ischemia-reperfusion injury. European Surgical Research 41(2), pp. 226-230. (10.1159/000135707)

2007

• Toth, I., Leiner, T., Mikor, A., Szakmany, T., Bogar, L. and Molnar, Z. 2007. Hemodynamic and respiratory changes during lung recruitment and descending optimal positive end-expiratory pressure titration in patients with acute respiratory distress syndrome [Letter]. Critical Care Medicine 35(3), pp. 787-793. (10.1097/01.ccm.0000277060.87425.6b)

2006

• Szakmany, T., Dodd, M., Dempsey, G. A., Lowe, D., Brown, J. S., Vaughan, E. D. and Rogers, S. N. 2006. The influence of allogenic blood transfusion in patients having free-flap primary surgery for oral and oropharyngeal squamous cell carcinoma. British Journal of Cancer 94(5), pp. 647-653. (10.1038/sj.bjc.6603013)

2005

• Marton, S., Szakmany, T., Papp, A., Cseke, L. and Horvath, P. O. 2005. Does transthoracic compared to transhiatal resection alter the early postoperative course of oesophagectomy?. Diseases of the Esophagus 18(3), pp. 155-159. (10.1111/j.1442-2050.2005.00479.x)
• Molnar, T., Szabo, Z., Szakmany, T., Udvaros, E., Schmidt, E., Zambo, K. and Cziraki, A. 2005. Pulse-pressure predicts transient myocardial perfusion abnormalities during dipyridamole stress test [Abstract]. Journal of Hypertension 23(S2), pp. S84.
• Szakmany, T., Toth, I., Kovacs, Z., Leiner, T., Mikor, A., Koszegi, T. and Molnar, Z. 2005. Effects of volumetric vs. pressure-guided fluid therapy on postoperative inflammatory response: a prospective, randomized clinical trial. Intensive Care Medicine 31(5), pp. 656-663. (10.1007/s00134-005-2606-4)

2004

• Szakmany, T. and Molnar, Z. 2004. Increased glomerular permeability and pulmonary dysfunction following major surgery: correlation of microalbuminuria and PaO2/FiO2 ratio. Acta Anaesthesiologica Scandinavica 48(6), pp. 704-710. (10.1111/j.1399-6576.2004.00388.x)
• Molnar, Z., Mikor, A., Leiner, T. and Szakmany, T. 2004. Fluid resuscitation with colloids of different molecular weight in septic shock. Intensive Care Medicine 30(7), pp. 1356-1360. (10.1186/cc2597)
• Szakmany, T., Heigl, P. and Molnar, Z. 2004. Correlation between extravascular lung water and oxygenation in ALI/ARDS patients in septic shock: Possible role in the development of atelectasis?. Anaesthesia and Intensive Care 32(2), pp. 196-201.

2003

• Szakmany, T. and Molnar, Z. 2003. Procalcitonin levels do not predict mortality following major abdominal surgery [Letter]. Canadian Journal of Anaesthesia 50(10), pp. 1082-1083. (10.1007/BF03018387)
• Szakmany, T., Ghosh, S., Baumann, J., Ferencz, A. and Jancso, C. 2003. Effects of NAC and preconditioning on haemodynamics and indocyanine green clearance [Abstract]. Intensive Care Medicine 29(S1), pp. S70. (10.1007/s00134-003-1972-z)
• Szakmany, T., Mikor, A., Leiner, T. and Molnar, Z. 2003. Fluid resuscitation with colloids of different molecular weight in sepsis [Abstract]. Intensive Care Medicine 29(S1), pp. S27. (10.1007/s00134-003-1971-0)
• Molnar, Z., Szakmany, T. and Heigl, M. 2003. Microalbuminuria in severe sepsis: timing is difficult, "normal" levels are uncertain [Letter]. Intensive Care Medicine 29(8), pp. 1395-1395. (10.1007/s00134-003-1818-8)
• Szakmany, T., Marton, S. and Molnar, Z. 2003. Lack of effect of prophylactic N-acetylcysteine on postoperative organ dysfunction following major abdominal tumour surgery: A randomized, placebo-controlled, double-blinded clinical trial. Anaesthesia and Intensive Care 31(3), pp. 267-271.
• Molnar, Z., Szakmany, T. and Koszegi, T. 2003. Prophylactic N-acetylcysteine decreases serum CRP but not PCT levels and microalbuminuria following major abdominal surgery. A prospective, randomised, double-blinded, placebo-controlled clinical trial. Intensive Care Medicine 29(5), pp. 749-755. (10.1007/s00134-003-1723-1)
• Molnar, Z., Szakmany, T. and Heigl, P. 2003. Microalbuminuria does not reflect increased systemic capillary permeability in septic shock. Intensive Care Medicine 29(3), pp. 391-395. (10.1007/s00134-003-1651-0)

2002

• Szakmany, T., Marton, S. and Molnar, Z. 2002. Lack of effect of prophylactic N-acetylcysteine on organ dysfunction following major surgery [Abstract]. Intensive Care Medicine 28(S1), pp. S82.

2001

• Szakmany, T. and Molnar, Z. 2001. Clinical rather than biochemical variability may predict mortality following oesophagectomies [Abstract]. British Journal of Anaesthesia 86(2), pp. 320P. (10.1093/bja/86.2.303)

2000

• Molnar, Z., Szakmany, T., Koszegi, T. and Tekeres, M. 2000. Microalbuminuria and serum procalcitonin levels following oesophagectomy [Letter]. European Journal of Anaesthesiology 17(7), pp. 464-465.