Mr Branduff McAllister
Myfyriwr ymchwil, Psychological Medicine & Clinical Neurosciences, Yr Ysgol Meddygaeth
Mae'r cynnwys hwn ar gael yn Saesneg yn unig.
Trosolwg
Ymchil
Traethawd ymchwil
Identification and characterisation of genetic variation that modifies age at onset in Huntignton's Disease
Cyhoeddiadau
2024
- Kim, K. et al. 2024. Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease. Proceedings of the National Academy of Sciences 121(16), article number: e2322924121. (10.1073/pnas.2322924121)
- Hong, E. P. et al. 2024. Modification of Huntington's disease by short tandem repeats. Brain Communications 6(2), article number: fcae016. (10.1093/braincomms/fcae016)
2023
- Stöberl, N. et al. 2023. Mutant huntingtin confers cell-autonomous phenotypes on Huntington’s disease iPSC-derived microglia. Scientific Reports 13, article number: 20477. (10.1038/s41598-023-46852-z)
2022
- Lobanov, S. et al. 2022. Huntington’s disease age at motor onset is modified by the tandem hexamer repeat in TCERG1. npj Genomic Medicine 7, article number: 53. (10.1038/s41525-022-00317-w)
- Lee, J. et al. 2022. Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics 109(5), pp. 885-899. (10.1016/j.ajhg.2022.03.004)
- McAllister, B. et al. 2022. Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience 25, pp. 446-457. (10.1038/s41593-022-01033-5)
2021
- McAllister, B. et al. 2021. Timing and impact of psychiatric, cognitive, and motor abnormalities in Huntington disease. Neurology 96(19), pp. e2395-e2406. (10.1212/WNL.0000000000011893)
- Hong, E. P. et al. 2021. Association analysis of chromosome X to identify genetic modifiers of Huntington's disease. Journal of Huntington's Disease 10(3), pp. 367-375. (10.3233/JHD-210485)
2020
- Ellis, N. et al. 2020. Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry 87(9), pp. 857-865. (10.1016/j.biopsych.2019.12.010)
- McAllister, B. et al. 2020. The onset and prevalence of motor and psychiatric symptoms in Huntington’s disease. [Online]. bioRxiv. (10.1101/2020.05.26.116798)
2019
- McAllister, W. B. 2019. Identification and characterisation of genetic variation that modifies age at onset in Huntington’s disease. PhD Thesis, Cardiff University.
- Lee, J. et al. 2019. CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell 178(4), pp. 887-099.e14. (10.1016/j.cell.2019.06.036)
2018
- Massey, T., McAllister, B. and Jones, L. 2018. Methods for assessing DNA repair and repeat expansion in Huntington's Disease. In: Precious, S. V., Rosser, A. E. and Dunnett, S. B. eds. Huntington’s Disease., Vol. 1780. Methods in Molecular Biology Humana Press, pp. 483-495., (10.1007/978-1-4939-7825-0_22)