Mae'r cynnwys hwn ar gael yn Saesneg yn unig.
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Ymchil
Traethawd ymchwil
Hitting a moving target: The role of peptide-HLA flexibility during autoimmunity, transplant rejection, cancer and pathogen detection.
Cyhoeddiadau
2024
- Dolton, G. et al. 2024. HLA A*24:02-restricted T-cell receptors cross recognise bacterial and preproinsulin peptides in type 1 diabetes. Journal of Clinical Investigation 134(18), article number: e164535. (10.1172/JCI164535)
- Ferrari, M. et al. 2024. Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies. Nature Communications 15(1), article number: 1583. (10.1038/s41467-024-45854-3)
2021
- Hopkins, J. 2021. Plasticity at the T cell receptor-peptide-major
histocompatibility complex class I interface. PhD Thesis, Cardiff University.
2020
- Hopkins, J. R. et al. 2020. Peptide cargo tunes a network of correlated motions in human leukocyte antigens. FEBS Journal 287(17), pp. 3777-3793. (10.1111/febs.15278)
- Whalley, T. et al. 2020. GPU-accelerated discovery of pathogen-derived molecular mimics of a T-cell insulin epitope. Frontiers in Immunology 11, article number: 296. (10.3389/fimmu.2020.00296)
2019
- Madura, F. et al. 2019. TCR-induced alteration of primary MHC peptide anchor residue. European Journal of Immunology 49(7), pp. 1052-1066. (10.1002/eji.201948085)