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Determining the mechanism of insertional mutagenesis caused by CRISPR?Cas9 genome editing
Cyhoeddiadau
2024
- Mackay, H. L. et al. 2024. USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication. Nature Communications 15, article number: 8102. (10.1038/s41467-024-52250-4)
2022
- Fletcher, C. E. et al. 2022. A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer. Molecular Cancer 21, article number: 82. (10.1186/s12943-022-01540-w)
2021
- Dobbs, F. 2021. Determining the mechanism of off-target mutagenesis caused by CRISPR-Cas9 genome editing. PhD Thesis, Cardiff University.