Cancer Immunotherapy: significant breakthrough or unrealised potential?

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Professor Awen Gallimore, Division of Infection and Immunity, School of Medicine, Cardiff University

Many scientists and clinicians have pondered and theorised over the role the immune system plays in cancer for over a hundred and fifty years. Whilst many intriguing observations and experimental findings were recorded during this time, it is in the last twenty or so years that our scientific understanding of the relationship between the immune system and cancer has undergone advances that are significant enough to bring about real improvements to treatments of some patients with previously terminal disease. These treatments, termed immunotherapies, will be discussed in terms of those that are current as well as those which might be coming next.    

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