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Current projects list

Explore a few examples of our externally funded research projects.

Investigator(s)Sponsors School Award Value (£) Project TitleStart DateFinish Date
Ward Prof S (MEDIC), Prof K Singh (PSYCH), Prof N Harrison (MEDIC), Atack Prof J (BIOSI)Wellcome Trust £ 5,429,928.00 Phase 1 clinical studies for MDI-478: An AMPA receptor positive allosteric modulator for the treatment of cognitive impairment associated with schizophrenia01/07/202130/06/2024
Dr R Clarkson (BIOSI), Prof R Adams (MEDIC), Dr R Errington (MEDIC)Welsh Government (HCRW) £  1,775,475.00 Wales Cancer Bank01/04/202031/03/2025
Prof A Rosser (MEDIC), Prof M Li (MEDIC), Dr M Lelos (BIOSI)Medical Research Council £  1,597,164.80 Cell therapy for Huntington's disease, addressing critical knowledge gaps01/07/202030/06/2025
Dr H Pearson (BIOSI)Cancer Research UK £  1,529,634.00 Investigating resistance to PI3K pathway inhibitors to combat castration-resistant prostate cancer01/12/201930/11/2025
Fox Prof K (BIOSI), Sengpiel Prof F (BIOSI)Medical Research Council £  1,474,122.00 Cortical feedback circuits for sensory integration and control of synaptic plasticity01/08/202131/07/2026
Atack Prof J (BIOSI), Prof I Jones (MEDIC), Ward Prof S (MEDIC)Medical Research Council £  1,265,160.65 Allosteric modulators of extrasynaptic GABAA receptors for the treatment of postpartum depression01/09/202131/08/2023
Weightman Prof A (BIOSI), Mr R Stanton (MEDIC), Dr O Jones (MATHS), Connor Prof T (BIOSI), Durance Prof I (BIOSI), Jurkowski Dr T (BIOSI), Kille Prof P (BIOSI)Welsh Government £  1,228,500.00 Welsh Wastewater Programme Phase 301/06/202131/05/2022
Borri P ProfCommission of the European Communities £  1,036,153.00 Multiphoton microscopy and ultrafast spectroscopy: Imaging meets quantum01/04/201931/03/2023
Siezehnrubl Dr FMedical Research Council£
795,872.00
Defining the roles of fibroblast growth factor receptors on glioblastoma stem and non-stem cell populations01/05/201930/09/2022
Prof R Brambilla (BIOSI), Prof M Li (MEDIC) Medical Research Council  £     774,154.00 Targeting ERK signalling to emeliorate intellectual disability and autism spectrum disorder associated with chromosomal rearrangements at 16p11.201/11/201931/10/2023
Ward Prof S (MEDIC)Wellcome Trust £     663,437.00 Oncology01/01/202130/06/2022
John Prof R (BIOSI)Biotechnology and Biological Sciences Research Council £     641,220.00 Imprinted genes as master regulators of placental hormones01/07/202130/06/2024
Murray J ProfWelsh European Funding Office £     593,155.00 New players in organ size determination and homeostasis01/01/201931/10/2022
Connor T Dr (BIOSI)Medical Research Council £     586,390.00 CLIMB-BIG-DATA: A cloud infrastructure for big-data microbial bioinformatics01/04/202031/03/2025
Rosser Prof A (MEDIC)University Hospital Ulm£
568,517.00
Characterisation of the natural history of HD and assessment of feasibility of HD clinical research within the network of HD clinical centres01/01/201631/12/2022
Dos Anjos Afonso F DrBiotechnology and Biological Sciences Research Council £     524,329.00 Uncovering the most primitive human blood stem cell population and it's role in regeneration01/06/201931/05/2022
Prof K Fox (BIOSI), Prof R Honey (PSYCH), Dr J O'Neill (PSYCH)Biotechnology and Biological Sciences Research Council £     483,640.17 Cortical pathways and synaptic mechanisms for texture discrimination learning01/01/202031/12/2022
White-Cooper H Prof (BIOSI)Biotechnology and Biological Sciences Research Council £     478,154.00 Testis-specific activation of gene expression01/02/202031/01/2023
Martinez Garay I DrBiotechnology and Biological Sciences Research Council £     470,871.00 Cell-cell interactions in the regulation of neural progenitor fate: The role of PCDH1901/01/201931/12/2022
Prof M Smalley (BIOSI)Leo Foundation £     460,589.00 Establishing the keratinocyte stem cell basis for skin field cancerisation associated squamous cell carcinoma01/06/202031/05/2023
Latinkic Dr B (BIOSI)British Heart Foundation £     459,629.00 A new approach to target aberrant systolic calcium release and associated cardiac arrhythmias.01/10/202130/09/2026
Dr T Phesse (BIOSI), Dr R Jones (MEDIC), Prof J Staffurth (MEDIC), Pearson Dr H (BIOSI)Prostate Cancer Research Centre £     458,278.10 Targeting Wnt signaling to treat metastatic prostate cancer01/09/202131/08/2024
Dr J Lello (BIOSI)Biotechnology and Biological Sciences Research Council £     421,932.00 Eco-evolutionary dynamics of infectious diseases in host population networks01/10/201930/09/2024
Li M Prof (MEDIC)Commission of the European Communities £     415,000.00 Novel strategies for cell-based neural reconstruction01/01/202031/12/2023
John Prof R (BIOSI), Prof A Isles (MEDIC)Biotechnology and Biological Sciences Research Council £     401,387.70 Prenatal adversity and the intergenerational transmission of suboptimal maternal caregiving01/04/202131/03/2024
Kille P Prof, Weightman AJ ProfNatural Environment Research Council £     386,333.00 Classic and temporal mixture synergism in terrestrial ecosystems: Prevalence, mechanisms and impacts01/09/201830/09/2022
Hogan C DrCancer Research UK £     372,339.00 Unravelling mechanisms of cell competition in pancreatic cancer initiation. Potential novel targets for early detection01/05/201930/04/2022
Thomas K Dr (Harwood A Prof, MEDIC, PSYCH)Takeda Pharmaceutical Company Ltd £     370,093.63 To establish a scalable set of assay platforms against which the phenotype consequences of manipulating the identified exclusive targets can be screened and effects the drug compounds assessed to develop therapeutics for schizophrenia01/10/201830/09/2022
Harwood AJ Prof (Thomas K Dr, MEDIC, PSYCH)Takeda Pharmaceutical Company Ltd £     370,093.62 To establish a scalable set of assay platforms against which the phenotype consequences of manipulating the identified exclusive targets can be screened and effects the drug compounds assessed to develop therapeutics for schizophrenia01/10/201830/09/2022
Sengpiel F Prof (BIOSI), Vann Seralynne (PYSCH), Aggleton John (PYSCH)Biotechnology and Biological Sciences Research Council £     364,707.20 Integrating and storing visuo-spatial cues in the retrosplenial cortex01/12/201931/12/2022
Atack Prof J (BIOSI), Prof S Ward (MEDIC)Wellcome Trust £     348,062.00 Developing small molecules as a neurosteroid replacement strategy for treating postpartum psychosis01/01/202131/12/2022
Peters Dr OM (BIOSI), Dr R Sims (MEDIC), Allen Prof N (BIOSI)Medical Research Council £     347,342.74 Functional characterisation of newly identified Alzheimer's Disease associated genes in human and invertebrate model systems01/11/202131/10/2024
Harwood AJ Prof (with MEDIC)The Waterloo Foundation £     325,000.00 Future Minds Programme01/10/201830/09/2024
Parry L Dr(With MEDIC)Cancer Research UK £     261,747.20 Exploiting oncotropic bacteria for early detection of colorectal cancer01/07/201930/06/2022
Allen N Prof, Rosser A Prof (With MEDIC)Commission of the European Communities £     242,326.00 Training on advanced stem cell technologies in neurology01/10/201831/12/2023
Rosser A Prof, Allen N Prof(With MEDIC)Commission of the European Communities £     242,326.00 Training on advanced stem cell technologies in neurology01/10/201831/12/2023
Prof P Borri (BIOSI), Dr V Grieneisen (BIOSI), Dr A Maree (BIOSI)Cellesce Ltd, KTP £     233,478.00 To implement an advanced data analysis pipeline to identify key morphometric signatures from 3D images of screened organoids in drug trials and to classify organoid response for the assessment of therapeutic efficacy01/07/202031/12/2022
Prof J Atack (BIOSI), Prof S Ward (MEDIC)Wellcome Trust £     227,421.50 Proof-of-Concept for a5-GABAAR PAMs in the treatment of psychosis01/01/202131/12/2022
Dr A Fry (MEDIC), Prof A Tee (MEDIC), Dr H Williams (MEDIC), Prof N Allen (BIOSI)Welsh Government (HCRW) £     201,406.10 Wales Gene Park Centre01/04/202031/03/2025