The School's research staff and students have full access to the University-wide Central Biotechnology Services (CBS).
The CBS provides all state-of-the-art technologies and training required to perform laboratory-based biomedical research at the School of Dentistry.
In addition, the School also has its own high quality research facilities and equipment to underpin its in-house research programmes. Some examples are shown below.
Fluorescent Time Lapse Microscope
A microscopy system allowing automated image capture of fluorescently labelled or non-labelled cells in 4D. Associated software allows 4D rendering of cells providing cell tracking data in both space and time. The purchase of this equipment has been supported by CITER.
Atomic Force Microscope
The primary modes of operation of the Atomic Force Microscope are contact mode, non-contact mode, and dynamic contact mode. It can be used to study a wide variety of systems such as analyzing the crystals of amino acids and organic monolayers, DNA and RNA analysis; protein-nucleic acid complexes; chromosomes; cellular membranes; proteins and peptides; molecular crystals; ligand-receptor binding, polymers and a wide range of biomaterials.Example of a captured image: C. albicans adhering to silicone rubber. 24.7 Kb
ABI Prism 7000 qPCR machine
This system is a complete real-time PCR system that detects and quantitates nucleic acid sequences. In real-time PCR, cycle-by-cycle detection of accumulated PCR product is made paossible by combining thermal cycling, fluorescence detection and application software in a single instrument.
Gel Doc 3000
The Gel Doc system provides a fast, easy-to-use, high-resolution gel imaging system that is utilised primarily for visualising resolved protein and nucleic acid bands following electrophoretic procedures . The system includes darkroom, camera, UV- and white-light illumination, together with a comprehensive analysis software package.
Typhoon 9400 Phosphorimager
The Typhoon 9410 is a versatile scanner capable of scanning mounted and unmounted storage phosphor screens, gels, blots, tissue sections, microplates, microarrays and protein DIGE gels. The purchase of this equipment has been supported by CITER.
Circular Dichroism Spectrometer, Model 215
Circular Dichroism is a method for analyzing protein and nucleic acid secondary structure in solution, which is importance to verify the correct folding of recombinantly expressed proteins. It can be used to follow the changes in folding as a function of time, temperature, cosolutes and is also sensitive for measuring protein-ligand and nucleic acid-ligand interactions.